WordNet

small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
an ancestor in the direct line (同)primogenitor
of or relating to the spinal cord
of or relating to bone marrow

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(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
(人・動植物の)先祖 / 創始者,先駆者

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/04 14:12:48」(JST)

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CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are multipotential progenitor cells.^[1]^[2] "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte.^[3]

CFU-GEMM gives rise to CFU-GM.

It has been suggested that eosinophils do not derive from the common myeloid progenitor in humans.^[4]

References

^ Carow CE, Hangoc G, Broxmeyer HE (February 1993). "Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma". Blood 81 (4): 942–9. PMID 7679010.
^ Roodman GD, LeMaistre CF, Clark GM, Page CP, Newcomb TF, Knight WA (August 1987). "CFU-GEMM correlate with neutrophil and platelet recovery in patients receiving autologous marrow transplantation after high-dose melphalan chemotherapy". Bone Marrow Transplant. 2 (2): 165–73. PMID 3332164.
^ "Hem I WBC Morphology and Physiology". Retrieved 2008-12-30. ^{[dead link]}
^ Mori Y, Iwasaki H, Kohno K et al. (January 2009). "Identification of the human eosinophil lineage-committed progenitor: revision of phenotypic definition of the human common myeloid progenitor". J. Exp. Med. 206 (1): 183–93. doi:10.1084/jem.20081756. PMC 2626675. PMID 19114669.

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1. 急性骨髄性白血病の病因 pathogenesis of acute myeloid leukemia
2. 造血細胞移植のドナーの評価 evaluation of the hematopoietic cell transplantation donor
3. 急性骨髄性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of acute myeloid leukemia
4. 造血腫瘍の分類 classification of the hematopoietic neoplasms
5. 造血細胞移植のためのドナー選定 donor selection for hematopoietic cell transplantation

English Journal

ERK5 pathway regulates transcription factors important for monocytic differentiation of human myeloid leukemia cells.

Wang X1, Pesakhov S, Harrison JS, Danilenko M, Studzinski GP.
Journal of cellular physiology.J Cell Physiol.2014 Jul;229(7):856-67. doi: 10.1002/jcp.24513.
Mitogen-activated protein kinases (MAPKs) are important transducers of external signals for cell growth, survival, and other cellular responses including cell differentiation. Several MAPK cascades are known with the MEK1/2-ERK1/2, JNK, and p38MAPKs receiving most attention, but the role of MEK5-ERK
PMID 24264602

Re-establishment of Anxiety in Stress-Sensitized Mice Is Caused by Monocyte Trafficking from the Spleen to the Brain.

Wohleb ES1, McKim DB1, Shea DT2, Powell ND2, Tarr AJ2, Sheridan JF3, Godbout JP4.
Biological psychiatry.Biol Psychiatry.2014 Jun 15;75(12):970-81. doi: 10.1016/j.biopsych.2013.11.029. Epub 2013 Dec 10.
BACKGROUND: Persistent anxiety-like symptoms may have an inflammatory-related pathophysiology. Our previous work using repeated social defeat (RSD) in mice showed that recruitment of peripheral myeloid cells to the brain is required for the development of anxiety. Here, we aimed to determine if 1) R
PMID 24439304

The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells.

Rothe K1, Lin H2, Lin KB3, Leung A4, Wang HM3, Malekesmaeili M3, Brinkman RR3, Forrest DL5, Gorski SM6, Jiang X7.
Blood.Blood.2014 Jun 5;123(23):3622-34. doi: 10.1182/blood-2013-07-516807. Epub 2014 Apr 22.
Previous studies demonstrated that imatinib mesylate (IM) induces autophagy in chronic myeloid leukemia (CML) and that this process is critical to cell survival upon therapy. However, it is not known if the autophagic process differs at basal levels between CML patients and healthy individuals and i
PMID 24755409

Japanese Journal

Il-27 together with stem cell factor induces differentiation of bone marrow cells into myeloid progenitor cells and expands them

角田廉,溝口出,樋口要,善本隆之,久田将之,粕谷和彦,土田明彦,水口純一郎
東京医科大学雑誌 71(4), 442, 2013-10-30
NAID 120005355423

Establishment and characterization of a novel cell line (HATAK) derived from natural killer cell neoplasm corresponding to the myeloid/NK progenitor

Katayama Takuji,Danbara Mikio,Aoki Takumi [他]
The Kitasato medical journal 43(1), 38-48, 2013-03
NAID 40019619599

In Vivo Deficiency of Both C/EBPβ and C/EBPε Results in Highly Defective Myeloid Differentiation and Lack of Cytokine Response

Akagi Tadayuki,Thoennissen Nils H.,George Ann,Crooks Gay,Song Jee Hoon,Okamoto Ryoko,Nowak Daniel,Gombart Adrian F.,Koeffler H. Phillip
PLoS ONE 5(11), e15419, 2010
… The CCAAT/enhancer binding proteins (C/EBPs) are transcription factors involved in hematopoietic cell development and induction of several inflammatory mediators. … Morphologically, their neutrophils were blocked at the myelocytes/metamyelocytes stage, and clonogenic assays of bone marrow cells indicated a significant decrease in the number of myeloid colonies of the bbee mice. …
NAID 120002647977