WordNet
- reckoned in a direction opposite to that regarded as positive; "negative interest rates"
- a piece of photographic film showing an image with light and shade or colors reversed
- a reply of denial; "he answered in the negative"
- not indicating the presence of microorganisms or disease or a specific condition; "the HIV test was negative" (同)disconfirming
- having a negative charge; "electrons are negative" (同)electronegative, negatively charged
- characterized by or displaying negation or denial or opposition or resistance; having no positive features; "a negative outlook on life"; "a colorless negative personality"; "a negative evaluation"; "a negative reaction to an advertising campaign"
- expressing or consisting of a negation or refusal or denial
- having the quality of something harmful or unpleasant; "ran a negative campaign"; "delinquents retarded by their negative outlook on life"
- less than zero; "a negative number"
- act so as to bring into existence; "effect a change"
- a symptom caused by an illness or a drug; "the effects of sleep loss"; "the effect of the anesthetic"
- (of a law) having legal validity; "the law is still in effect" (同)force
- the central meaning or theme of a speech or literary work (同)essence, burden, core, gist
- an impression (especially one that is artificial or contrived); "he just did it for effect"
- produce; "The scientists set up a shock wave" (同)effectuate, set_up
- property of a personal character that is portable but not used in business; "she left some of her personal effects in the house"; "I watched over their effects until they returned" (同)personal_effects
PrepTutorEJDIC
- 『否定の』,反対の / 『消極的な』,控えめの / 陰電気の;(数値が)負の,マイナスの(minus);(写真が)陰画の,ネガの;(医学検査結果が)陰性の / 『否定』,拒否,「いやだ」と言うこと / 否定語[句] / 《the~》(特に討論会の)反対者側,反対派 / (電気分解に用いる)陰極板 / (数値の)負数 / (写真の)陰画,ネガ / 《しばしば受動態に用いて》…‘に'反対投票をする / =negate
- 〈C〉〈U〉『結果』 / 〈C〉〈U〉(…への)『効果』,効きめ,影響《+『on』(『upon』)+『名』》 / 〈C〉(色・音・形などの)印象,感銘 / 《複数形で》品物;身の回り品;動産,財産 / (結果として)…‘を'『もたらす』;〈目的など〉‘を'果たす,遂行する
UpToDate Contents
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English Journal
- A Comparative Summary on Antioxidant-like Actions of Timolol with Other Antioxidants in Diabetic Cardiomyopathy.
- Turan B1.
- Current drug delivery.Curr Drug Deliv.2015 Nov 22. [Epub ahead of print]
- Cellular signaling associated with cardiac β-adrenergic receptors (β-AR) is composed of coupled mechanism among β1-/β2-AR and Gs proteins with contribution of constitutive β3-AR coupling to Gi proteins. However, downregulation of β-ARs in the heart under pathological conditions are mediated wi
- PMID 26593438
- The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
- Reinke Y1, Gross S1, Eckerle LG2, Hertrich I2, Busch M2, Busch R1, Riad A1, Rauch BH3, Stasch JP4, Dörr M1, Felix SB5.
- European journal of pharmacology.Eur J Pharmacol.2015 Nov 15;767:1-9. doi: 10.1016/j.ejphar.2015.09.022. Epub 2015 Sep 25.
- In cardiovascular diseases, reduced responsiveness of soluble guanylate cyclase (sGC) to nitric oxide (NO) upon long-term application has led to the development of NO-independent sGC stimulators (heme-dependent) and sGC activators (heme-independent). Any direct inotropic or lusitropic effects of the
- PMID 26407652
- Effects of Ticagrelor on Ionic Currents and Contractility in Rat Ventricular Myocytes.
- Kucuk M1, Celen MC2, Yamasan BE2, Olgar Y2, Ozdemir S3.
- Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy.Cardiovasc Drugs Ther.2015 Oct;29(5):419-24. doi: 10.1007/s10557-015-6617-2.
- PURPOSE: Antiplatelet therapy has been widely used for management of patients with ischaemic heart diseases or thrombotic events. Experimental studies have shown that ticlopidine and clopidogrel decreased L-type Ca(2+) currents (ICaL), altered action potential (AP) duration and thence exerted negati
- PMID 26410045
Japanese Journal
- Influence of Acidosis on Cardiotonic Effects of Colforsin and Epinephrine: A Dose-Response Study
- Hagiya Keiichi,Takahashi Hiroshi,Isaka Yumi,Inomata Shinichi,Tanaka Makoto
- Journal of cardiothoracic and vascular anesthesia 27(5), 925-932, 2013-10
- … ObjectiveAcidosis produces a negative inotropic effect on cardiac muscle against which catecholamines and phosphodiesterase III inhibitors have limited therapeutic effects. …
- NAID 120005345618
- Effects of Landiolol Hydrochloride on Intractable Tachyarrhythmia After Pediatric Cardiac Surgery
- Tokunaga Chiho,Hiramatsu Yuji,Kanemoto Shinya,Takahashi-Igari Miho,Abe Masakazu,Horigome Hitoshi,Sakakibara Yuzuru
- The annals of thoracic surgery 95(5), 1685-1688, 2013-05
- … BackgroundWhile β-blockers can be effective in controlling tachyarrhythmias after pediatric cardiac surgery, a negative inotropic influence sometimes complicates their use. … The drug has higher β1:β2 selectivity ratio and a less negative inotropic effect. … The desired negative chronotropic effect was achieved without significant hemodynamic compromise. …
- NAID 120005296346
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- Negative inotropic effect was observed with the use of mBzR ligands, i.e. 4’-Cl-DZP, in various models including papillary muscle from right and ... ... Negative Inotropic And Physiological Effect Biology Essay Negative inotropic effect ...
★リンクテーブル★
[★]
- (変化などを)もたらす。(目的・計画など)果たす、遂げる。実施/施行する
- 関
- act, action, affect, efficacy, impact, impinge, indication, influence, potency, effected
[★]
- 関
- cryptic、negatively、negativity
[★]
- (生理)(薬が)(特に心臓の)筋肉の収縮に影響を与える、変力の、変力性の
[★]
- 関
- effect