WordNet

any organic substance that occurs in neural activity

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/09 06:18:24」(JST)

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Neurochemistry is the specific study of neurochemicals, including neurotransmitters and other molecules (such as psychopharmaceuticals) that influence the function of neurons. This field closely examines how these neurochemicals influence the network of neural operation. This evolving area of neuroscience offers a neurochemist a micro-macro connection between the analysis of organic compounds active in the nervous system and neural processes such as cortical plasticity, neurogenesis and neural differentiation.

History[edit source | edit]

The founding of neurochemistry as a discipline traces it origins to a series of "International Neurochemical Symposia", of which the first symposium volume published in 1954 was titled Biochemistry of the Developing Nervous System.^[1] These meetings led to the formation of the International Society for Neurochemistry and the American Society for Neurochemistry. These early gatherings discussed the tentative nature of possible neurotransmitter substances such as acetylcholine, histamine, substance P, and serotonin. By 1972, ideas were more concrete. Neurochemicals such as norepinephrine, dopamine, and serotonin were classified as "putative neurotransmitters in certain neuronal tracts in the brain."

References[edit source | edit]

^ Siegel, George J.; Albers, R.W., Brady, S.T., Price, D.L. (2006). Basic Neurochemistry, 7th Ed. Academic Press. ISBN 0-12-088397-X.

External links[edit source | edit]

Basic Neurochemistry online, searchable textbook.
American Society for Neurochemistry

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English Journal

Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years.

Kern S, Skoog I, Börjesson-Hanson A, Blennow K, Zetterberg H, Ostling S, Kern J, Gudmundsson P, Marlow T, Rosengren L, Waern M.SourceNeuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at The University of Gothenburg, Gothenburg, Sweden. Electronic address: silke.kern@vgregion.se.
Brain, behavior, and immunity.Brain Behav Immun.2013 Aug;32:153-8. doi: 10.1016/j.bbi.2013.03.011. Epub 2013 Apr 9.
OBJECTIVE: The literature regarding cerebrospinal fluid (CSF) cytokines in geriatric depression is sparse. The aim of this study was to examine associations between CSF interleukin-6 (IL-6) and related proinflammatory cytokines and current and future depression in a population-based sample of older
PMID 23583855

Farnesol: antinociceptive effect and histopathological analysis of the striatum and hippocampus of mice.

de Oliveira Júnior WM, Benedito RB, Pereira WB, de Arruda Torres P, Ramos CA, Costa JP, da Rocha Tomé A, de Sousa DP, de Freitas RM, de Fatima Formiga Melo Diniz M, de Almeida RN.SourceFederal University of Paraíba, Laboratory of Pharmaceutical Technology, CP 5009, CEP 58051-970, João Pessoa, Paraíba, Brazil Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutics Science, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil State University of Ceará, Av. Paranjana, 1700, Campus of Itaperi, CEP 60.740-000, Fortaleza, Ceará, Brazil Department of Physiology, Federal University of Sergipe, CEP 49100-000, Aracajú, Sergipe, Brazil.
Fundamental & clinical pharmacology.Fundam Clin Pharmacol.2013 Aug;27(4):419-426. doi: 10.1111/j.1472-8206.2012.01030.x. Epub 2012 Feb 20.
Farnesol, a sesquiterpene alcohol, has been shown to have antioxidant and anti-inflammatory properties. Recent studies have found that antioxidant compounds may exert a certain protective effect against neurotoxicity. The objective of this study was to evaluate the antinociceptive activity of farnes
PMID 22340189

Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder.

Trent S, Dean R, Veit B, Cassano T, Bedse G, Ojarikre OA, Humby T, Davies W.SourceBehavioural Genetics Group and Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK; Institute of Psychological Medicine and Clinical Neurosciences and MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK.
Psychoneuroendocrinology.Psychoneuroendocrinology.2013 Aug;38(8):1370-80. doi: 10.1016/j.psyneuen.2012.12.002. Epub 2012 Dec 29.
Chromosomal deletions at Xp22.3 appear to influence vulnerability to the neurodevelopmental disorders attention deficit hyperactivity disorder (ADHD) and autism. 39,X(Y*)O mice, which lack the murine orthologue of the Xp22.3 ADHD candidate gene STS (encoding steroid sulfatase), exhibit behavioural p
PMID 23276394

Japanese Journal

Integrative neurochemistry and neurobiology of social recognition and behavior analyzed with respect to CD38-dependent brain oxytocin secretion

Salmina Alla B.,Lopatina Olga,Kuvacheva Natalia V.,Higashida Haruhiro
Current Topics in Medicinal Chemistry 13(23), 2965-2977, 2013-12
This review summarizes the literature and our own data regarding the role of NAD+-glycohydrolase/CD38- controlled molecular mechanisms of hypothalamic and pituitary oxytocin secretion in social behavi …
NAID 120005368208

[学会見聞記] Neuro 2013 第36回日本神経科学大会 / 第56回日本神経化学会大会 / 第23回日本神経回路学会大会に参加して

世良真悠子
金沢大学十全医学会雑誌 122(2), 43-43, 2013-06
NAID 120005324086

Neuropharmacologic Studies on the Brain Serotonin1A Receptor Using the Selective Agonist Osemozotan

Matsuda Toshio
Biological and Pharmaceutical Bulletin 36(12), 1871-1882, 2013
… Alterations in serotonin (5-HT) neurochemistry have been implicated in the etiology of major neuropsychiatric disorders such as anxiety-spectrum disorders, depression, and schizophrenia. …
NAID 130003382066