norethandrolone

Norethandrolone
Systematic (IUPAC) name
	(17β)-17-ethyl-17-hydroxyester-4-en-3-one
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	52-78-8
ATC code	A14AA09
PubChem	CID 5858
ChemSpider	5649
UNII	P7W01638W6
KEGG	D07127
Synonyms	(8R,9S,10R,13S,14S,17S)-17-Ethyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Chemical data
Formula	C20H30O2
Mol. mass	302.451 g/mol
	SMILES O=C4\C=C3/[C@@H]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)CC)[C@@H]2CC3)C)CC4;
	InChI InChI=1S/C20H30O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h12,15-18,22H,3-11H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1 ; Key:ZDHCJEIGTNNEMY-XGXHKTLJSA-N ;
(what is this?) (verify)

ノルエタンドロロン

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/07/23 23:09:37」(JST)

wiki en

[Wiki en表示]

Norethandrolone is an anabolic steroid. This drug was approved for sale by the U.S. Food and Drug Administration (FDA) in 1965 under the trade name Nilevar^[1] and finds legitimate use as an androgen for cases of hormonal deficiency, treatment of patients with severe burns, after severe trauma and for certain forms of aplastic anemia. It is now only marketed in Australia, France and Switzerland, and as with all 17-alpha alkylated oral steroids, long-term use in high doses result in elevated liver enzymes and consequently cirrhosis.^[2]

References

^ W., Llewellyn. (2005). Anabolics. p. 156.
^ D., Lednicer. (2011). Steroid Chemistry at Glance. Wiley. p. 67.

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 胆汁うっ滞関連そう痒症 pruritus associated with cholestasis

English Journal

Rate-dependent effects of monoamine releasers on intracranial self-stimulation in rats: implications for abuse liability assessment.

Bauer CT1, Banks ML, Blough BE, Negus SS.
Behavioural pharmacology.Behav Pharmacol.2013 Sep;24(5-6):448-58. doi: 10.1097/FBP.0b013e328363d1a4.
'Rate dependency' in the discipline of behavioral pharmacology describes a phenomenon wherein the effect of a drug on the rate of a behavior varies systematically as a function of the baseline, predrug rate of that behavior. Historically, rate-dependency studies have compared drug effects on differe
PMID 23851484

The metabolism of anabolic-androgenic steroids in the greyhound.

McKinney AR1, Cawley AT, Young EB, Kerwick CM, Cunnington K, Stewart RT, Ambrus JI, Willis AC, McLeod MD.
Bioanalysis.Bioanalysis.2013 Apr;5(7):769-81. doi: 10.4155/bio.13.40.
BACKGROUND: Effective control of the use of anabolic-androgenic steroids (AASs) in animal sports is essential in order to ensure both animal welfare and integrity. In order to better police their use in Australian and New Zealand greyhound racing, thorough metabolic studies have been carried out on
PMID 23534422

In vitro study methodologies to investigate genetic aspects and effects of drugs used in attention-deficit hyperactivity disorder.

Grünblatt E1, Bartl J, Marinova Z, Walitza S.
Journal of neural transmission (Vienna, Austria : 1996).J Neural Transm (Vienna).2013 Jan;120(1):131-9. doi: 10.1007/s00702-012-0869-9. Epub 2012 Jul 26.
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children and adolescents, with up to 5 % affected worldwide. Twin and family studies on ADHD show its high familiality with heritability estimated around 70 %, but, to date, no specific polymorphism or
PMID 22833045

Japanese Journal

17α-Ethyl-5β-estrane-3α, 17β-diol, a biological marker for the abuse of norethandrolone and ethylestrenol in slaughter cattle

VAN PUYMBROECK M.,KUILMAN M. E. M.,MAAS R. F. M.,WITKAMP R. F.,LEYSSENS L.,VAN MIERT A. S. J. P. A. M.,HENDRIKS L.,VANDERZANDE D.,ADRIAENSENS P.,JACOBS M.-P.,RAUS J.
Journal of chromatography. B, Biomedical sciences and applications 728(2), 217-232, 1999-05-28
NAID 10024537314

Quantitative Evaluation of Fetal Virilization by Steroids. Anogenital Distance Method

川島邦夫,中浦槙介,長尾重之,田中悟,桑村司,大森義仁
先天異常 : 日本先天異常学会会報 : official journal of Congeital Anomalies Research Association of Japan 17(1), 47-51, 1977-03-30
NAID 110002726591

Quantitative Evaluation of Virilizing Activity of Steroids by Measuring Morphological Changes in Uro-genital Region of Rats

[他], , , , ,
Endocrinologia Japonica 22(5), 439-444, 1975
… Among these three parameters the abridgment in urovaginal septum was shown to be the most sensitive.<BR>A quantitative assay of virilizing activity of steroids in female fetuses was examined on rats treated subcutaneously with 17α-methyltestosterone and norethandrolone. … The relative potency of norethandrolone to 17α-methyltestosterone calculated on urovaginal septum length was 0.354 with fiducial limits of 0.293-0.446, and it was suggested that the virilizing activities of steroids can be evaluated quantitatively. …
NAID 130000956193

匿名

検索

案内

案内