mycophenolic acid

出典: meddic

ミコフェノール酸 MPA

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/05/12 22:44:50」(JST)

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  • Circadian variation of mycophenolate mofetil pharmacokinetics in rats.
  • Dridi I1, Ben-Cherif W2, Aouam K3, Ben-Attia M4, Klouz A5, Reinberg A6, Boughattas NA7.
  • European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2014 Jul 16;58:20-5. doi: 10.1016/j.ejps.2014.02.015. Epub 2014 Mar 19.
  • The present work aims to investigate whether the pharmacokinetics of the active metabolite mycophenolic acid (MPA) varies according to the circadian dosing-time of mycophenolate mofetil (MMF). A total of 180 male Wistar rats aged 8 weeks and synchronized for 3weeks to 12h light and 12h dark were use
  • PMID 24657835
  • Characterization of the Zebrafish Ugt Repertoire Reveals a New Class of Drug-Metabolizing UDP Glucuronosyltransferases.
  • Wang Y1, Huang H1, Wu Q2.
  • Molecular pharmacology.Mol Pharmacol.2014 Jul;86(1):62-75. doi: 10.1124/mol.113.091462. Epub 2014 Apr 11.
  • The zebrafish genome contains a gene superfamily of 40 Ugt genes that can be divided into Ugt1, Ugt2, and Ugt5 families. Because the encoded zebrafish UDP glucuronosyltransferase (UGT) proteins do not display orthologous relationships to any of the mammalian and avian UGT enzymes based on molecular
  • PMID 24728488
  • Long-term dosing patterns of enteric-coated mycophenolate sodium or mycophenolate mofetil with tacrolimus after renal transplantation.
  • Langone A1, Shihab F, Pankewycz O, Doria C, Wiland A, McCague K, Chan L.
  • Clinical transplantation.Clin Transplant.2014 Jun 4. doi: 10.1111/ctr.12392. [Epub ahead of print]
  • MORE was a four-year, prospective, observational study at 40 transplant centers in the US. Data were analyzed to evaluate changes in MPA dosing over time in 904 de novo kidney transplant recipients receiving enteric-coated mycophenolate sodium (EC-MPS, n=616) or mycophenolate mofetil (MMF, n=288) wi
  • PMID 24893821


  • ABO 血液型不適合腎移植患者における個別医療の可能性:脱感作療法開始時および移植直前の免疫抑制薬感受性モニタリングから
  • 杉山 健太郎,笹原 浩康,磯貝 和也,塚口 真穂登,外山 聡,佐藤 博,齋藤 和英,中川 由紀,高橋 公太,田中 祥子,恩田 健二,平野 俊彦
  • Organ Biology 21(2), 182-186, 2014
  • … Therefore, we evaluated pharmacological efficacies of tacrolimus(Tac), cyclosporine(CyA), and mycophenolic acid(MPA)by LIST, as well as ATP amounts in peripheral blood mononuclear cells(PBMCs)of patient origin, at both the beginning of desensitization immunosuppressive therapy and just before renal transplant operation. …
  • NAID 130004715802
  • Glucuronidation and Subsequent Biliary Excretion of Mycophenolic Acid in Rat Sandwich-cultured Hepatocytes
  • , , ,
  • Drug Metabolism and Pharmacokinetics 29(2), 129-134, 2014
  • …   Rat sandwich-cultured hepatocytes (SCH) were used to correlate the in vitro hepatic disposition of mycophenolic acid (MPA) with published in vivo data, as well as mechanistic studies on drug-drug interaction. …
  • NAID 130004463363
  • Optimization of Mycophenolic Acid Therapy Using Clinical Pharmacometrics
  • , ,
  • Drug Metabolism and Pharmacokinetics 29(1), 4-11, 2014
  • … For narrow therapeutic index drugs such as mycophenolic acid (MPA) which exhibit large inter-individual variation in drug exposure, pharmacometric analysis can be of great clinical benefit. …
  • NAID 130004463351


[Mycophenolic Acid] [24280-93-1] | 価格や在庫、物性値などの詳細情報ページです。 ... 絵表示 注意喚起語 警告 危険有害性情報 H302:飲み込むと有害 注意書き P264:取扱い後はよく手を洗うこと。 P270:この製品を使用する時に、飲食 ...
Mycophenolic Acid Acyl-b-D-glucuronide 製品名称: Mycophenolic Acid Acyl-b-D-glucuronide CAS登録番号: 99043-04-6 シノニム: 1-[(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-1 ...


Mycophenolic acidMYCOPHENOLIC ACIDFile:Mycophenolic acid Strucrural Formulae Mofilet-S (Mycophenolic Acid) - 360mg (60 Mycophenolic acidMycophenolic acid Chemical Structure




cytotoxic agent cytotoxic agents, cytotoxic drug
  • 免疫抑制にも使われるし、抗腫瘍化学治療薬にも使われる


  • antimetabolites
  • alkylating agents





mycophenolic acid, mycophenolate, MPA



WordNet   license wordnet

「street name for lysergic acid diethylamide」
back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen

WordNet   license wordnet

「any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt」

WordNet   license wordnet

「having the characteristics of an acid; "an acid reaction"」

PrepTutorEJDIC   license prepejdic

「酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD」