WordNet

the chief phagocytic leukocyte; stains with either basic or acid dyes (同)neutrophile
an immature leukocyte normally found in bone marrow

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/07/10 22:01:12」(JST)

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Basophilic^[1]

Eosinophilic^[2]

Neutrophilic^[3]

A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow, but not in circulating blood (except when caused by certain diseases).

Histology[edit]

When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells.

Numerous cytoplasmic granules are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules are peroxidase-positive, while basophilic granules are not.

The nuclear chromatin is coarser than that observed in myelocyte, but it is relatively faintly stained and lacks a well defined membrane.

The nucleus is fairly regular in contour (not indented), and seems to be 'buried' beneath the numerous cytoplasmic granules. (If the nucleus were indented, it would likely be a metamyelocyte.)

Maturation[edit]

Myelocytes are derived from promyelocytes and give rise to metamyelocytes.

Measurement[edit]

There is an internationally agreed method of counting blasts, with results from M1 upwards.

Additional images[edit]

Hematopoiesis

References[edit]

^ BU Histology Learning System: 01809loa
^ BU Histology Learning System: 01810loa
^ BU Histology Learning System: 01804loa

External links[edit]

Neutrophilic Myelocyte Presented by the University of Virginia
Eosinophilic Myelocyte Presented by the University of Virginia
Basophilic Myelocyte Presented by the University of Virginia
Image at queensu.ca

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1. 正常好中球の発生および動態 normal neutrophil development and kinetics
2. 白血球増多症および好中球増多症の定義およびメカニズム definition and mechanisms of leukocytosis and neutrophilia
3. 好中球二次顆粒欠損症 neutrophil specific granule deficiency
4. 先天性好中球減少症 congenital neutropenia
5. 骨髄造血の制御 regulation of myelopoiesis

English Journal

A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer.

Dumitru CA, Fechner MK, Hoffmann TK, Lang S, Brandau S.SourceDepartment of Otorhinolaryngology, University of Duisburg-Essen, Essen, Germany.
Journal of leukocyte biology.J Leukoc Biol.2012 Apr;91(4):591-8. Epub 2012 Jan 18.
Neutrophils are emerging as important mediators in cancer progression. Recent studies associated neutrophils with poor clinical outcome of HNC patients and showed that HNC induces recruitment, survival, and release of proinflammatory factors by neutrophils in vitro. The molecular mechanisms through
PMID 22262799

Japanese Journal

呼吸器・尿路感染症に対するSY5555の使用成績

CHEMOTHERAPY 42(Supplement1), 716-720, 1994
NAID 130004073159

Asialogangliosides as differentiation markers of rat erythropoietic and granulopoietic cells in rat bone marrow. Flow cytometric analysis of rat bone marrow cells using anti-asialoganglioside antibodies.