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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/08 19:07:23」(JST)

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  • Prognostic Factors in an Exercised Model of Chemically-induced Mammary Cancer.
  • Alvarado A1, Faustino-Rocha AI2, Ferreira R3, Mendes R4, Duarte JA5, Pires MJ6, Colaço B7, Oliveira PA8.
  • Anticancer research.Anticancer Res.2016 May;36(5):2181-8.
  • BACKGROUND/AIM: Estrogen receptor α (ERα) and Ki-67 are strong prognostic and predictive markers in woman breast cancer. This study aimed to evaluate the immunoexpression of prognostic factor markers ERα, Ki-67 proliferation index (Ki-67 PI) and the mitotic activity index (MAI) in mammary tumors
  • PMID 27127121
  • Synthesis and antitumor activity evaluation of a novel combi-nitrosourea prodrug: Designed to release a DNA cross-linking agent and an inhibitor of O(6)-alkylguanine-DNA alkyltransferase.
  • Sun G1, Zhang N1, Zhao L2, Fan T1, Zhang S1, Zhong R1.
  • Bioorganic & medicinal chemistry.Bioorg Med Chem.2016 May 1;24(9):2097-107. doi: 10.1016/j.bmc.2016.03.041. Epub 2016 Mar 25.
  • The drug resistance of CENUs induced by O(6)-alkylguanine-DNA alkyltransferase (AGT), which repairs the O(6)-alkylated guanine and subsequently inhibits the formation of dG-dC cross-links, hinders the application of CENU chemotherapies. Therefore, the discovery of CENU analogs with AGT inhibiting ac
  • PMID 27041398
  • Characterization of mammary adenocarcinomas in male rats after N-methyl-N-nitrosourea exposure-Potential for human male breast cancer model.
  • Yoshizawa K1, Yuki M2, Kinoshita Y3, Emoto Y2, Yuri T2, Shikata N4, Elmore SA5, Tsubura A2.
  • Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie.Exp Toxicol Pathol.2016 May;68(5):263-70. doi: 10.1016/j.etp.2016.01.005. Epub 2016 Feb 3.
  • The frequency of breast cancer in men is extremely rare, reported to be less than 1% and there is currently no available animal model for male mammary tumors. We compared the characteristics of various immunohistochemical markers in N-methyl-N-nitrosourea (MNU)-induced mammary adenocarcinomas in mal
  • PMID 26852374


  • KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR
  • Kamimura Daisuke,Katsunuma Kokichi,Arima Yasunobu,Atsumi Toru,Jiang Jing-jing,Bando Hidenori,Meng Jie,Sabharwal Lavannya,Stofkova Andrea,Nishikawa Naoki,Suzuki Hironao,Ogura Hideki,Ueda Naoko,Tsuruoka Mineko,Harada Masaya,Kobayashi Junya,Hasegawa Takanori,Yoshida Hisahiro,Koseki Haruhiko,Miura Ikuo,Wakana Shigeharu,Nishida Keigo,Kitamura Hidemitsu,Fukada Toshiyuki,Hirano Toshio,Murakami Masaaki
  • Nature communications 6, 7474, 2015-06
  • … Designing and using an N-ethyl-N-nitrosourea (ENU)-mutant mouse line, T-Red (naive T-cell reduced), we show that a point mutation in KDELR1 is responsible for the reduction in the number of naive T cells in this model owing to an increase in ISR. …
  • NAID 120005647268
  • Mead acid supplementation does not rescue rats from cataract and retinal degeneration induced by N-methyl-N-nitrosourea
  • Emoto Yuko,Yoshizawa Katsuhiko,Hamazaki Kei [他]
  • Journal of toxicologic pathology 28(1), 11-20, 2015
  • NAID 40020360976
  • Advances on genetic rat models of epilepsy
  • SERIKAWA Tadao,MASHIMO Tomoji,KURAMORO Takashi,VOIGT Birger,OHNO Yukihiro,SASA Masashi
  • Experimental Animals 64(1), 1-7, 2015
  • … N-ethyl-N-nitrosourea (ENU) mutagenesis provides a systematic approach which allowed us to develop two novel epileptic rat models: heat-induced seizure susceptible (Hiss) rats with an Scn1a missense mutation and autosomal dominant lateral temporal epilepsy (ADLTE) model rats with an Lgi1 missense mutation. …
  • NAID 130004921800


nitrosourea [ni-tro″so-u-re´ah] any of a group of cell cycle phase nonspecific, lipid soluble biological alkylating agents, including carmustine, lomustine, semustine, and streptozocin; they cross the blood-brain barrier and are used as ...
nitrosoureaとは。意味や和訳。[名詞] 〔薬学〕 ニトロソ尿素,ニトロソウレア:抗腫瘍しゅよう剤. - 80万項目以上収録、例文・コロケーションが豊富な無料英和和英辞典。 ... で始まる で一致する で終わる を説明文に含む を見出しに含む



拡張検索ethylnitrosourea」「nitrosourea compound」「methylnitrosourea




nitrosourea compound」