myocardial contractility

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  • Myocardial effects of local shock wave therapy in a Langendorff model.
  • Becker M, Goetzenich A, Roehl AB, Huebel C, de la Fuente M, Dietz-Laursonn K, Radermacher K, Rossaint R, Hein M.SourceMedical Clinic of Cardiology and Pulmonology, RWTH Aachen University Hospital, Pauwelstrasse 30, 52074 Aachen, Germany.
  • Ultrasonics.Ultrasonics.2014 Jan;54(1):131-6. doi: 10.1016/j.ultras.2013.07.005. Epub 2013 Jul 12.
  • OBJECTIVE: Applying shock waves to the heart has been reported to stimulate the heart and alter cardiac function. We hypothesized that shock waves could be used to diagnose regional viability.METHOD: We used a Langendorff model to investigate the acute effects of shock waves at different energy leve
  • PMID 23896623
  • Lipoteichoic acid from Staphylococcus aureus directly affects cardiomyocyte contractility and calcium transients.
  • Mutig N, Geers-Knoerr C, Piep B, Pahuja A, Vogt PM, Brenner B, Niederbichler AD, Kraft T.SourceInstitute of Molecular and Cell Physiology, Hannover Medical School, Germany.
  • Molecular immunology.Mol Immunol.2013 Dec 31;56(4):720-8. doi: 10.1016/j.molimm.2013.07.007. Epub 2013 Aug 7.
  • Lipoteichoic acid (LTA) is the key pathogenic factor of gram-positive bacteria and contributes significantly to organ dysfunction in sepsis, a frequent complication in critical care patients. We hypothesized that LTA directly affects cardiomyocyte function, thus contributing to cardiac failure in se
  • PMID 23933512


  • Milrinone and levosimendan administered after reperfusion improve myocardial stunning in swine
  • Shibata Itsuko,Cho Sungsam,Yoshitomi Osamu,Ureshino Hiroyuki,Maekawa Takuji,Hara Tetsuya,Sumikawa Koji
  • Scandinavian Cardiovascular Journal 47(1), 50-57, 2013-02
  • … We assessed the effect of milrinone application timing after reperfusion against myocardial stunning as compared with levosimendan in swine. … Regional myocardial contractility was assessed by percent segment shortening (%SS). … Milrinone should be administered just after reperfusion to protect myocardial stunning through p38 MAPK, whereas levosimendan improvement of contractile function could be mainly dependent on its positive inotropic effect. …
  • NAID 120005230617
  • 20-Hydroxyeicosatetraenoic Acid Mediates Isolated Heart Ischemia/Reperfusion Injury by Increasing NADPH Oxidase-Derived Reactive Oxygen Species Production
  • Han Yong,Zhao Huiying,Tang Hong,Li Xinyu,Tan Jiang,Zeng Qinghua,Sun Chengwen
  • Circulation Journal 77(7), 1807-1816, 2013
  • … Background: It has been reported that 20-hydroxyeicosatetraenoic acid (20-HETE) aggravates myocardial ischemia/reperfusion (I/R) injury, but the exact mechanism of action is still unclear. … Perfusion with HET0016, an inhibitor of 20-HETE production, significantly improved I/R-induced reduction in cardiac contractility, myocardial infarction, and myocardial apoptosis. …
  • NAID 130003361743


Myocardial contractility represents the intrinsic ability of the heart/myocardium to contract. Changes in the ability to produce force during contraction result from incremental degrees of binding between myosin (thick) and actin (thin) filaments.
myocardial /myo·car·di·al/ (-kahr´de-al) pertaining to the muscular tissue of the heart. myocardial. See myocardium. myocardial [mi″o-kahr´de-al]. pertaining to the muscular tissue of the heart (the myocardium). myocardial infarction (MI) death ...






myocardial contractilitycardiac contractility



WordNet   license wordnet

「the capability or quality of shrinking or contracting, especially by muscle fibers and even some other forms of living matter」



  • adj.
  • 心筋の
cardiac muscleheart musclemyocardiamyocardium

WordNet   license wordnet

「of or relating to the myocardium」



  • np.
cardiac muscleheart musclemyocardialmyocardium