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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/05/16 13:19:03」(JST)

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Alphabaculovirus is a genus of viruses, in the family Baculoviridae. Winged insects, arthropods, lepidoptora, hymenoptera, diptera, and decapoda serve as natural hosts. There are currently 32 species in this genus including the type species Autographa californica multiple nucleopolyhedrovirus.^[1]^[2]

Taxonomy

Group: dsDNA

Order: Unassigned

Family: Baculoviridae
- Genus: Alphabaculovirus
  Adoxophyes honmai nucleopolyhedrovirus
  
  Agrotis ipsilon multiple nucleopolyhedrovirus
  
  Agrotis segetum nucleopolyhedrovirus
  
  Antheraea pernyi nucleopolyhedrovirus
  
  Anticarsia gemmatalis multiple nucleopolyhedrovirus
  
  Autographa californica multiple nucleopolyhedrovirus
  
  Bombyx mori nucleopolyhedrovirus
  
  Buzura suppressaria nucleopolyhedrovirus
  
  Choristoneura fumiferana DEF multiple nucleopolyhedrovirus
  
  Choristoneura fumiferana multiple nucleopolyhedrovirus
  
  Choristoneura rosaceana nucleopolyhedrovirus
  
  Chrysodeixis chalcites nucleopolyhedrovirus
  
  Clanis bilineata nucleopolyhedrovirus
  
  Ectropis obliqua nucleopolyhedrovirus
  
  Epiphyas postvittana nucleopolyhedrovirus
  
  Euproctis pseudoconspersa nucleopolyhedrovirus
  
  Helicoverpa armigera nucleopolyhedrovirus
  
  Hyphantria cunea nucleopolyhedrovirus
  
  Leucania separata nucleopolyhedrovirus
  
  Lymantria dispar multiple nucleopolyhedrovirus
  
  Mamestra brassicae multiple nucleopolyhedrovirus
  
  Mamestra configurata nucleopolyhedrovirus A
  
  Mamestra configurata nucleopolyhedrovirus B
  
  Maruca vitrata nucleopolyhedrovirus
  
  Orgyia pseudotsugata multiple nucleopolyhedrovirus
  
  Spodoptera exigua multiple nucleopolyhedrovirus
  
  Spodoptera frugiperda multiple nucleopolyhedrovirus
  
  Spodoptera littoralis nucleopolyhedrovirus
  
  Spodoptera litura nucleopolyhedrovirus
  
  Thysanoplusia orichalcea nucleopolyhedrovirus
  
  Trichoplusia ni single nucleopolyhedrovirus
  
  Wiseana signata nucleopolyhedrovirus

^[2]

Structure

Viruses in Alphabaculovirus are enveloped. Genomes are circular, around 80-180kb in length. The genome codes for 100 to 180 proteins.^[1]

Genus	Structure	Symmetry	Capsid	Genomic arrangement	Genomic segmentation
Alphabaculovirus	Budded or Occluded		Enveloped	Circular	Monopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by nuclear pore export, and existing in occlusion bodies after cell death and remaining infectious until finding another host. Winged insects, arthropods, lepidoptora, hymenoptera, diptera, and decapoda serve as the natural host. Transmission routes are fecal-oral.^[1]

Genus	Host details	Tissue tropism	Entry details	Release details	Replication site	Assembly site	Transmission
Alphabaculovirus	Winged insects	Midgut then hemocoel; digestive gland epithelium (shrimps)	Glycoprotiens	Budding; Occlusion	Nucleus	Nucleus	Oral-fecal

References

^ ^a ^b ^c "Viral Zone". ExPASy. Retrieved 12 June 2015.
^ ^a ^b ICTV. "Virus Taxonomy: 2014 Release". Retrieved 12 June 2015.

External links

Viralzone: Alphabaculovirus
ICTV

English Journal

Cytopathology of the trachea of Bombyx mori (Lepidoptera: Bombycidae) to Bombyx mori nucleopolyhedrovirus.

Senem JV1, Torquato EF1, de Fátima Chasko Ribeiro L1, Brancalhão RM2.
Micron (Oxford, England : 1993).Micron.2016 Jan;80:39-44. doi: 10.1016/j.micron.2015.09.005. Epub 2015 Sep 11.
Bombyx mori is a holometabolous insect found only in germplasm banks and morphological data related of resistance and susceptibility to diseases is important when selecting hybrids for commercial and scientific interest. This study analyzed the cytopathology of B. mori trachea to BmNPV, isolated geo
PMID 26433931

A simple plasmid-based transient gene expression method using High Five cells.

Shen X1, Pitol AK1, Bachmann V1, Hacker DL2, Baldi L1, Wurm FM3.
Journal of biotechnology.J Biotechnol.2015 Dec 20;216:67-75. doi: 10.1016/j.jbiotec.2015.10.007. Epub 2015 Oct 23.
The High Five (H5) cell line, derived from the lepidopteran Trichoplusia ni, is one of the major insect cell hosts for the production of recombinant proteins using the baculovirus expression vector system (BEVS). Here, we describe a simple polyethylenimine (PEI)-based transient gene expression (TGE)
PMID 26476358

Eri silkworm (Samia ricini), a non-mulberry host system for AcMNPV mediated expression of recombinant proteins.

Hosamani M1, Basagoudanavar SH2, Sreenivasa BP2, Inumaru S3, Ballal CR4, Venkataramanan R2.
Journal of biotechnology.J Biotechnol.2015 Dec 20;216:76-81. doi: 10.1016/j.jbiotec.2015.10.006. Epub 2015 Oct 26.
The baculovirus expression system (BVES) based on Autographa californica nucleopolyhedrovirus (AcMNPV) is widely used for the expression of eukaryotic proteins. Several insect cells/larvae that are permissive to AcMNPV have been routinely used as hosts to express heterologous proteins. Domesticated
PMID 26467714

Japanese Journal

Functional analysis of antisense long non-coding RNAs transcribed from the Bombyx mori (Lepidoptera: Bombycidae) nucleopolyhedrovirus genome

Ishihara Genki,Kokusho Ryuhei,Shimada Toru [他]
Applied entomology and zoology 50(2), 155-167, 2015-05
NAID 40020470115

Construction of Adoxophyes honmai nucleopolyhedrovirus bacmid DNA by using a gene-repair BAC cassette

Saito Yasumasa,Kunimi Yasuhisa,Nakai Madoka
Applied entomology and zoology 50(1), 143-146, 2015-02
NAID 40020374502

Deletion analysis of a superoxide dismutase gene of Bombyx mori (Lepidoptera: Bombycidae) nucleopolyhedrovirus

Katsuma Susumu,Bando Hisanori,Shimada Toru
Applied entomology and zoology 50(1), 57-62, 2015-02
NAID 40020374331

Related Pictures

★リンクテーブル★

リンク元	「nuclear polyhedrosis virus」「核多核体病ウイルス」

「nuclear polyhedrosis virus」

Alphabaculovirus
Virus classification
Group:	Group I (dsDNA)
Family:	Baculoviridae
Genus:	Alphabaculovirus
Type Species
	Autographa californica multiple nucleopolyhedrovirus;