核酸結合

WordNet

executed with proper legal authority; "a binding contract"
the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
strip sewn over or along an edge for reinforcement or decoration
the capacity to attract and hold something
street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"

PrepTutorEJDIC

義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD
nucleusの複数形

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1. 分子遺伝学の原理 principles of molecular genetics
2. 母体血中の無細胞胎児核酸を使った出生前診断 prenatal diagnosis using cell free fetal nucleic acids in maternal blood
3. 急性骨髄性白血病の分子遺伝学 molecular genetics of acute myeloid leukemia
4. マンノース結合レクチン mannose binding lectin
5. リウマチ性疾患の治療における抗マラリア剤 antimalarial drugs in the treatment of rheumatic disease

English Journal

Melting behavior and ligand binding of DNA intramolecular secondary structures.

Maiti S, Kankia B, Khutsishvili I, Marky LA.AbstractWe use a variety of biophysical techniques to determine thermodynamic profiles, including hydration, for the unfolding of DNA stem-loop motifs (hairpin, a three-way junction and a pseudoknot) and their interaction with netropsin and random cationic copolymers. The unfolding thermodynamic data show that their helix-coil transition takes place according to their melting domains or sequences of their stems. All hairpins adopted the B-like conformation and their loop(s) contribute with an immobilization of structural water. The thermodynamic data of netropsin binding to the (5')-AAATT-(3')/TTTAA site of each hairpin show affinities of ~10(6-7)M(-1), 1:1 stoichiometries, exothermic enthalpies of -7 to -12kcal mol(-1) (-22kcal mol(-1) for the secondary site of the three-way junction), and water releases. Their interaction with random cationic copolymers yielded higher affinities of ~10(6)M(-1) with the more hydrophobic hairpins. This information should improve our current picture of how sequence and loops control the stability and melting behavior of nucleic acid molecules.
Biophysical chemistry.Biophys Chem.2011 Nov;159(1):162-71. Epub 2011 Jun 21.
We use a variety of biophysical techniques to determine thermodynamic profiles, including hydration, for the unfolding of DNA stem-loop motifs (hairpin, a three-way junction and a pseudoknot) and their interaction with netropsin and random cationic copolymers. The unfolding thermodynamic data show t
PMID 21752531

The role of polymer nanolayer architecture on the separation performance of anion-exchange membrane adsorbers: Part II. DNA and virus separations.

Bhut BV, Weaver J, Carter AR, Wickramasinghe SR, Husson SM.SourceDepartment of Chemical and Biomolecular Engineering and Center for Advanced Engineering Fibers and Films, Clemson University, 127 Earle Hall, Clemson, South Carolina 29634; telephone: +1-864-656-4502; fax: +1-864-656-0784.
Biotechnology and bioengineering.Biotechnol Bioeng.2011 Nov;108(11):2654-60. doi: 10.1002/bit.23222. Epub 2011 Jun 15.
The surface-initiated polymerization protocol developed in part I was used to prepare strong anion-exchange membranes with variable polymer chain graft densities and degrees of polymerization for DNA and virus particle separations. A focus of part II was to evaluate the role of polymer nanolayer arc
PMID 21618476

Japanese Journal

Oligomerization and DNA-Binding Capacity of Pmr, a Histone-Like Protein H1 (H-NS) Family Protein Encoded on IncP-7 Carbazole-Degradative Plasmid pCAR1

SUZUKI Chiho,YUN Choong-Soo,UMEDA Takashi,TERABAYASHI Tsuguno,WATANABE Kazuya,YAMANE Hisakazu,NOJIRI Hideaki
Bioscience, Biotechnology, and Biochemistry 75(4), 711-717, 2011
… Though Pmr formed high-order protein-DNA complexes and did not show preference for nucleic acid sequences, the C-terminal region of Pmr did, suggesting that the DNA-binding affinity of Pmr can be evaluated by using its C-terminal region. …
NAID 130000645292