nitrogen mustard derivatives

ナイトロジェンマスタード誘導体

WordNet

1. resulting from or employing derivation; "a derivative process"; "a highly derivative prose style"
2. a compound obtained from, or regarded as derived from, another compound
3. (linguistics) a word that is derived from another word; "`electricity is a derivative of `electric"
4. any of several cruciferous plants of the genus Brassica
5. leaves eaten as cooked greens (同)mustard greens, leaf mustard, Indian_mustard
6. pungent powder or paste prepared from ground mustard seeds (同)table mustard
7. a common nonmetallic element that is normally a colorless odorless tasteless inert diatomic gas; constitutes 78 percent of the atmosphere by volume; a constituent of all living tissues (同)N, atomic number 7

PrepTutorEJDIC

1. 派生した,由来した;独創性のない,借り物めいた / 派生語 / 派生した物
2. カラシ(アブラナ属の植物の総称) / マスタード,粉(練り)からし
3. 『窒素』(気体元素;化学記号は『N』)

UpToDate Contents

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• 1. 非プラチナ製剤ベースの癌化学療法の神経学的合併症の概要 overview of neurologic complications of non platinum cancer chemotherapy
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• 5. 成人の古典的ホジキンリンパ腫生存者に対するアプローチの概要 overview of the approach to the adult survivor of classical hodgkin lymphoma

English Journal

• Determination of mustard gas hydrolysis products thiodiglycol and thiodiglycol sulfoxide by gas chromatography-tandem mass spectrometry after trifluoroacetylation.

• Popiel S1, Nawała J, Dziedzic D, Söderström M, Vanninen P.
• Analytical chemistry.Anal Chem.2014 Jun 17;86(12):5865-72. doi: 10.1021/ac500656g. Epub 2014 Jun 6.
• A method for detecting mustard gas degradation products thiodiglycol (TDG) and thiodiglycol sulfoxide (TDGO) in water and sediment samples using gas chromatography-tandem mass spectrometry (GC-MS/MS) after derivatization with 1-(trifluoroacetyl)imidazole (TFAI) was described. Selected reaction monit
• PMID 24831983

• Potentiation by caffeine of cytogenetic damage induced by steroidal derivatives in human lymphocytes in vitro.

• Mourelatos C1, Nikolaropoulos S2, Fousteris M2, Pairas G2, Argyraki M3, Lykidis D1, Fidani S3, Mourelatos D3, Lialiaris T4.
• Mutation research. Genetic toxicology and environmental mutagenesis.Mutat Res Genet Toxicol Environ Mutagen.2014 May 15;766:42-5. doi: 10.1016/j.mrgentox.2014.03.005. Epub 2014 Mar 25.
• We studied the effects of three newly synthesized steroidal derivatives of nitrogen mustards, alone or in combination with caffeine, on sister chromatid exchange (SCE) frequencies and on human lymphocyte proliferation kinetics. The agents have as alkylator functionalities either P-N,N-bis(2-chloroet
• PMID 24680952

• A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells.

• Jamieson SM1, Gu Y2, Manesh DM3, El-Hoss J3, Jing D3, Mackenzie KL3, Guise CP1, Foehrenbacher A2, Pullen SM2, Benito J4, Smaill JB1, Patterson AV1, Mulaw MA5, Konopleva M4, Bohlander SK6, Lock RB3, Wilson WR7.
• Biochemical pharmacology.Biochem Pharmacol.2014 Mar 1;88(1):36-45. doi: 10.1016/j.bcp.2013.12.019. Epub 2014 Jan 13.
• Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) metabolises steroid hormones, prostaglandins and xenobiotics, and activates the dinitrobenzamide mustard prodrug PR-104A by reducing it to hydroxylamine PR-104H. Here, we describe a functional assay for AKR1C3 in cells using the fluorogenic probe coumbe
• PMID 24434189

Japanese Journal

• ヒト脳腫瘍細胞におけるACNU耐性機構の研究

• Neurologia medico-chirurgica 27(9), 825-830, 1987-09-15
• NAID 110002277620

• Bis(haloalkyl)piperidine類の化学的反応性と抗腫瘍活性

• 藥學雜誌 100(11), 1151-1160, 1980-11-25
• NAID 110003650728

• Syntheses of New Cyclophosphamide Derivatives Having 1,3,4,2-Oxadiazaphosphorinane and Related heterocyclic Systems

• Chemical & pharmaceutical bulletin 25(7), 1582-1590, 1977-07-25
• NAID 110003622615

Related Links

• Nitrogen Mustard - Chemotherapy Drugs - Chemocare

Nitrogen Mustard, Mustine, and Mechlorethamine Hydrochloride are other names for Mechlorethamine. In some cases, health care professionals may use the trade name Mustargen or other names Nitrogen Mustard Drug type: ...

• From Warfare to Mainstay: Mustard Derivatives Play Evolving ...

... researchers and physicians bombarded nearly every tumor type with nitrogen mustard derivatives. Mustard compounds found a place in many of the chemotherapy cocktails that became the standard of care for most types of ...

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リンク元	「ナイトロジェンマスタード誘導体」
関連記事	「derivative」「mustard」「nitrogen」「nitrogen mustard」

「ナイトロジェンマスタード誘導体」

　　[★]

英

nitrogen mustard derivatives

「derivative」

　　[★]

• n.

• 誘導体、類縁体、系薬物、派生物

• adj.

• 派生的な

関

analog、analogue、derivate、relative

　 　 　 　

「mustard」

　　[★]

• n.

• (植物)カラシナ、マスタード

関

Brassica juncea、Indian mustard

　 　 　 　

「nitrogen」

　　[★]

• n.

• 窒素

関

N、N2、nitric

　 　

「nitrogen mustard」

　　[★] ナイトロジェンマスタード