neutropenia

出典: meddic

好中球減少症

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「leukopenia in which the decrease is primarily in number of neutrophils (the chief phagocytic leukocyte)」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/05/13 16:40:51」(JST)

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英文文献

  • Impairment of thrombin generation in the early phases of the host response of sepsis.
  • Picoli-Quaino SK1, Alves BE2, Faiotto VB1, Montalvao SA1, De Souza CA3, Annichino-Bizzacchi JM3, De Paula EV4.Author information 1Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil.2Universidade Federal do Piaui, Teresina, PI, Brazil.3Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil.4Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. Electronic address: erich@unicamp.br.AbstractPURPOSE: The purpose was to investigate the presence of hypercoagulability in the very early phase of the host response to an infection in the clinical course of sepsis and septic shock.
  • Journal of critical care.J Crit Care.2014 Feb;29(1):31-6. doi: 10.1016/j.jcrc.2013.08.015. Epub 2013 Sep 24.
  • PURPOSE: The purpose was to investigate the presence of hypercoagulability in the very early phase of the host response to an infection in the clinical course of sepsis and septic shock.MATERIAL AND METHODS: Twenty-four patients with chemotherapy-associated febrile neutropenia were evaluated at base
  • PMID 24075296
  • Advances in the formulations of non-injection administration of docetaxel.
  • Zhang H, Dou J, Zhai Y, Liu A, Zhai G.Author information Department of Pharmaceutics, College of Pharmacy, Shandong University , Jinan , China and.AbstractAbstract Docetaxel is one of the most important anti-tumor drugs and has shown powerful therapeutic activity against breast cancer, non-small cell lung cancer, prostate cancer and so on. Owing to its poor water solubility and the efflux by P-glycoprotein (P-gp) and metabolism by CYP3A4 enzymes, it is generally administered as an injection form, the only manner for the current clinical application. However, the injection bearing polysorbate 80 and ethanol may cause adverse events such as severe hypersensitivity reactions, neutropenia, neurotoxicity, musculoskeletal toxicity and cumulative fluid retention, these adverse events limit clinical application and commercialization of docetaxel. Recently, various kinds of non-injection delivery systems for docetaxel have been developed to eliminate the polysorbate 80-based vehicle and increase the drug solubility. In this review, the non-injection delivery formulations of docetaxel for oral route, transdermal delivery, lung and rectal administration were discussed for future study and clinical application.
  • Journal of drug targeting.J Drug Target.2014 Feb;22(2):87-94. doi: 10.3109/1061186X.2013.839686. Epub 2013 Oct 7.
  • Abstract Docetaxel is one of the most important anti-tumor drugs and has shown powerful therapeutic activity against breast cancer, non-small cell lung cancer, prostate cancer and so on. Owing to its poor water solubility and the efflux by P-glycoprotein (P-gp) and metabolism by CYP3A4 enzymes, it i
  • PMID 24098909
  • Hyperthyroidism with concurrent FMS-like tyrosine kinase 3-internal tandem duplication-positive acute promyelocytic leukemia: A case report and review of the literature.
  • Jiang Y1, Hu K2, Xie W3, Zheng G3, Sun J3, Zheng Y3, Huang H3.Author information 1Department of Hematology, Bone Marrow Transplant Center, The First Affiliated Hospital of Zhejiang University Medical School, Hangzhou, Zhejiang 310003, P.R. China ; Program in Clinical Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310029, P.R. China.2Department of Hematology, The Second People's Hospital, Ningbo, Zhejiang 315000, P.R. China.3Department of Hematology, Bone Marrow Transplant Center, The First Affiliated Hospital of Zhejiang University Medical School, Hangzhou, Zhejiang 310003, P.R. China.AbstractNeutropenia is a common side-effect in hyperthyroid patients with long-term use of antithyroid drugs. This may be caused by drug-induced immune dysfunction or increased thyroxine hematologic toxicity, which usually returns to normal after medication is discontinued or the hyperthyroidism becomes well controlled. However, hyperthyroidism with pancytopenia is extremely rare. The current case report presents a hyperthyroid patient complicated with pancytopenia who had taken antithyroid drugs for 14 years. Bone marrow analysis revealed primary leuokocytes, indicating M3 acute leukemia. Genetic analysis revealed promyelocytic leukemia-retinoic acid receptor α fusion and FMS-like tyrosine kinase 3-internal tandem duplication. The genetic abnormality was also associated with thyroid hormonal functions. After a standard anti-M3 regimen was administed, the patient achieved complete remission and maintained stable thyroid functions. To the best of our knowledge, this is the first reported case of a patient with hyperthyroidism acquiring M3 leukemia harboring the FMS-like tyrosine kinase 3-internal tandem duplication.
  • Oncology letters.Oncol Lett.2014 Feb;7(2):419-422. Epub 2013 Nov 29.
  • Neutropenia is a common side-effect in hyperthyroid patients with long-term use of antithyroid drugs. This may be caused by drug-induced immune dysfunction or increased thyroxine hematologic toxicity, which usually returns to normal after medication is discontinued or the hyperthyroidism becomes wel
  • PMID 24396459

和文文献

  • 発熱性好中球減少症の予防と治療 (第5土曜特集 日本のがん診療UPDATE : 連携拠点病院と最新トピックス) -- (化学療法・腫瘍内科の現状)
  • 前立腺がんに対するカバジタキセルの適正使用について (特集 婦人科がん・泌尿器がん)
  • メロぺン特定使用成績調査(発熱性好中球減少症)の結果

関連リンク

Neutropenia or neutropaenia, from Latin prefix neutro-(neither, for neutral staining) and Greek suffix-πενία (deficiency), is a granulocyte disorder characterized by an abnormally low number of neutrophils. Neutrophils usually make up ...
Neutropenia. The risk of serious infection increases as the absolute neutrophil count (ANC) falls to the severely neutropenic range (< 500/µL). ... Concurrent anemia, thrombocytopenia, and/or an abnormal result on a ...

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Cyclic neutropenia.Neutropenia - GenericLook.comNeutropenia Congenita SeveraNeutropenia with Neutropenia by Hybrid Rasta Mama neutropenia showing normal amounts of red


★リンクテーブル★
リンク元好中球減少症」「好中球減少
拡張検索autoimmune neutropenia in an infant」「isoimmune neonatal neutropenia」「congenital neutropenia

好中球減少症」

  [★]

neutropenia
好中球減少顆粒球減少症 granulocytopenia
好中球



好中球減少」

  [★]

neutropenia
好中球減少症好中球


autoimmune neutropenia in an infant」

  [★] 乳児自己免疫性好中球減少症

isoimmune neonatal neutropenia」

  [★] 同種免疫新生児好中球減少症

congenital neutropenia」

  [★] 先天性好中球減少症




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