モノシストロニックな、単シストロン性の
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/23 18:14:31」(JST)
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A cistron is a gene.[1] The term cistron is used to emphasize that genes exhibit a specific behavior in a cis-trans test; distinct positions (or loci) within a genome are cistronic.
For example, suppose a mutation at a chromosome position is responsible for a recessive trait in a diploid organism (where chromosomes come in pairs). We say that the mutation is recessive because the organism will exhibit the wild type phenotype (ordinary trait) unless both chromosomes of a pair have the mutation (homozygous mutation). Similarly, suppose a mutation at another position, , is responsible for the same recessive trait. The positions and are said to be within the same cistron when an organism that has the mutation at on one chromosome and has the mutation at position on the paired chromosome exhibits the recessive trait even though the organism is not homozygous for either mutation. When instead the wild type trait is expressed, the positions are said to belong to distinct cistrons / genes.
For example, an operon is a stretch of DNA that is transcribed to create a contiguous segment of RNA, but contains more than one cistron / gene. The operon is said to be polycistronic, whereas ordinary genes are said to be monocistronic.
References
- ^ Lewin, Benjamin (2000). Genes VII. New York: Oxford University Press and Cell Press. p. 955. ISBN 0-19-879276-X.
English Journal
- Genetic basis for metabolism of methylated sulfur compounds in methanosarcina species.
- Fu H1, Metcalf WW2.
- Journal of bacteriology.J Bacteriol.2015 Apr 15;197(8):1515-24. doi: 10.1128/JB.02605-14. Epub 2015 Feb 17.
- Methanosarcina acetivorans uses a variety of methylated sulfur compounds as carbon and energy sources. Previous studies implicated the mtsD, mtsF, and mtsH genes in catabolism of dimethylsulfide, but the genes required for use of other methylsulfides have yet to be established. Here, we show that a
- PMID 25691524
- Copper homeostasis-related genes in three separate transcriptional units regulated by CsoR in Corynebacterium glutamicum.
- Teramoto H1, Yukawa H, Inui M.
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2015 Apr;99(8):3505-17. doi: 10.1007/s00253-015-6373-z. Epub 2015 Jan 16.
- In Corynebacterium glutamicum R, CsoR acts as a transcriptional repressor not only of the cognate copA-csoR operon but also of the copZ1-copB-cgR_0126 operon. It is predicted that copA and copB encode P-type ATPases for copper efflux and copZ1 encodes a metallochaperone. Here, a CsoR-binding motif w
- PMID 25592736
- Trypanosoma brucei RRM1 Is a Nuclear RNA-Binding Protein and Modulator of Chromatin Structure.
- Naguleswaran A1, Gunasekera K1, Schimanski B1, Heller M2, Hemphill A3, Ochsenreiter T1, Roditi I4.
- mBio.MBio.2015 Mar 17;6(2). pii: e00114-15. doi: 10.1128/mBio.00114-15.
- TbRRM1 of Trypanosoma brucei is a nucleoprotein that was previously identified in a search for splicing factors in T. brucei. We show that TbRRM1 associates with mRNAs and with the auxiliary splicing factor polypyrimidine tract-binding protein 2, but not with components of the core spliceosome. TbRR
- PMID 25784696
Japanese Journal
- Molecular characterization and significance of phosphoenolpyruvate carboxykinase in a ruminal bacterium, Streptococcus bovis
- Asanuma Narito,Kanada Kazuhiro,Arai Yusuke,Yoshizawa Kimio,Ichikawa Tatsuya,Hino Tsuneo
- The Journal of General and Applied Microbiology 56(2), 121-127, 2010
- … Transcriptional analysis indicated that the <I>pck </I>is transcribed in a monocistronic fashion. …
- NAID 130004449278
- Expression and Characterization of the Streptomyces coelicolor Serine/Threonine Protein Kinase PkaD
- Urabe Hiroaki,Aoyagi Narumi,Ogawara Hiroshi [他],MOTOJIMA Kiyoto
- Bioscience, biotechnology, and biochemistry 72(3), 778-785, 2008-03-23
- … was transcribed as a monocistronic mRNA, and it was expressed constitutively throughout the life cycle. …
- NAID 10027525712
- Production of a Recombinant Fab in Pichia pastoris from a Monocistronic Expression Vector
- Burtet Rafael Trindade,Santos-Silva Marcos Antonio,Buss Guilherme Antonio Marques [他],MORAES Lidia Maria Pepe,MARANHAO Andrea Queiroz,BRIGIDO Marcelo Macedo
- The journal of biochemistry 142(6), 665-669, 2007-12-01
- NAID 10020094998
Related Links
- Looking for online definition of monocistronic in the Medical Dictionary? monocistronic explanation free. What is monocistronic? Meaning of monocistronic medical term. What does monocistronic mean? Monocistronic | definition of ...
- Germline Expression Influences Operon Organization in the Caenorhabditis... Magazine article from: Genetics ...together along chromosomes in local clusters that also contain monocistronic germline-expressed ...
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