WordNet

an infection caused by fungi of the genus Monilia or Candida (especially Candida albicans) (同)moniliasis, monilia disease
of or relating to mucous membranes

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1. 口腔咽頭および食道カンジダ症の治療 treatment of oropharyngeal and esophageal candidiasis
2. 口腔咽頭および食道カンジダ症の臨床症状 clinical manifestations of oropharyngeal and esophageal candidiasis
3. カンジダ感染症の概要 overview of candida infections
4. 口腔病変 oral lesions
5. 小児における口腔軟部組織病変 soft tissue lesions of the oral cavity in children

English Journal

NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response.

Ibrahim AS, Luo G, Gebremariam T, Lee H, Schmidt CS, Hennessey JP Jr, French SW, Yeaman MR, Filler SG, Edwards JE Jr.SourceThe Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California Los Angeles (UCLA) Medical Center and the St. John's Cardiovascular Research Center, Torrance, CA, United States; David Geffen School of Medicine at UCLA, Los Angeles, CA, United States. Electronic address: ibrahim@labiomed.org.
Vaccine.Vaccine.2013 Nov 12;31(47):5549-56. doi: 10.1016/j.vaccine.2013.09.016. Epub 2013 Sep 21.
We have previously reported that vaccination with rAls3p-N protein of Candida albicans, formulated with alum adjuvant (also designated as NDV-3) protects immunocompetent mice from, lethal disseminated candidiasis and mucosal oropharyngeal candidiasis. NDV-3 vaccine was recently, tested in a Phase 1
PMID 24063977

A rare cause of dysphagia in a HIV patient--esophageal pseudodiverticulosis.

Krishnamoorthi R, Nandagopal L, Ehrinpreis M.SourceDepartment of Internal Medicine, Division of Gastroenterology, Wayne State University, Detroit, Michigan 48201, USA. rkrishn@med.wayne.edu
Acta gastro-enterologica Belgica.Acta Gastroenterol Belg.2013 Sep;76(3):340-1.
Esophageal pseudodiverticulosis is a rare clinical entity with a slight male predominance (1). The condition is caused by cystic dilation of the sub mucosal glands and hence is not true diverticulosis. This is usually a benign condition, affecting the distal third of esophagus. It has been associate
PMID 24261030

Bioadhesive vaginal tablets containing spray dried microspheres loaded with clotrimazole for treatment of vaginal Candidiasis.

Gupta NV, Natasha S, Getyala A, Bhat RS.AbstractThe aim of the present investigation was to prepare and evaluate novel bioadhesive vaginal tablets containing clotrimazole loaded microspheres in order to provide long-term therapeutic activity at the site of infection. Tablets were prepared by incorporating drug loaded microspheres and using bioadhesive polymers hydroxypropylmethylcellulose, sodium carboxymethylcellulose and Carbopol. Microspheres were prepared by the spray drying technique using Eudragit RS-100 and Eudragit RL-100. Microspheres were characterized by SEM, DSC, FTIR, particle size analysis and evaluated for percentage yield, drug loading, encapsulation efficiency and in vitro drug release. To achieve bioadhesion to the mucosal tissue, optimized microspheres were incorporated into bioadhesive tablets and were evaluated for in vitro drug release, in vitro and in vivo mucoadhesion. FTIR and DSC studies showed that no chemical interaction occurred between the drug and polymers. The sphericity factor indicated that the prepared microspheres were spherical. Formulation Mt6 indicated a controlled in vitro drug release and good bioadhesive strength. The in vivo images confirmed the bioadhesion and retention property of tablets up to 24 h. The results indicated that this drug delivery system can be explored for controlled intravaginal drug release.
Acta pharmaceutica (Zagreb, Croatia).Acta Pharm.2013 Sep;63(3):359-72. doi: 10.2478/acph-2013-0027.
The aim of the present investigation was to prepare and evaluate novel bioadhesive vaginal tablets containing clotrimazole loaded microspheres in order to provide long-term therapeutic activity at the site of infection. Tablets were prepared by incorporating drug loaded microspheres and using bioadh
PMID 24152896

Japanese Journal

腸管内酵母としてのカンジダと健康保持 : 生物進化的考察

安部茂,羽山和美,丸山奈保 [他]
Medical mycology research 4(1), 11-23, 2013
NAID 40020058037

The Essential Oil of Melaleuca alternifolia (Tea Tree Oil) and Its Main Component, Terpinen-4-ol Protect Mice from Experimental Oral Candidiasis

Ninomiya Kentaro,Maruyama Naho,Inoue Shigeharu [他],Ishibashi Hiroko,Takizawa Toshio,Oshima Haruyuki,Abe Shigeru
Biological and Pharmaceutical Bulletin 35(6), 861-865, 2012
… The therapeutic efficacy of tea tree oil (TTO), Melaleuca alternifolia, and its main component, terpinen-4-ol, were evaluated in a murine oral candidiasis model. … Prednisolone -pretreated mice were orally infected with a fluconazole-susceptible (TIMM 2640) or a resistant (TIMM 3163) strain of Candida albicans to induce oral candidiasis. … Even against oral candidiasis caused by azole-resistant C. …
NAID 130001872166

口腔粘膜疾患治療用超音波チップの振動モード解析と試作

青柳学,村上有二
電子情報通信学会技術研究報告. US, 超音波 111(311), 5-9, 2011-11-17
口腔カンジダ症や黒毛舌などの口腔粘膜疾患の治療には超音波チップによる偽膜,舌毛の除去が有効であることが臨床的に実証されている.使用した超音波治療器具は歯科治療用超音波スケーラチップの形状をスプーン状に加工したものである.しかし,このチップ形状が口内粘膜疾患治療に有効である理由や振動系に与える影響が不明であった.また,振動系の変化のため,超音波治療装置での励振レベルの低下が生じた.したがって,励振効 …
NAID 110009465576