ニトロフラゾン
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- nitrofural
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/09 15:23:32」(JST)
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Nitrofural
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| Systematic (IUPAC) name |
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5-nitro-2-furaldehyde semicarbazone
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| Clinical data |
| AHFS/Drugs.com |
Micromedex Detailed Consumer Information |
Pregnancy
category |
- US: C (Risk not ruled out)
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| Identifiers |
| CAS Registry Number |
59-87-0 Y |
| ATC code |
B05CA03 D08AF01 D09AA03 (dressing) P01CC02 S01AX04 S02AA02 QG01AX90 QP51AC02 |
| PubChem |
CID: 5447130 |
| DrugBank |
DB00336 Y |
| ChemSpider |
4566720 Y |
| UNII |
X8XI70B5Z6 Y |
| KEGG |
C08042 N |
| ChEMBL |
CHEMBL869 Y |
| Chemical data |
| Formula |
C6H6N4O4 |
| Molecular mass |
198.14 g/mol |
SMILES
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O=[N+]([O-])c1oc(/C=N/NC(=O)N)cc1
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InChI
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InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+ Y
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Key:IAIWVQXQOWNYOU-FPYGCLRLSA-N Y
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| N (what is this?) (verify) |
Nitrofural (INN, trade name Furacin) is a bactericidal compound used as an antibiotic most commonly in the form of ointments. Its use in medicine has become less frequent as safer and more effective products have become available[citation needed], and it has been discontinued in the US.[1] The substance is pale yellow and crystalline.
Other names include nitrofurazone and furacilin.
References
- ^ Drugs.com: Nitrofurazone (Topical route)
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Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
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Alveo-
late |
Apicom-
plexa |
Conoidasida/
(Coccidiostats) |
| Cryptosporidiosis |
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| Isosporiasis |
- trimethoprim/sulfamethoxazole#
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| Toxoplasmosis |
- pyrimethamine
- sulfadiazine
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|
|
| Aconoidasida |
| Malaria |
Individual
agents |
Hemozoin
inhibitors |
| aminoquinolines |
- (4-): amodiaquine#
- chloroquine#
- Tafenoquine
- (8-): primaquine#
- pamaquine
|
|
| 4-methanolquinolines |
- mefloquine#
- quinine#
- quinidine
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| Other |
|
|
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| Antifolates |
DHFR inhibitors
(antifols) |
- proguanil#
- chlorproguanil
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| Sulfonamides |
- sulfadoxine
- sulfamethoxypyrazine
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| Coformulation |
- sulfadoxine/pyrimethamine (SP)#
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Sesquiterpene
lactones |
- artemether#
- artesunate#
- dihydroartemisinin
- artemotil
- artemisinin
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| Other |
- atovaquone (with proguanil as Malarone)
- tetracycline
- doxycycline#
- clindamycin
- pyronaridine
- piperaquine
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|
|
Combi-
nations |
| Fixed-dose (coformulated) ACTs |
- artemether/lumefantrine#
- artesunate/amodiaquine (ASAQ)
- artesunate/mefloquine (ASMQ)
- dihydroartemisinin/piperaquine
- artesunate/pyronaridine
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Other combinations
(not co-formulated) |
- artesunate/SP
- artesunate/mefloquine
- quinine/tetracycline
- quinine/doxycycline
- quinine/clindamycin
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| Babesiosis |
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Cilio-
phora |
- Balantidiasis: Tetracycline
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Hetero-
kont |
- Blastocystosis: Metronidazole
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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Index of protozoan infection
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| Description |
- Alveolata
- Amoebozoa
- Excavata
- Protist
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| Disease |
- Amoebozoa
- Chromalveolate
- Excavata
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| Treatment |
- Drugs
- amoeboa
- chromalveolate
- excavata
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Drugs used for diseases of the ear (S02)
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| Infection |
- Acetic acid
- Aluminium acetotartrate
- Boric acid
- Chloramphenicol
- Chlorhexidine
- Ciprofloxacin
- Clioquinol
- Gentamicin
- Hydrogen peroxide
- Miconazole
- Neomycin
- Nitrofurazone
- Ofloxacin
- Polymyxin B
- Rifamycin
- Tetracycline
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| Corticosteroids |
- Betamethasone
- Dexamethasone
- Fluocinolone acetonide
- Hydrocortisone
- Prednisolone
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| Analgesics and anesthetics |
- Lidocaine
- Cocaine
- Phenazone
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Index of the ear
|
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Congenital
- Other
- Symptoms and signs
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| Treatment |
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UpToDate Contents
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Japanese Journal
- Chemical fate and changes in mutagenic activity of antibiotics nitrofurazone and furazolidone during aqueous chlorination
- Nakamura Hitomi,Kawakami Tsuyoshi,Niino Tatsuhiro,Takahashi Yasuo,Onodera Sukeo
- Journal of toxicological sciences 33(5), 621-629, 2008-12-01
- … Reactions of nitrofuran antibiotics (nitrofurazone (NFZ) and frazolidone (FZD)) with hypochlorite in aqueous solution were investigated under the conditions that simulate wastewater disinfection. …
- NAID 110007005561
- LC-MS/MSによる畜水産食品中のニトロフラゾンの定量
- 堀江 正一,田原 弥生,石井 里枝,橋本 和明,山岸 陽子
- 食品衛生学雑誌 49(3), 204-210, 2008-06-25
- 液体クロマトグラフィー/タンデム質量分析法(LC-MS/MS)による食肉，鶏卵，魚介類中に残留するニトロフラゾンの定量法を検討した．前処理は，0.2%メタリン酸-メタノール(6 : 4)混液で抽出し，Oasis HLB (200 mg)カートリッジを用いたクリーンアップにより試験溶液を調製した．LC-MS/MS条件は，マトリックスの影響の少ないネガティブモードを採用した．移動相にはギ酸(0.01% …
- NAID 10024453717
- Nitrofurazone-induced changes in the rat liver(Proceedings of the 32nd Annual Meeting)
- ITO Kyoko,KAJIKAWA Satoru,NII Aisuke,HANADA Takanori,DOI Kunio
- Journal of toxicological sciences 30(Supplement), S59, 2005-10-31
- NAID 110004041728
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