neurodegenerative disorder

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/14 19:44:46」(JST)

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英文文献

  • Rodent models of amyotrophic lateral sclerosis.
  • McGoldrick P, Joyce PI, Fisher EM, Greensmith L.SourceMRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, WC1N 3BG, UK; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, WC1N 3BG, UK. Electronic address: p.mcgoldrick@ucl.ac.uk.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2013 Sep;1832(9):1421-36. doi: 10.1016/j.bbadis.2013.03.012. Epub 2013 Mar 21.
  • Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterised by the degeneration of upper and lower motor neurons. Recent advances in our understanding of some of the genetic causes of ALS, such as mutations in SOD1, TARDBP, FUS and VCP have led to the generation of r
  • PMID 23524377
  • Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS.
  • Ravenscroft TA, Baker MC, Rutherford NJ, Neumann M, Mackenzie IR, Josephs KA, Boeve BF, Petersen R, Halliday GM, Kril J, van Swieten JC, Seeley WW, Dickson DW, Rademakers R.SourceDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Neurobiology of aging.Neurobiol Aging.2013 Sep;34(9):2235.e11-3. doi: 10.1016/j.neurobiolaging.2013.04.004. Epub 2013 Apr 28.
  • The nuclear protein fused in sarcoma (FUS) is found in cytoplasmic inclusions in a subset of patients with the neurodegenerative disorder frontotemporal lobar degeneration (FTLD-FUS). FUS contains a methylated arginine-glycine-glycine domain that is required for transport into the nucleus. Recent fi
  • PMID 23635657
  • ATXN2 CAG repeat expansions increase the risk for Chinese patients with amyotrophic lateral sclerosis.
  • Liu X, Lu M, Tang L, Zhang N, Chui D, Fan D.SourceDepartment of Neurology, Peking University Third Hospital, Beijing, China.
  • Neurobiology of aging.Neurobiol Aging.2013 Sep;34(9):2236.e5-8. doi: 10.1016/j.neurobiolaging.2013.04.009. Epub 2013 Apr 28.
  • Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with unclear etiology. Recently, intermediate CAG repeat expansions in ATXN2, the gene responsible for spinocerebellar ataxia type 2 (SCA2), have been identified as a possible genetic risk factor for ALS. In this study, we ana
  • PMID 23635656

和文文献

  • 臨床的にAlpers症候群と診断し、ミトコンドリア呼吸鎖異常症が確認された1剖検例
  • 松丸 重人/舟塚 真/中務 秀嗣/塩田 睦記/平野 嘉子/石垣 景子/宇都 健太/大澤 眞木子
  • 東京女子医科大学雑誌 83(E1), E301-E306, 2013-01-31
  • Alpers症候群は、予後不良の進行性神経変性疾患で、原因疾患のひとつにミトコンドリア異常症がある。臨床症状からAlpers症候群が疑われ、血液、髄液、MRS検査で乳酸値の上昇は認められなかったが、剖検での肝臓検体の検索により、ミトコンドリア呼吸鎖異常症が確認された1例を経験したので報告する。症例は1歳7ヵ月の女児で、乳児期発症の難治性持続性部分てんかん発作、退行、肝機能障害の臨床症状、脳波でのr …
  • NAID 110009559386
  • Writing errors in ALS related to loss of neuronal integrity in the anterior cingulate gyrus
  • Yabe Ichiro,Tsuji-Akimoto Sachiko,Shiga Tohru,Hamada Shinsuke,Hirata Kenji,Otsuki Mika,Kuge Yuji,Tamaki Nagara,Sasaki Hidenao
  • Journal of the neurological sciences 315(1-2), 55-59, 2012-04-15
  • … Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neuron and various cognitive deficits including writing errors. …
  • NAID 120003974403
  • Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer's Disease : Endoplasmic Reticulum Stress and Immunological Stress in Pathogenesis of Alzheimer's Disease
  • Hosoi Toru,Ozawa Koichiro
  • Journal of pharmacological sciences 118(3), 319-324, 2012-03-20
  • … Alzheimer's disease (AD) is an age-related neurodegenerative disorder, accompanied by neuronal loss and the formation of senile plaques in the brain. …
  • NAID 10030455370

関連リンク

Neurodegeneration is a key aspect of a large number of diseases that come under the umbrella of “neurodegenerative diseases.” Of these hundreds of different disorders, so far attention has been mainly focused on only a handful ...
neurodegenerative disorder Neurology A chronic progressive neuropathy characterized by selective and generally symmetrical loss of neurons in motor, sensory, or cognitive systems Types by area Cerebral cortex–Alzheimer's ...

関連画像

Neurodegenerative Disorders - Parkinson's  in eponymous neurodegenerative diseases for neurodegenerative disordersSRxA's Word on Health | Strategic News Neurodegenerative disorder age-related neurodegenerative diseases


★リンクテーブル★
リンク元neurologic degenerative disease」「degenerative neurologic disease」「degenerative neurologic disorder」「nervous system degenerative disease」「degenerative cerebellar disease
関連記事disorder」「disordered」「neurodegenerative

neurologic degenerative disease」

  [★]

central nervous system degenerative diseasedegenerative cerebellar diseasedegenerative neurologic diseasedegenerative neurologic disordernervous system degenerative diseaseneurodegenerative diseaseneurodegenerative disorder


degenerative neurologic disease」

  [★]

神経変性疾患

central nervous system degenerative diseasedegenerative cerebellar diseasedegenerative neurologic disordernervous system degenerative diseaseneurodegenerative diseaseneurodegenerative disorderneurologic degenerative disease


degenerative neurologic disorder」

  [★]

central nervous system degenerative diseasedegenerative cerebellar diseasedegenerative neurologic diseasenervous system degenerative diseaseneurodegenerative diseaseneurodegenerative disorderneurologic degenerative disease


nervous system degenerative disease」

  [★]

central nervous system degenerative diseasedegenerative cerebellar diseasedegenerative neurologic diseasedegenerative neurologic disorderneurodegenerative diseaseneurodegenerative disorderneurologic degenerative disease


degenerative cerebellar disease」

  [★]

神経変性疾患、変性脳疾患

degenerative neurologic diseasedegenerative neurologic disorderencephalopathynervous system degenerative diseaseneurodegenerative diseaseneurodegenerative disorderneurologic degenerative disease


disorder」

  [★]

  • 障害:個人的苦痛や機能の障害があるので「疾病」とは言えるものの、その背景にある臓器障害がもう一つはっきりしない場合に用いられる。(PSY.9)
  • n.
  • an untidy state; a lack of order or organization (⇔order)
  • violent behaviour of large groups of people
  • an illness that cause a part of the body to stop functioning correctly
  • 注意
disease <> illness <> disorder
  • vt.
  • 乱す、乱雑にする。(人)の(心身の)調子を狂わせる。
  • vi.

WordNet   license wordnet

「bring disorder to」
disarray

WordNet   license wordnet

「a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time"」
upset

WordNet   license wordnet

「a disturbance of the peace or of public order」

PrepTutorEJDIC   license prepejdic

「〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる」


disordered」

  [★]

WordNet   license wordnet

「not arranged in order」
unordered


neurodegenerative」

  [★]

  • adj.
  • 神経変性の
nerve degenerationneurodegeneration




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