非ステロイドの

WordNet

an organic compound that does no contain a steroid (同)nonsteroidal
an anti-inflammatory drug that does not contain steroids; "NSAIDs inhibit the activity of both Cox-1 and Cox-2 enzymes" (同)nonsteroidal anti-inflammatory drug, NSAID
not steroidal or not having the effects of steroid hormones

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/01/16 17:15:04」(JST)

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Nonsteroidal is a term used to describe a compound that is not a steroid and to indicate as such.

It is used in the name of nonsteroidal anti-inflammatory drugs (NSAIDs) to distinguish them from corticosteroids as a class of anti-inflammatory agents.^[1]

Nonsteroidal is also used to describe steroidergic drugs that are not steroid derivatives.^[2]^[3] Examples include the following:^[2]^[3]

Estrogens: benzestrol, bifluranol, DBE, diethylstilbestrol (stilbestrol), dienestrol, fosfestrol, hexestrol (dihydroxystilbestrol), methallenestril, methestrol, methestrol dipropionate, paroxypropione, prinaberel, and triphenylethylene, as well as many xenoestrogens
SERMs: acolbifene, afimoxifene, arzoxifene, bazedoxifene, broparestrol, chlorotrianisene, clomifene, clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, ethamoxytriphetol, fispemifene, idoxifene, lasofoxifene, levormeloxifene, miproxifene, nafoxidine, nitromifene, ormeloxifene, ospemifene, panomifene, pipendoxifene, raloxifene, sivifene, tamoxifen, tesmilifene, toremifene, trioxifene, zindoxifene, zuclomifene
Antiandrogens: apalutamide, bicalutamide, cimetidine, darolutamide, DIMP, enzalutamide, EPI-001, EPI-506, flutamide, hydroxyflutamide, inocoterone, ketoconazole, nilutamide, orteronel, RU-58642, RU-58841, and topilutamide
SARMs: AC-262,356, acetothiolutamide, andarine, BMS-564,929, enobosarm (ostarine), GW-501516, JNJ-28330835, LGD-2226, LGD-3303, LGD-4033, S-23, and S-40503
Miscellaneous: tanaproget (progestogen), finerenone (antimineralocorticoid), esaxerenone (antimineralocorticoid), apararenone (antimineralocorticoid), AZD5423 (glucocorticoid), AL082D06 (antiglucocorticoid), mapracorat (SGRM), and Org 214007-0 (SGRM)

References

^ Buer JK (Oct 2014). "Origins and impact of the term 'NSAID'". Inflammopharmacology. 22 (5): 263–7. doi:10.1007/s10787-014-0211-2. PMID 25064056.
^ ^a ^b Edward J. Pavlik (6 December 2012). Estrogens, Progestins, and Their Antagonists: Health Issues. Springer Science & Business Media. pp. 166–. ISBN 978-1-4612-4096-9.
^ ^a ^b Thomas Nogrady Professor of Medicinal Chemistry Concordia University (Emeritus); Donald F. Weaver Canada Research Chair and Professor of Medicine and Chemistry Dalhousie University (27 July 2005). Medicinal Chemistry : A Molecular and Biochemical Approach: A Molecular and Biochemical Approach. Oxford University Press, USA. pp. 322–. ISBN 978-0-19-802645-7.

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1. 心不全患者において使用をさけるべき、または慎重に使用するべき薬 drugs that should be avoided or used with caution in patients with heart failure
2. 成人におけるステロイド抵抗性およびステロイド依存性の潰瘍性大腸炎に対するアプローチ approach to adults with steroid refractory and steroid dependent ulcerative colitis
3. 即時型過敏反応に対する迅速な薬剤脱感作 rapid drug desensitization for immediate hypersensitivity reactions

English Journal

Amphiphilic naproxen prodrugs: differential scanning calorimetry study on their interaction with phospholipid bilayers.

Giuffrida MC1, Pignatello R2, Castelli F2, Sarpietro MG2.
The Journal of pharmacy and pharmacology.J Pharm Pharmacol.2017 Sep;69(9):1091-1098. doi: 10.1111/jphp.12754. Epub 2017 Jun 16.
PMID 28620994

Nonsteroid anti-inflammatory therapy suppresses the development of proliferative vitreoretinopathy more effectively than a steroid one.

Tikhonovich MV1, Erdiakov AK2, Gavrilova SA1.
International ophthalmology.Int Ophthalmol.2017 Jun 21. doi: 10.1007/s10792-017-0594-3. [Epub ahead of print]
PMID 28639085

Anti-inflammatory treatment and risk for depression after first-time stroke in a cohort of 147 487 Danish patients.

Wium-Andersen IK1, Wium-Andersen MK1, Jørgensen MB1, Osler M1.
Journal of psychiatry & neuroscience : JPN.J Psychiatry Neurosci.2017 Jun 20;42(5):160244. doi: 10.1503/jpn160244. [Epub ahead of print]
PMID 28632121