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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/25 15:55:29」(JST)

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  • Effects of Bayluscide on Bithynia siamensis goniomphalos, the first intermediate host of the human liver fluke, Opisthorchis viverrini, in laboratory and field trials.
  • Tesana S, Thapsripair P, Thammasiri C, Prasopdee S, Suwannatrai A, Harauy S, Piratae S, Khampoosa P, Kulsantiwong J, Donthaisong C, Chalokepanrat P, Viyanant V, Malone JB.SourceFood-Borne Parasite Research Group, Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen province 40002, Thailand.
  • Parasitology international.Parasitol Int.2011 Aug 16. [Epub ahead of print]
  • The molluscicidal effects of Bayluscide (niclosamide) were investigated on Bithynia siamensis goniomphalos, the first intermediate host of human liver fluke, Opisthorchis viverrini. Lethal concentrations of 50% (LC(50)) and 95% (LC(95)) against young and adult males were 0.38 and 0.80, 0.42 and 0.86
  • PMID 21864711
  • Niclosamide induces mitochondria fragmentation and promotes both apoptotic and autophagic cell death.
  • Park SJ, Shin JH, Kang H, Hwang JJ, Cho DH.SourceGraduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea.
  • BMB reports.BMB Rep.2011 Aug;44(8):517-22.
  • Mitochondrial dynamics not only involves mitochondrial morphology but also mitochondrial biogenesis, mitochondrial distribution, and cell death. To identify specific regulators to mitochondria dynamics, we screened a chemical library and identified niclosamide as a potent inducer of mitochondria fis
  • PMID 21871175


  • Intestinal cestodes
  • 伊藤 亮,Craig P
  • Current Opinion in Infectious Diseases 20(5), 524-532, 2007-Oct
  • … Most human intestinal cestode infections can be treated with a single oral dose of praziquantel or niclosamide. …
  • NAID 120003203337
  • Transport of Schistosoma japonicum cercariae and the feasibility of niclosamide for cercariae control
  • LOWE Debbie,XI Jinyu,MENG Xianhong,WU Zisong,QIU Dongchuan,SPEAR Robert
  • Parasitology international : official journal of the Japanese Society of Parasitology 54(1), 83-89, 2005-03-01
  • NAID 10015455278


Niclosamide (trade name Niclocide) is a teniacide ("tenia-" referring to tapeworm) in the anthelmintic family especially effective against cestodes that infect humans. It is also used as a piscicide.It is stressed that while antihelmintics are a drug ...


Description Niclosamide.pngNiclosamide; aventis brand of niclosamide Niclosamide 95%Tc; 98%Tc, 70%Wp; 75%Wp etcView Large Image of Niclosamideniclosamide niclosamide niclosamide Niclosamide tablet




anthelmintic, anthelmintics

antiplatyhelmintic agents Antitrematodals
binds tubulin benzimidazole (Triclabendazole#)
acetylcholinesterase inhibitor phosphonic acid (metrifonate)
Other/unknown quinoline (praziquantel#, oxamniquine#) · phenol (bithionol) · thiazole ([[niridazole]) · arylsulfonate (stibophen)
binds tubulin benzimidazole (albendazole#)
Other/unknown salicylanilide (niclosamide)# · aminoacridine (quinacrine) · butyrophenone (desaspidin) · chlorophenol (dichlorophen)
antinematodal agents
binds tubulin benzimidazole (mebendazole#, thiabendazole, albendazole#, fenbendazole, ciclobendazole, flubendazole)
chloride channel macrolide (ivermectin#)
NMDA tetrahydropyrimidine (pyrantel#, pyrantel pamoate, oxantel)
Other/unknown piperazine (piperazine · diethylcarbamazine#) · thiazole (levamisole#) · quinolinium (pyrvinium) · benzylammonium (bephenium) · naphthalenesulfonate (suramin#)  · tribendimidine