UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 肥大型心筋症における流出路閉塞の非薬理学的治療 nonpharmacologic treatment of outflow obstruction in hypertrophic cardiomyopathy
2. 特殊な問題の治療を含む肥大型心筋症管理の概要 overview of hypertrophic cardiomyopathy management including treatment of special problems
3. 患者情報：肥大型心筋症（詳細） hypertrophic cardiomyopathy beyond the basics

English Journal

Left Ventricular Outflow Tract Obstruction in Hypertrophic Cardiomyopathy Patients Without Severe Septal Hypertrophy: Implications of Mitral Valve and Papillary Muscle Abnormalities Assessed Using Cardiac Magnetic Resonance and Echocardiography.

Patel P1, Dhillon A1, Popovic ZB1, Smedira NG1, Rizzo J1, Thamilarasan M1, Agler D1, Lytle BW1, Lever HM1, Desai MY2.
Circulation. Cardiovascular imaging.Circ Cardiovasc Imaging.2015 Jul;8(7):e003132. doi: 10.1161/CIRCIMAGING.115.003132.
BACKGROUND: In patients with hypertrophic cardiomyopathy and left ventricular outflow tract (LVOT) obstruction, but without basal septal hypertrophy, we sought to identify mitral valve (MV) and papillary muscle (PM) abnormalities that predisposed to LVOT obstruction, using echo and cardiac magnetic
PMID 26082555

Involvement of the -420C>G RETN polymorphism in myocardial fibrosis in patients with hypertrophic cardiomyopathy.

Hernández-Romero D1,2, Orenes-Piñero E1,2, García-Honrubia A3, Climent V4, Romero-Aniorte AI1,2, Martínez CM2,5, García-Bautista M6, Martínez M4, Feliu E4, González J1,2, Cánovas S1, Montero-Argudo JA7, Valdés M1,2, Marín F1,2.
Journal of internal medicine.J Intern Med.2015 Jul;278(1):50-8. doi: 10.1111/joim.12334. Epub 2015 Jan 5.
AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy and fibrosis. HCM is an autosomal-dominant disease caused by more than 400 mutations in sarcomeric genes. Changes in nonsarcomeric genes contribute to its phenotypic heterogeneity. Cardiac fibrosis can be studie
PMID 25476756

Al Maluli H1, Mathur M1, Keane MG1, Guy TS2, Dries D1, Edmundowicz D1.
Echocardiography (Mount Kisco, N.Y.).Echocardiography.2015 Jun 8. doi: 10.1111/echo.12989. [Epub ahead of print]
PMID 26059090

瀬尾浩之,藤井弘通,青山孝信,笹子佳門
日本心臓血管外科学会雑誌 44(2), 92-96, 2015
症例は72歳の男性．閉塞性肥大型心筋症と診断され，4年間，薬物加療が行われていたが，労作時倦怠感および呼吸苦が出現した．心エコー検査では，全周性の心筋肥大と左室中部から流出路における狭窄病変を認め，同部位での最大圧較差は94 mmHgと増悪していた．また，前乳頭筋が著明に肥大して前方に偏位しており，同乳頭筋から僧帽弁前尖へ付着する腱索が著明に短縮しtetheringを認めていた．収縮期には，肥大し …
NAID 130005062373

Concomitant Septal Myectomy in Patients Undergoing Aortic Valve Replacement for Severe Aortic Stenosis

Lim Ju Yong,Choi Jin Oh,Oh Jae Kon [他],Li Zhou,Park Soon J.
Circulation Journal 79(2), 375-380, 2015
… With low sensitivity of echocardiography for detecting dynamic left ventricular outflow tract (LVOT) obstruction in severe AS, we adopted a routine intraoperative inspection of LVOT strategy for aortic valve replacement (AVR), and performed concomitant septal myectomy (CSM) as necessary. …
NAID 130004927041