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having or involving or consisting of more than one part or entity or individual; "multiple birth"; "multiple ownership"; "made multiple copies of the speech"; "his multiple achievements in public life"; "her multiple personalities"; "a pineapple is a multiple fruit"
the product of a quantity by an integer; "36 is a multiple of 9"
a blank gap or missing part (同)blank

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1. ラクナ梗塞 lacunar infarcts
2. 脳卒中評価の概要 overview of the evaluation of stroke
3. パーキンソン病の診断 diagnosis of parkinson disease
4. 皮質下梗塞および白質脳症を伴う常染色体優性脳動脈症（CADASIL） cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy cadasil
5. 脳血管性認知症の病因、臨床症状、および診断 etiology clinical manifestations and diagnosis of vascular dementia

Metabolic Syndrome Is a Risk Factor for Acute Cerebral Infarction in a Younger Elderly Kurashiki Population.

Ohta Y, Takao Y, Harada K, Takehisa Y, Takao T, Abe K.SourceDepartment of Neurology, Kurashiki-Heisei Hospital, Okayama, Japan; Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2012 Apr;21(3):231-239. Epub 2010 Sep 19.
This study evaluated the association between metabolic syndrome as defined by Japanese criteria and its diagnostic components (visceral obesity, dyslipidemia, hypertension, and impaired glucose tolerance) and acute cerebral infarction in younger elderly (age 50-74 years) and the older elderly (age �
PMID 20851624

Chutinet A, Biffi A, Kanakis A, Fitzpatrick KM, Furie KL, Rost NS.SourceJ. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts; and Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
AJNR. American journal of neuroradiology.AJNR Am J Neuroradiol.2012 Mar 15. [Epub ahead of print]
BACKGROUND AND PURPOSE: The severity of white matter hyperintensity, or leukoaraiosis, is a marker of cerebrovascular disease. In stroke, WMH burden is strongly linked to lacunar infarction; however, impaired cerebral perfusion due to extracranial or intracranial atherosclerosis may also contribute
PMID 22422177

Efficacy of the Free Radical Scavenger, Edaravone, for Motor Palsy of Acute Lacunar Infarction

Ohta Yasuyuki,Takamatsu Kazuhiro,Fukushima Tomoko,Ikegami Satomi,Takeda Ikuko,Ota Taisei,Goto Katsuya,Abe Koji
Internal Medicine 48(8), 593-596, 2009
… Objective Free radicals are important in causing neural cell injury during cerebral infarction. … Although there was a randomized, placebo-controlled, double-blind study at multiple centers in Japan showing the efficacy of the free radical scavenger, edaravone, in acute cerebral infarction, to date the clinical studies are few. … This study investigated the effect of edaravone on the outcome of patients with acute lacunar infarction. …
NAID 130000108032

古村慎二,尾崎裕
順天堂医学 54(2), 158-165, 2008-06
目的:画像解析ソフトウェアを用いた客観的評価法により,多発性硬化症の脱髄斑辺緑部に認められる高信号帯hyperintense rimと周囲白質との信号差を検討する.また多発性硬化症とラクナ梗塞におけるhyperintense rimの出現頻度を比較検討する.対象と方法:2006年2月から2007年7月にMRI検査が施行され,T1強調像で結節状低信号を呈する多発性硬化症39症例239病変とラクナ梗塞 …
NAID 110007125299