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English Journal
- Tubulin inhibitors in non-small cell lung cancer: looking back and forward.
- Ferrara R1, Pilotto S1, Peretti U1, Caccese M1, Kinspergher S1, Carbognin L1, Karachaliou N2, Rosell R2,3,4,5,6, Tortora G1, Bria E1.
- Expert opinion on pharmacotherapy.Expert Opin Pharmacother.2016 Mar 10:1-17. [Epub ahead of print]
- INTRODUCTION: Although the advent of target therapy for lung cancer has brought about outstanding results, this benefit is confined to a subgroup of molecularly selected patients, whereas for most non-small cell lung cancer (NSCLC) patients, chemotherapy still represents the milestone of treatment.
- PMID 26898217
- Elucidation of novel budding yeast separase mutants.
- Shimizu Y1, Nagai M1, Yeasmin AM2, Koike N1, Talukdar MW2, Ushimaru T1,2.
- Bioscience, biotechnology, and biochemistry.Biosci Biotechnol Biochem.2016 Mar;80(3):473-8. doi: 10.1080/09168451.2015.1101337. Epub 2015 Nov 2.
- The mitotic separase cleaves Scc1 in cohesin to allow sister chromatids to separate from each other upon anaphase onset. Separase is also required for DNA damage repair. Here, we isolated and characterized 10 temperature-sensitive (ts) mutants of separase ESP1 in the budding yeast Saccharomyces cere
- PMID 26523765
Japanese Journal
- Fission yeast Scp3 potentially maintains microtubule orientation through bundling.
- Overexpression of DRG2 Increases G<sub>2</sub>/M Phase Cells and Decreases Sensitivity to Nocodazole-Induced Apoptosis
Related Links
- mitotic poison [mī′täd·ik ′pȯiz·ən] (cell and molecular biology) A compound that prevents or affects the completion of mitosis.
- Any chemical compound that kills dividing cells. Some mitotic poisons are spindle poisons (q.v.), and others block topoisomerases (q.v.). Poisoned cells are arrested at the spindle or DNA damage checkpoints, and they subsequently ...
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- 関
- mitoses、mitosis