微小変化群
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- 1. 軽症熱傷の治療treatment of minor thermal burns [show details]
…States alone, the majority are minor and can be managed on an outpatient basis without the need for burn specialist consultation . Initial treatment of isolated, minor thermal injuries consists mainly …
- 2. 乳児および小児における軽度頭部外傷：マネージメントminor head trauma in infants and children management [show details]
…that identifies almost all infants and children with ciTBI after minor head trauma without overuse of CT. Most infants and children with minor head trauma can be safely discharged home after careful evaluation …
- 3. 乳児や小児の軽微な頭部外傷：評価minor head trauma in infants and children evaluation [show details]
…Most head trauma in children is minor and not associated with brain injury or long-term sequelae. However, a small number of children who appear to be at low risk after minor head trauma may have a clinically …
- 4. 一過性脳虚血発作および軽度の虚血性脳卒中の初期評価およびマネージメントinitial evaluation and management of transient ischemic attack and minor ischemic stroke [show details]
…other contraindications The presence of persistent but minor, nondisabling neurologic deficits is the main factor that distinguishes minor ischemic stroke from a time-based TIA. However, both are associated …
- 5. 成人の単極性小うつ病：マネージメントunipolar minor depression in adults management [show details]
…depression ranges in severity from subsyndromal symptoms to the syndromes of minor depression and major depression . Unipolar minor depression is characterized by two to four depressive symptoms that are present …
English Journal
- Middle ear abnormalities at age 5 years in relation with early onset otitis media and number of episodes, in the Inuit population of Nunavik, Quebec, Canada.
- De Wals P, Lemeur JB, Ayukawa H, Proulx JF.
- International journal of circumpolar health. 2019 Dec;78(1)1599269.
- Otitis media (OM) and their sequelae are a major health issue in the Inuit population of Nunavik, Quebec. Hypotheses of the study were: (i) early onset OM leads to repeated OM; (ii) repeated OM episodes leads to middle ear abnormalities (MEA) at age 5 years, (iii) pneumococcal conjugate vaccines (P
- PMID 30924406
- Comparison between MassARRAY and pyrosequencing for CYP2C19 and ABCB1 gene variants of clopidogrel efficiency genotyping.
- Liu J, Xu Z, Li Y, Dai S, Liu J, Pan J, Jiang Y.
- Molecular membrane biology. 2019 Dec;35(1)1-8.
- Clopidogrel is one of the most frequently used drugs in patients to reduce cardiovascular events. Since patients with different genetic variations respond quite differently to clopidogrel therapy, the related genetic testing plays a vital role in its dosage and genetic testing related to clopidogrel
- PMID 30916611
- Bedside placement of peritoneal dialysis catheters - a single-center experience from Hungary.
- Pethő Á, Szabó RP, Tapolyai M, Rosivall L.
- Renal failure. 2019 Nov;41(1)434-438.
- Array
- PMID 31162993
Related Links
- AHRQ QI ICD-10-CM/PCS Specification v2018 Pediatric Quality Indicators Appendices www.qualityindicators.ahrq.gov Appendix G M3321 Polymyositis with respiratory involvement N060 Isolated proteinuria with minor glomerular ...
- specimens showed minor glomerular abnormalities in six patients, mesangial proliferative glomerulonephritis (GN) in 21, membranous nephropathy in seven, renal amyloidosis in seven, and tubulo-interstitial nephritis in two. Twelve ...
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★リンクテーブル★
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- 英
- minimal change disease
- 同
- 微少変化群、微小糸球体変化 minor glomerularabnormality、リポイドネフローゼ lipoid nephrosis
- 微小変化型ネフローゼ症候群 minimal change nephrotic syndrome, MCNS
- 関
- 一次性ネフローゼ症候群、原発性ネフローゼ症候群
概念
- 光学顕微鏡で糸球体に変化が認められないが電子顕微鏡で異常が認められる。
- 小児に多い。
- 小児のネフローゼ症候群の約80％を微小変化群がしめる。
- 成人のネフローゼ症候群の約20％を微小変化群がしめる。
疫学
- 小児に多い(2-6歳)。蛋白尿で発見(学校検尿で)
治療
予後
- 予後は良好→消失（治療する必要もなし） ← ？？？？
- 小児例
- 90%の症例でステロイドに反応して寛解。寛解例の2/3で再発し、いくらかはステロイド依存状態となる。25年後に5%の例で慢性腎不全となる。この群の殆どの人が巣状分節状糸球体硬化症をともなうネフローゼ症候群を呈している。(BPT.550)
- ステロイド療法に反応するが、治療への反応は小児例より遅く、また再発しやすい。(BPT.550)
病理
- 光学顕微鏡、蛍光で異常な変化（－）、電子顕微鏡で観察できる（＋）
[show details]
国試
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- 関
- a few、minority、small number、trace、trace amount