出典: meddic

  • n.

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「meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/01/30 12:22:41」(JST)

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  • A case of constitutional trisomy 3 mosaicism in a teenage patient with mild phenotype.
  • Kekis M1, Hashimoto S2, Deeg C1, Calloway I1, McKinney A1, Shuss C3, Hickey S3, Astbury C4.
  • European journal of medical genetics.Eur J Med Genet.2016 Nov;59(11):569-572. doi: 10.1016/j.ejmg.2016.10.002. Epub 2016 Oct 4.
  • Constitutional mosaicism for trisomy 3 is extremely rare, with only a few postnatally diagnosed cases reported in the literature. We report a case of constitutional trisomy 3 mosaicism in a 16-year-old female, who presented with chronic joint pain, easy bruising, joint hypermobility and dysmorphic f
  • PMID 27717910
  • A Surveillance System Ensures Crossover Formation in C. elegans.
  • Machovina TS1, Mainpal R1, Daryabeigi A2, McGovern O1, Paouneskou D2, Labella S3, Zetka M3, Jantsch V2, Yanowitz JL4.
  • Current biology : CB.Curr Biol.2016 Oct 1. pii: S0960-9822(16)31056-9. doi: 10.1016/j.cub.2016.09.007. [Epub ahead of print]
  • Crossover (CO) recombination creates a physical connection between homologs that promotes their proper segregation at meiosis I (MI). Failure to realize an obligate CO causes homologs to attach independently to the MI spindle and separate randomly, leading to nondisjunction. However, mechanisms that
  • PMID 27720619
  • EXTRA SPINDLE POLES (Separase) controls anisotropic cell expansion in Norway spruce (Picea abies) embryos independently of its role in anaphase progression.
  • Moschou PN1, Savenkov EI1, Minina EA1,2, Fukada K1, Reza SH1,2, Gutierrez-Beltran E1,2, Sanchez-Vera V1, Suarez MF3, Hussey PJ4, Smertenko AP5,6, Bozhkov PV1,2.
  • The New phytologist.New Phytol.2016 Oct;212(1):232-43. doi: 10.1111/nph.14012. Epub 2016 May 27.
  • The caspase-related protease separase (EXTRA SPINDLE POLES, ESP) plays a major role in chromatid disjunction and cell expansion in Arabidopsis thaliana. Whether the expansion phenotypes are linked to defects in cell division in Arabidopsis ESP mutants remains elusive. Here we present the identificat
  • PMID 27229374


  • Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age.
  • Dissection of rye B chromosomes, and nondisjunction properties of the dissected segments in a common wheat background
  • Cytological Studies of Aneuploidy in Eleocharis kamtschatica (Cyperaceae)
  • Cytologia : international journal of cytology 71(2), 141-147, 2006-06-25
  • NAID 10017390495


nondisjunction /non·dis·junc·tion/ (-dis-junk´shun) failure either of two homologous chromosomes to pass to separate cells during the first meiotic division, or of the two chromatids of a chromosome to pass to separate cells during ...
nondisjunction definition by American Heritage Dictionary noun The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis. Related Forms: nonˌdis·juncˈtion·al adjective The American ...



拡張検索meiotic nondisjunction










meiotic nondisjunction」


  • 減数分裂の不分離
  • ex.
  • トリソミーの原因となる