WordNet

create by mixing or combining
(chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight (同)chemical_compound
put or add together; "combine resources" (同)combine
an enclosure of residences and other building (especially in the Orient)
a whole formed by a union of two or more elements or parts
combine so as to form a whole; mix; "compound the ingredients" (同)combine
calculate principal and interest
composed of more than one part; "compound leaves are composed of several lobes; "compound flower heads"
consisting of two or more substances or ingredients or elements or parts; "soap is a compound substance"; "housetop is a compound word"; "a blackberry is a compound fruit"
combined into or constituting a chemical compound

PrepTutorEJDIC

(…になるように)〈要素・成分など〉'を'混ぜ合わせる《+『名』+『into』+『名』》;(…から)〈薬など〉'を'調合する,混ぜ合わせて作る《+『名』+『from』(『of』)+『名』》 / 《しばしば受動態で》〈めんどうな事・損害など〉'を'もっとひどくする / 〈利子〉'を'複利で計算する / (…と)話し合いをつける,妥協する《+『with』+『名』》 / 複合の,合成の / 『合成物』,混合物,調合物;化合物 / 複合語,合成語(classroom, heart-to-heartなどをいう)
(異民族の家屋・商館などがある)囲み地区,構内

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Faustino-Rocha AI1,2, Ferreira R3, Oliveira PA4,5, Gama A4,6, Ginja M4,5.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2015 Sep 19. [Epub ahead of print]
The administration of chemical carcinogens is one of the most commonly used methods to induce tumors in several organs in laboratory animals in order to study oncologic diseases of humans. The carcinogen agent N-methyl-N-nitrosourea (MNU) is the oldest member of the nitroso compounds that has the ab
PMID 26386719

Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation.

Brings S1, Zhang S2, Choong YS1, Hogl S1, Middleditch M2, Kamalov M3, Brimble MA3, Gong D1, Cooper GJ4.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Aug;1852(8):1610-8. doi: 10.1016/j.bbadis.2015.04.014. Epub 2015 Apr 18.
Advanced glycation end-products (AGEs) comprise a group of non-enzymatic post-translational modifications of proteins and are elevated in diabetic tissues. AGE-modification impairs the digestibility of collagen in vitro but little is known about its relation to collagen-degrading proteinases in vivo
PMID 25900786

Development of resistance to antiglioma agents in rat C6 cells caused collateral sensitivity to doxorubicin.

Stojković S1, Podolski-Renić A1, Dinić J1, Stanković T1, Banković J1, Hadžić S1, Paunović V2, Isaković A2, Tanić N1, Pešić M3.
Experimental cell research.Exp Cell Res.2015 Jul 15;335(2):248-57. doi: 10.1016/j.yexcr.2015.05.018. Epub 2015 May 27.
Chemoresistance is a severe limitation to glioblastoma (GBM) therapy and there is a strong need to understand the underlying mechanisms that determine its response to different chemotherapeutics. Therefore, we induced resistance in C6 rat glioma cell line, which considerably resembles the characteri
PMID 26026740

Lack of Carcinogenicity of Reserpine in Transgenic Mice Carrying a Human Prototype c-Ha-ras Gene (RasH2 Mice)

IMAOKA Masako,SATOH Hiroshi,FURUHAMA Kazuhisa
Journal of toxicologic pathology 17(2), 95-103, 2004-06-30
… The antihypertensive drug reserpine, a non-genotoxic rodent carcinogen (putative non-human carcinogen), was used as a test compound for validation of these transgenic mice. … A single intraperitoneal injection of N-methyl- N-nitrosourea (MNU) to rasH2 mice served as a positive control. …
NAID 10025851739

田中彰
藥學雜誌 120(6), 506-519, 2000-06-01
… In addition, the metabolism of n-propyl-N-nitrosourea, a carcinogen, in rats, and chemical modification of high molecular substances such as DNA, RNA and proteins by 1,1'-ethylene-bis(1-nitrosourea)(EBNU), a carcinostatic agent, were studied in vitro by the use of the tracer technique. …
NAID 110003648835

Utility of Transgenic Mice Carrying Human Prototype c-Ha-ras Gene for Alternative Carcinogenicity Testing of Chemicals : Negative Results with Methapyrilene Hydrochloride

OGASAWARA Hiroyuki,TSUTSUMI Masahiro,TAKEDA Kazunori,USUI Koji,KOBAYASHI Hiroyuki,MURAKAMI Hisako,TAKAGI Hidetoshi,KUMAGAI Toshio,KONISHI Yoichi
Journal of toxicologic pathology 12(4), 179-188, 1999-12-01
… N-methyl-N-nitrosourea (MNU) was used as a positive control compound to confirm that a positive response is elicited in the rasH2 model. …
NAID 130000064923