WordNet

PrepTutorEJDIC

Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells.

Poachanukoon O1, Koontongkaew S, Monthanapisut P, Pattanacharoenchai N.
Pharmacology.Pharmacology.2014;93(1-2):92-9. doi: 10.1159/000358366. Epub 2014 Feb 18.
BACKGROUND/AIMS: Macrolide antibiotics are effective drugs in chronic bronchiolitis and chronic rhinosinusitis with mucus hypersecretion. However, the mechanism of action is unclear. This study was designed to investigate the effect of azithromycin (AZM; 15-membered) and midecamycin acetate (MDM; 16
PMID 24556631

Quantitative determination of erythromycylamine in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study of dirithromycin.

Liu YQ1, Chen QY, Chen BM, Liu SG, Deng FL, Zhou P.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2008 Mar 15;864(1-2):1-8. doi: 10.1016/j.jchromb.2007.12.021. Epub 2008 Jan 4.
A sensitive, rapid liquid chromatographic-electrospray ionization mass spectrometric method for determination of erythromycylamine in human plasma was developed and validated. Erythromycylamine in plasma (0.2 mL) was extracted with ethyl acetate, the organic phase was transferred to another clear 1.
PMID 18296129

Modulatory effect of macrolide antibiotics on the Th1- and Th2-type cytokine production.

Morikawa K1, Zhang J, Nonaka M, Morikawa S.
International journal of antimicrobial agents.Int J Antimicrob Agents.2002 Jan;19(1):53-9.
The effect of the macrolide antibiotics, clarithromycin, midecamycin acetate and josamycin, on the generation of Th1- and Th2-type cytokines by mitogen-stimulated human T lymphocytes was compared with that of fosfomycin. The following results were obtained. These drugs demonstrated potent inhibitory
PMID 11814768