English Journal

Inductive potential of recombinant human granulocyte colony-stimulating factor to mature neutrophils from x-irradiated human peripheral blood hematopoietic progenitor cells.

Katsumori T, Yoshino H, Hayashi M, Takahashi K, Kashiwakura I.SourceDepartment of Radiological Life Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho,Hirosaki, Aomori 036-8564, Japan.
Biological & pharmaceutical bulletin.Biol Pharm Bull.2009 Nov;32(11):1849-53.
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) has been used for treatment of neutropenia. Filgrastim, Nartograstim, and Lenograstim are clinically available in Japan. However, the differences in potential benefit for radiation-induced disorder between these types of rhG-CSFs rema
PMID 19881296

Effect of nartograstim, a recombinant human granulocyte colony-stimulating factor on elastase-induced emphysema in rats.

Yoshimatsu A, Nan-ya K, Miki I.SourcePharmacological Research Laboratories, Kyowa Hakko Kirin Co. Ltd., Shizuoka, Japan.
Arzneimittel-Forschung.Arzneimittelforschung.2009;59(5):248-53.
Granulocyte colony-stimulating factor (G-CSF) is known to mobilize stem cells to various organs and that it participates in tissue regeneration. Effect of the recombinant human G-CSF nartograstim (CAS 134088-74-7) was tested on elastase-induced emphysema. Porcine pancreas elastase (PPE) was administ
PMID 19537526

Japanese Journal

Inductive Potential of Recombinant Human Granulocyte Colony-Stimulating Factor to Mature Neutrophils from X-Irradiated Human Peripheral Blood Hematopoietic Progenitor Cells

Katsumori Takeo,Yoshino Hironori,Hayashi Masako,Takahashi Kenji,Kashiwakura Ikuo
Biological & Pharmaceutical Bulletin 32(11), 1849-1853, 2009
… Filgrastim, Nartograstim, and Lenograstim are clinically available in Japan. … In conclusion, different types of rhG-CSFs lead to different effects when rhG-CSF is applied to nonirradiated CD34+ cells, though Filgrastim, Nartograstim, and Lenograstim show equal effects on X-irradiated CD34+ cells. …
NAID 130000116956

倉本加代,青山隆夫,杉浦宗敏,清野敏一,山田安彦,伊賀立二
医療薬学 29(6), 691-697, 2003-12-10
… We studied the adsorption of nartograstim (NT), a recombinant human granulocyte colony-stimulating factor, to a 20mL plastic syringe made of polypropylene, and the actual dose of NT through an extension tube and infusion set from a syringe filled NT solution. … in the description of the package insert of nartograstim (Neu-up^<[○!R]>). …
NAID 110001166752