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1. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の臨床的特徴 clinical features of amyotrophic lateral sclerosis and other forms of motor neuron disease
2. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の診断 diagnosis of amyotrophic lateral sclerosis and other forms of motor neuron disease
3. 重症筋無力症の鑑別診断 differential diagnosis of myasthenia gravis
4. 成人における詳細な神経学的検査 the detailed neurologic examination in adults
5. 筋萎縮性側索硬化症の疫学および病因 epidemiology and pathogenesis of amyotrophic lateral sclerosis

SLC10A4 Is a Vesicular Amine-Associated Transporter Modulating Dopamine Homeostasis.

Larhammar M1, Patra K1, Blunder M1, Emilsson L1, Peuckert C1, Arvidsson E1, Rönnlund D2, Preobraschenski J3, Birgner C1, Limbach C1, Widengren J2, Blom H2, Jahn R3, Wallén-Mackenzie Å1, Kullander K4.
Biological psychiatry.Biol Psychiatry.2015 Mar 15;77(6):526-36. doi: 10.1016/j.biopsych.2014.07.017. Epub 2014 Jul 24.
BACKGROUND: The neuromodulatory transmitters, biogenic amines, have profound effects on multiple neurons and are essential for normal behavior and mental health. Here we report that the orphan transporter SLC10A4, which in the brain is exclusively expressed in presynaptic vesicles of monoaminergic a
PMID 25176177

Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder.

Jukic MM1, Carrillo-Roa T2, Bar M1, Becker G1, Jovanovic VM1, Zega K1, Binder EB3, Brodski C1.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.Neuropsychopharmacology.2015 Mar;40(4):839-48. doi: 10.1038/npp.2014.244. Epub 2014 Sep 22.
Subtle mood fluctuations are normal emotional experiences, whereas drastic mood swings can be a manifestation of bipolar disorder (BPD). Despite their importance for normal and pathological behavior, the mechanisms underlying endogenous mood instability are largely unknown. During embryogenesis, the
PMID 25241801

Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates.

Broms J1, Antolin-Fontes B, Tingström A, Ibañez-Tallon I.
The Journal of comparative neurology.J Comp Neurol.2015 Feb 15;523(3):359-80. doi: 10.1002/cne.23664. Epub 2014 Sep 8.
The habenula is a phylogenetically conserved brain structure in the epithalamus. It is a major node in the information flow between fronto-limbic brain regions and monoaminergic brainstem nuclei, and is thus anatomically and functionally ideally positioned to regulate emotional, motivational, and co
PMID 25116430

Chronic Alterations in Monoaminergic Cells in the Locus Coeruleus in Orexin Neuron-Ablated Narcoleptic Mice