WordNet

an immature leukocyte normally found in bone marrow
small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
of or relating to the spinal cord
of or relating to bone marrow

PrepTutorEJDIC

(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/16 21:51:10」(JST)

wiki en

[Wiki en表示]

Basophilic^[1]

Eosinophilic^[2]

Neutrophilic^[3]

A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).

Histology

When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells.

Numerous cytoplasmic granules are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules are peroxidase-positive, while basophilic granules are not.

The nuclear chromatin is coarser than that observed in myelocyte, but it is relatively faintly stained and lacks a well defined membrane.

The nucleus is fairly regular in contour (not indented), and seems to be 'buried' beneath the numerous cytoplasmic granules. (If the nucleus were indented, it would likely be a metamyelocyte.)

Maturation

Myelocytes are derived from promyelocytes and give rise to metamyelocytes.

Measurement

There is an internationally agreed method of counting blasts, with results from M1 upwards.

Additional images

Hematopoiesis

References

^ Histology image:01809loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.
^ Histology image:01810loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.
^ Histology image:01804loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732.

External links

Neutrophilic Myelocyte Presented by the University of Virginia
Eosinophilic Myelocyte Presented by the University of Virginia
Basophilic Myelocyte Presented by the University of Virginia
Image at queensu.ca

This cell biology article is a stub. You can help Wikipedia by expanding it.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 急性骨髄性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of acute myeloid leukemia
2. 慢性骨髄性白血病における造血細胞移植 hematopoietic cell transplantation in chronic myeloid leukemia
3. 造血腫瘍の分類 classification of the hematopoietic neoplasms
4. 芽球性形質細胞様樹状細胞腫瘍 blastic plasmacytoid dendritic cell neoplasm
5. Eosinophil biology and causes of eosinophilia

English Journal

Recruitment of circulating dendritic cell precursors into the infarcted myocardium and pro-inflammatory response in acute myocardial infarction.

Kretzschmar D, Betge S, Windisch A, Pistulli R, Rohm I, Fritzenwanger M, Jung C, Schubert K, Theis B, Petersen I, Drobnik S, Mall G, Figulla HR, Yilmaz A.Source*Department of Internal Medicine I, Division of Cardiology and Intensive Care Medicine, University Hospital Jena, Jena, Germany.
Clinical science (London, England : 1979).Clin Sci (Lond).2012 Sep 1;123(6):387-98.
DC (dendritic cells) play an important role in the immune system. They invade peripheral tissues to detect harmful antigens, inducing a local immune response. Studies suggest that DCPs (dendritic cell precursors) might be reduced in AMI (acute myocardial infarction); however, the reason for their re
PMID 22494099

Restoration of adipose function in obese glucose-tolerant men following pioglitazone treatment is associated with CCAAT enhancer-binding protein β up-regulation.

Powell LA, Crowe P, Kankara C, McPeake J, McCance DR, Young IS, Trimble ER, McGinty A.SourceNutrition and Metabolism Group, Centre for Public Health, Queen's University Belfast, and Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, UK.
Clinical science (London, England : 1979).Clin Sci (Lond).2012 Aug 1;123(3):135-46.
Obese AT (adipose tissue) exhibits increased macrophage number. Pro-inflammatory CD16+ peripheral monocyte numbers are also reported to increase with obesity. The present study was undertaken to simultaneously investigate obesity-associated changes in CD16+ monocytes and ATMs (AT macrophages). In ad
PMID 22309242

Japanese Journal

Cross-priming of CD8(+) T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia.

Kitawaki Toshio,Kadowaki Norimitsu,Fukunaga Keiko,Kasai Yasunari,Maekawa Taira,Ohmori Katsuyuki,Itoh Tatsuya,Shimizu Akira,Kuzushima Kiyotaka,Kondo Tadakazu,Ishikawa Takayuki,Uchiyama Takashi
Experimental hematology 39(4), 424-433.e2, 2011-04
… The prognosis for elderly patients with acute myeloid leukemia (AML) remains dismal. … To explore the potential of immunotherapy for improving clinical outcomes for these patients, we performed a phase I clinical trial of dendritic cell (DC)-based immunotherapy for elderly patients with AML. …
NAID 120002970837

Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2

Sawahata Ryoko,Shime Hiroaki,Yamazaki Sayuri,Inoue Norimitsu,Akazawa Takashi,Fujimoto Yukari,Fukase Koichi,Matsumoto Misako,Seya Tsukasa
Microbes and Infection 13(4), 350-358, 2011-04
… TLR2 is known to mature myeloid dendritic cells (mDC) to drive mDC contact-mediated natural killer (NK) cell activation. … Pam2CSK4 and MALP-2 have the common lipid moiety but different peptides, which are crucial for NK cell activation. …
NAID 120002912001

Related Pictures

★リンクテーブル★

リンク元	「myelocytic」「骨髄系細胞」「骨髄球系細胞」「ミエロイド細胞」「bone marrow cell」
関連記事	「myeloid」「myelo」「cell」