WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
bring disorder to (同)disarray
a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time" (同)upset
a disturbance of the peace or of public order
easily agitated; "a nervous addict"; "a nervous thoroughbred"
of or relating to the nervous system; "nervous disease"; "neural disorder" (同)neural
not arranged in order (同)unordered

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる
『神経の』 / 『神経質な』,神経過敏な / 『心配な』,不安な

UpToDate Contents

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1. 成人における中枢神経系の原発性血管炎 primary angiitis of the central nervous system in adults
2. 神経系のライム病 nervous system lyme disease
3. 二次性中枢神経系リンパ腫の臨床症状および診断 clinical presentation and diagnosis of secondary central nervous system lymphoma
4. 中枢神経系病変を有するHIV感染患者に対するアプローチ approach to hiv infected patients with central nervous system lesions
5. ノカルジア症の臨床症状および診断 clinical manifestations and diagnosis of nocardiosis

English Journal

Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.

Vinatier G1, Corsi JM1, Mignotte B1, Gaumer S2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Sep 4;464(4):1060-5. doi: 10.1016/j.bbrc.2015.07.071. Epub 2015 Jul 22.
Polyglutamine diseases are nine dominantly inherited neurodegenerative pathologies caused by the expansion of a polyglutamine domain in a protein responsible for the disease. This expansion leads to protein aggregation, inclusion formation and toxicity. Despite numerous studies focusing on the subje
PMID 26210447

Neuroimaging studies and whole exome sequencing of PLA2G6-associated neurodegeneration in a family with intrafamilial phenotypic heterogeneity.

Kim YJ1, Lyoo CH2, Hong S3, Kim NY3, Lee MS4.
Parkinsonism & related disorders.Parkinsonism Relat Disord.2015 Apr;21(4):402-6. doi: 10.1016/j.parkreldis.2015.01.010. Epub 2015 Jan 17.
BACKGROUND: PLA2G6-associated neurodegeneration (PLAN) encompasses infantile- or atypical neuroaxonal dystrophy, and adult-onset dystonia-parkinsonism. Examination of the intrafamilial phenotypic variability of PLAN by neuroimaging data and background genetic differences has not been reported.METHOD
PMID 25634434

Functional and dysfunctional conformers of human neuroserpin characterized by optical spectroscopies and Molecular Dynamics.

Noto R1, Santangelo MG1, Levantino M2, Cupane A2, Mangione MR1, Parisi D3, Ricagno S4, Bolognesi M4, Manno M5, Martorana V1.
Biochimica et biophysica acta.Biochim Biophys Acta.2015 Feb;1854(2):110-7. doi: 10.1016/j.bbapap.2014.10.002. Epub 2014 Nov 6.
Neuroserpin (NS) is a serine protease inhibitor (SERPIN) involved in different neurological pathologies, including the Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB), related to the aberrant polymerization of NS mutants. Here we present an in vitro and in silico characterization o
PMID 25450507