monooctanoin

Monoctanoin
Systematic (IUPAC) name
	2,3-Dihydroxypropyl octanoate
Identifiers
CAS Registry Number	502-54-5
PubChem	CID: 3033877
ChemSpider	2298454
UNII	VFU0OU98LO
Synonyms	1-Mono-octanoin; Glycerol monoctanoate; 1-Monocaprylin; 1-Monocapryloyl-rac-glycerol; 1-Monooctanoin; 1-Monooctanoylglycerol; Caprylic acid α-monoglyceride; DL-1-Monooctanoin; Glyceryl 1-monooctanoate; Octanoic acid 1-monoglyceride; α-Monocaprylin
Chemical data
Formula	C11H22O4
Molecular mass	218.29 g/mol
	SMILES O=C(OCC(O)CO)CCCCCCC ;
	InChI InChI=1S/C11H22O4/c1-2-3-4-5-6-7-11(14)15-9-10(13)8-12/h10,12-13H,2-9H2,1H3 ; Key:GHBFNMLVSPCDGN-UHFFFAOYSA-N ;

CAS Type 1 Name octanoic acid, monoester with 1,2,3-propanetriol
Equivalent Terms Capmul; Capmul 8210; Moctanin; glycerol-1-monooctanoate; glyceryl-1-monooctanoate; mono-octanoin; monocaprylin; monoctanoin
CAS Registry Number 26402-26-6
胆石の溶解に使われるらしい？
胆嚢直接溶解薬

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/22 04:12:41」(JST)

Solid self-nanoemulsifying drug delivery system (S-SNEDDS) of darunavir for improved dissolution and oral bioavailability: In vitro and in vivo evaluation.

Inugala S1, Eedara BB1, Sunkavalli S1, Dhurke R1, Kandadi P1, Jukanti R1, Bandari S2.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2015 Jul 10;74:1-10. doi: 10.1016/j.ejps.2015.03.024. Epub 2015 Apr 3.
The current study was aimed to investigate the potential of solid self-nanoemulsifying drug delivery system (S-SNEDDS) composed of Capmul MCM C8 (oil), Tween 80 (surfactant) and Transcutol P (co-surfactant) in improving the dissolution and oral bioavailability of darunavir. Liquid self-nanoemulsifyi
PMID 25845633

Cellular interactions and photoprotective effects of idebenone-loaded nanostructured lipid carriers stabilized using PEG-free surfactant.

Kyadarkunte AY1, Patole MS2, Pokharkar VB3.
International journal of pharmaceutics.Int J Pharm.2015 Feb 1;479(1):77-87. doi: 10.1016/j.ijpharm.2014.12.044. Epub 2014 Dec 26.
In past years, nanostructured lipid carriers (NLCs) have emerged as novel topical antioxidant delivery systems because of combined positive features of liposomes and polymeric nanoparticles. Here, we seek to unlock the possibility of idebenone (IDB; an antioxidant)-loaded NLCs (IDB-NLCs) cellular in
PMID 25545795

Novel semisolid SNEDDS based on PEG-30-di-(polyhydroxystearate): Progesterone incorporation and in vitro digestion.

Hassan TH1, Mäder K2.
International journal of pharmaceutics.Int J Pharm.2015;486(1-2):77-87. doi: 10.1016/j.ijpharm.2015.03.044. Epub 2015 Mar 21.
The aim of this work is to study the digestibility of PEG-30-di-(polyhydroxystearate) (Cithrol(®) DPHS) and its semisolid novel self-nanoemulsifying drug delivery systems (SNEDDS). Furthermore, the SNEDDS-mediated solubility enhancement of the poorly water-soluble drug Progesterone was evaluated in
PMID 25804497

A self-microemulsifying drug delivery system to overcome intestinal resveratrol toxicity and presystemic metabolism.

Seljak KB1, Berginc K, Trontelj J, Zvonar A, Kristl A, Gašperlin M.
Journal of pharmaceutical sciences.J Pharm Sci.2014 Nov;103(11):3491-500. doi: 10.1002/jps.24114. Epub 2014 Aug 7.
A mixed lipid-mixed surfactant self-microemulsifying drug delivery system (SMEDDS) was developed to exploit the health benefits of resveratrol, a Biopharmaceutical Classification System Class 2 natural polyphenol, subject to extensive intestinal presystemic metabolism. SMEDDS with a mixed lipid phas
PMID 25103361