WordNet

a three-dimensional shape with six square or rectangular sides (同)cube
(computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
run on a block system; "block trains"
shape by using a block; "Block a hat"; "block a garment"
shape into a block or blocks; "block the graphs so one can see the results clearly"
stamp or emboss a title or design on a book with a block; "block the book cover"
the state of being joined together (同)conjunction, conjugation, colligation
an act of joining or adjoining things (同)adjunction
something that joins or connects (同)conjunction
the place where two or more things come together
a class of drugs that inhibit (block) some biological process (同)blocking_agent
a football player whose responsibility is to block players attempting to stop an offensive play
affecting or characteristic of both neural and muscular tissue

PrepTutorEJDIC

(木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする
〈U〉〈C〉連結すること(された状態),『結合』,連合,合体 / 〈C〉『結合点』,連結(接合,合流)点 / 〈C〉(鉄道の)『連絡駅』,接続駅

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 神経筋接合部に作用する毒素の概要 overview of neuromuscular junction toxins
2. 新生児における筋緊張低下を引き起こす末梢神経および筋肉の障害に関する概要 overview of peripheral nerve and muscle disorders causing hypotonia in the newborn
3. 重症疾患に関連する神経筋脱力 neuromuscular weakness related to critical illness
4. 新生児および幼児における神経筋接合部障害 neuromuscular junction disorders in newborns and infants
5. 神経筋接合部の電気診断学的評価 electrodiagnostic evaluation of the neuromuscular junction

English Journal

Combination of agrin and laminin increase acetylcholine receptor clustering and enhance functional neuromuscular junction formation In vitro.

Zhang BG1,2, Quigley AF3,4, Bourke JL3, Nowell CJ5, Myers DE1,2, Choong PF1,2, Kapsa RM4.
Developmental neurobiology.Dev Neurobiol.2016 May;76(5):551-65. doi: 10.1002/dneu.22331. Epub 2015 Aug 21.
Clustering of acetylcholine receptors (AChR) at the postsynaptic membrane is a crucial step in the development of neuromuscular junctions (NMJ). During development and after denervation, aneural AChR clusters form on the sarcolemma. Recent studies suggest that these receptors are critical for guidin
PMID 26251299

Successful treatment of Lambert-Eaton myasthenic syndrome in a small cell lung cancer patient using 3,4-diaminopyridine: A case report.

Hyun JW1, Kim SH1, Jeong IH1, Kim HT2, Kim HJ1.
Oncology letters.Oncol Lett.2016 Mar;11(3):1933-1935. Epub 2016 Jan 18.
Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of the neuromuscular junction that is characterized by muscle weakness. LEMS is usually associated with cancer, most commonly small cell lung cancer (SCLC). The potassium-channel blocker 3,4-diaminopyridine (3,4-DAP), has been previo
PMID 26998103

Metabotropic GABAB receptors mediate GABA inhibition of acetylcholine release in the rat neuromuscular junction.

Malomouzh AI1,2, Petrov KA1,2,3, Nurullin LF1,2,4, Nikolsky EE1,2,4.
Journal of neurochemistry.J Neurochem.2015 Dec;135(6):1149-60. doi: 10.1111/jnc.13373. Epub 2015 Oct 27.
Gamma-aminobutyric acid (GABA) is an amino acid which acts as a neurotransmitter in the central nervous system. Here, we studied the effects of GABA on non-quantal, spontaneous, and evoked quantal acetylcholine (ACh) release from motor nerve endings. We found that while the application of 10 μM of
PMID 26403151

Japanese Journal

Slow Ca<SUP>2+</SUP> (RAMIC) mobilization operated by postsynaptic neuronal nicotinic receptor regulates synaptic function at the mouse neuromuscular junction

出崎克也,恒枝宏史,木村郁子
日本薬理学雑誌 110(supplement), 114-119, 1997
… channel blocker tetrodotoxin prevented the generation of the slow Ca<SUP>2+</SUP> … These results suggest that RAMIC is mobilized through postsynaptic neuronal nAChR subtype to desensitize muscle nAChR at the neuromuscular junction. …
NAID 130000752850

Potentiation of Neuromuscular Blockade by Calcium Channel Blockers

TAKIGUCHI Mamoru,TAKAYA Tetsuo
Tokai journal of experimental and clinical medicine 19(3・4・5・6), 131-137, 1994-12
… A significant reduction was noticed in the amount of vecuronium needed to maintain steady neuromuscular blockade at 20% twitch height (T1) in patients given nicardipine intraoperatively. … Reversal of neuromuscular blockade with a choline esterase inhibitor (neo-stigmine) was not retarded by previous administration of Ca-channel blockers but concurrent administration of anticholine-esterase agent and Ca-channel blockers caused a delay in recovery from motor blockade. …
NAID 110004700729

動物起源の生物活性物質の解明

中嶋暉躬
藥學雜誌 113(2), 114-132, 1993-02-25
… Finally, over 15 kinds of neurotoxin were found from the spider venom which inhibit synaptic transmission of glutamate, both for lobster neuromuscular junction and mammaliam hippocampal neurons. …
NAID 110003649384