7モノソミー
WordNet
- chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number
UpToDate Contents
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English Journal
- Impact of Additional Cytogenetic Abnormalities in Adults with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation.
- Aldoss I1, Stiller T2, Cao TM3, Palmer JM2, Thomas SH3, Forman SJ3, Pullarkat V3.
- Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.Biol Blood Marrow Transplant.2015 Jul;21(7):1326-9. doi: 10.1016/j.bbmt.2015.03.021. Epub 2015 Apr 1.
- The occurrence of additional cytogenetic abnormalities (ACAs) is common in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) but is of unknown significance in the tyrosine kinase inhibitor (TKI) era. We retrospectively analyzed data from a consecutive case series of adults with
- PMID 25842050
- Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia.
- de Rooij JD1, Beuling E1, van den Heuvel-Eibrink MM1, Obulkasim A1, Baruchel A2, Trka J3, Reinhardt D4, Sonneveld E5, Gibson BE6, Pieters R7, Zimmermann M4, Zwaan CM1, Fornerod M8.
- Haematologica.Haematologica.2015 Jun 11. pii: haematol.2015.124321. [Epub ahead of print]
- IKAROS family zinc finger 1/IKZF1 is a transcription factor important in lymphoid differentiation, and a known tumor suppressor in acute lymphoid leukemia. Recent studies suggest that IKZF1 is also involved in myeloid differentiation. To investigate whether IKZF1 deletions also play a role in pediat
- PMID 26069293
- The applicability of the WHO classification in paediatric AML. A NOPHO-AML study.
- Sandahl JD1, Kjeldsen E2, Abrahamsson J3, Ha SY4, Heldrup J5, Jahnukainen K6, Jónsson ÓG7, Lausen B8, Palle J9, Zeller B10, Forestier E11, Hasle H1.
- British journal of haematology.Br J Haematol.2015 Jun;169(6):859-67. doi: 10.1111/bjh.13366. Epub 2015 Mar 29.
- The World Health Organization (WHO) classification of myeloid leukaemia was revised in 2008. It incorporates newly recognized entities and emphasizes the pivotal role of cytogenetic abnormalities. The aim of this study was to evaluate the usability of the WHO classification when applied to a large p
- PMID 25819835
Japanese Journal
- モノソミー7を伴うAML/MDSのモデルマウスの作製 (第54回原子爆弾後障害研究会特集号)
- 加藤 大貴,古川 博雄,新美 照幸 [他]
- 日本口腔外科学会雑誌 = Japanese journal of oral and maxillofacial surgery 60(3), 147-150, 2014-03
- NAID 40020048123
Related Links
- モノソミー7 Monosomy 7 白血病細胞の7番染色体が1本しかないものをいう。この型は骨髄異形成症候群から移行したものに多く、通常の化学療法のみでは予後は不良といわれており、造血幹細胞移植の適応と考えられている。
- Results of a German study indicate that Dacogen and Vidaza may improve the survival of myelodysplastic syndromes patients with the chromosomal abnormality monosomy 7. Specifically, the researchers found that myelodysplastic ...
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- 英
- monosomy 7
- 関
- 7番染色体