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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/10/26 15:03:51」(JST)

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  • A Decision Tree Based Classifier to Analyze Human Ovarian Cancer cDNA Microarray Datasets.
  • Tsai MH1,2, Wang HC3, Lee GW4, Lin YC5, Chiu SH6.
  • Journal of medical systems.J Med Syst.2016 Jan;40(1):21. doi: 10.1007/s10916-015-0361-9. Epub 2015 Nov 3.
  • Ovarian cancer is the deadliest gynaecological disease because of the high mortality rate and there is no any symptom in cancer early stage. It was often the terminal cancer period when patients were diagnosed with ovarian cancer and thus delays a good opportunity of treatment. The current common me
  • PMID 26531754
  • Epigenomic Regulation of Smad1 Signaling During Cellular Senescence Induced by Ras Activation.
  • Kaneda A1,2,3, Nonaka A4, Fujita T4, Yamanaka R4, Fujimoto M4,5, Miyazono K6, Aburatani H4.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1344:341-53. doi: 10.1007/978-1-4939-2966-5_22.
  • Epigenomic modification plays important roles in regulating gene expression during development, differentiation, and cellular senescence. When oncogenes are activated, cells fall into stable growth arrest to block cellular proliferation, which is called oncogene-induced senescence. We recently ident
  • PMID 26520136
  • Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β.
  • Valcourt U1,2,3,4,5, Carthy J6, Okita Y6,7, Alcaraz L1,2,3,4,5, Kato M7, Thuault S8, Bartholin L1,2,3,4,5, Moustakas A9,10.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1344:147-81. doi: 10.1007/978-1-4939-2966-5_9.
  • In recent years, the importance of the cell biological process of epithelial-mesenchymal transition (EMT) has been established via an exponentially growing number of reports. EMT has been documented during embryonic development, tissue fibrosis, and cancer progression in vitro, in animal models in v
  • PMID 26520123


  • Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells
  • Taniguchi Hiroaki,Hasegawa Hiroo,Sasaki Daisuke,Ando Koji,Sawayama Yasushi,Imanishi Daisuke,Taguchi Jun,Imaizumi Yoshitaka,Hata Tomoko,Tsukasaki Kunihiro,Uno Naoki,Morinaga Yoshitomo,Yanagihara Katsunori,Miyazaki Yasushi
  • Cancer Science 105(12), 1601-1608, 2014-12-01
  • … The PIM family (PIM-1, -2, -3) is made up of oncogenes that encode a serine/threonine protein kinase family. …
  • NAID 120005526601
  • 卵巣癌幹細胞および癌幹細胞ニッチとして機能する骨盤腹膜を標的とした新たな治療戦略(シンポジウム2(腫瘍) 難治性卵巣癌の克服を目指して,第66回日本産科婦人科学会学術講演会講演要旨)
  • 本原 剛志
  • 日本産科婦人科學會雜誌 66(11), 2761-2770, 2014-11-01
  • … Here we show that RNA interference-mediated transient depletion of the tumor suppressor p53 followed by retrovirus-mediated transfer of c-Myc and K-Ras oncogenes in EpCAM-expressing ovarian stem-like cells resulted in the generation of ovarian CSCs. …
  • NAID 110009872635
  • SS18-SSX-regulated miR-17 promotes tumor growth of synovial sarcoma by inhibiting p21WAF1/CIP1
  • Minami Yusuke,Kohsaka Shinji,Tsuda Masumi,Yachi Kazuhiro,Hatori Nobuaki,Tanino Mishie,Kimura Taichi,Nishihara Hiroshi,Minami Akio,Iwasaki Norimasa,Tanaka Shinya
  • Cancer Science 105(9), 1152-1159, 2014-09
  • … MicroRNA (miRNA) can function as tumor suppressors or oncogenes, and also as potential specific cancer biomarkers; …
  • NAID 120005515315


Learn what oncogenes are and how they can be studied to detect cancer at early stages. ... An octogene is a gene in the human body that has the potential to cause cancer. When a tumor is present, these cells mutate and cause ...
Cancer results from alterations in critical regulatory genes that control cell proliferation, differentiation, and survival. Studies of tumor viruses revealed that specific genes (called oncogenes) are capable of inducing cell transformation ...






  • 原癌遺伝子に変異が導入されて原癌遺伝子の働きが異常になった場合、この状態の遺伝子を癌遺伝子という。
  • K-rasc-erbB2N-mycc-mycc-abl/bcrBcl-2


  [★] 癌遺伝子

WordNet   license wordnet

「a gene that disposes normal cells to change into cancerous tumor cells」
transforming gene