出典: meddic


Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/18 23:42:02」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase.
  • Zhang R1.
  • Journal of cellular physiology.J Cell Physiol.2015 Aug;230(8):1697-701. doi: 10.1002/jcp.24926.
  • Nicotinamide adenine dinucleotide (NAD) and its phosphorylated form, NADP, play essential roles in numerous cellular processes in all organisms. NADP maintains a pool of its reducing equivalent, NADPH, which regenerates cellular oxidative defense systems to counteract oxidative damages. Mitochondria
  • PMID 25641397
  • Upregulation of microRNA‑492 induced by epigenetic drug treatment inhibits the malignant phenotype of clear cell renal cell carcinoma in vitro.
  • Wu A1, Wu K1, Li M1, Bao L1, Shen X1, Li S1, Li J1, Yang Z1.
  • Molecular medicine reports.Mol Med Rep.2015 Jul;12(1):1413-20. doi: 10.3892/mmr.2015.3550. Epub 2015 Mar 26.
  • Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer of the renal parenchyma. MicroRNAs (miRNAs) are non‑coding RNAs of ~22 nucleotides in length, which function as post‑transcriptional regulators. Recently, the downregulation of miRNA (miR)‑492 was observed to be associa
  • PMID 25815441
  • Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil.
  • Derissen EJ1, Hillebrand MJ2, Rosing H2, Schellens JH3, Beijnen JH4.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Jun 10;110:58-66. doi: 10.1016/j.jpba.2015.02.051. Epub 2015 Mar 10.
  • 5-Fluorouracil (5-FU) and its oral prodrug capecitabine are among the most widely used chemotherapeutics. For cytotoxic activity, 5-FU requires cellular uptake and intracellular metabolic activation. Three intracellular formed metabolites are responsible for the antineoplastic effect of 5-FU: 5-fluo
  • PMID 25804433


  • イヌのグルコース輸送体4(GluT4)の分子構造と組織発現
  • 落合 秀治,吉村 彰紘,印牧 信行,佐藤 礼一郎,恩田 賢
  • 麻布大学雑誌 = Journal of Azabu University 26, 11-16, 2015-03-20
  • … Canine GluT4 was consisted of 1637 nucleotides encoding 510 amino acids, which is one amino acid longer than human and mouse. …
  • NAID 120005598383
  • cDNA cloning and characterization of a rhamnose-binding lectin SUL-I from the toxopneustid sea urchin Toxopneustes pileolus venom
  • Hatakeyama Tomomitsu,Ichise Ayaka,Yonekura Tomokazu,Unno Hideaki,Goda Shuichiro,Nakagawa Hideyuki
  • Toxicon 94, 8-15, 2015-02
  • … The SUL-I gene contains an open reading frame of 927 nucleotides corresponding to 308 amino acid residues, including 24 residues of a putative signal sequence. …
  • NAID 120005526604
  • Nutrients and non-volatile taste compounds in Chinese mitten crab by-products
  • Guo Yan-Ru,Gu Sai-Qi,Wang Xi-Chang [他]
  • Fisheries science 81(1), 193-203, 2015-01
  • NAID 40020352431


02 Aug Show at Woodruff’s kelly No comments If you’re looking for a fun time with loud rock, groovy breakdowns, and great music, Buttonsphere is the band for you. So get up! Leap Year is groovy tunes for groovy dudes. ...
noun Biochemistry. any of a group of molecules that, when linked together, form the building blocks of DNA or RNA: composed of a phosphate group, the bases adenine, cytosine, guanine, and thymine, and a pentose sugar, in RNA ...






  • 核酸塩基+糖+リン酸
  • ヌクレオシドの糖の部分に1個以上のリン酸基がエステル結合した物質


  • De novo pathway
アミノプテリンが途中の合成系路を阻害する ← モノクローナル抗体の作成における選抜に利用される (関:HAT培地)
  • Salvage pathway]
  • 2通りの経路がある
  • 1. thymidine→…→nucleptode
thymidine kinase(TK)が触媒
hupoxanthine guanine phosphoribosyl transferase(HGPRT)が関与


  [★] ヌクレオチド

WordNet   license wordnet

「a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA)」