microdosing

出典: meddic

  • n.
microdose study

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/15 13:40:33」(JST)

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英文文献

  • Fluorescence guided surgery and tracer-dose, fact or fiction?
  • KleinJan GH1,2, Bunschoten A1, van den Berg NS1,3, Olmos RA1,2, Klop WM4, Horenblas S3, van der Poel HG3, Wester HJ5, van Leeuwen FW6,7,8.
  • European journal of nuclear medicine and molecular imaging.Eur J Nucl Med Mol Imaging.2016 Mar 28. [Epub ahead of print]
  • INTRODUCTION: Fluorescence guidance is an upcoming methodology to improve surgical accuracy. Challenging herein is the identification of the minimum dose at which the tracer can be detected with a clinical-grade fluorescence camera. Using a hybrid tracer such as indocyanine green (ICG)-99mTc-nanocol
  • PMID 27020580
  • CYP3A activity: towards dose adaptation to the individual.
  • Hohmann N1, Haefeli WE1, Mikus G1.
  • Expert opinion on drug metabolism & toxicology.Expert Opin Drug Metab Toxicol.2016 Mar 26:1-19. [Epub ahead of print]
  • INTRODUCTION: Co-medication, gene polymorphisms and co-morbidity are main causes for high variability in expression and function of the CYP3A isoenzymes. Pharmacokinetic variability is a major source of interindividual variability of drug effect and response of CYP3A substrates. While CYP3A genotypi
  • PMID 26950050
  • Microdosing and other Phase-0 Clinical Trials: Facilitating Translation in Drug Development.
  • Burt T1, Yoshida K2,3, Lappin G4, Vuong L5,6, John C2, de Wildt SN7, Sugiyama Y8, Rowland M9,10.
  • Clinical and translational science.Clin Transl Sci.2016 Feb 26. doi: 10.1111/cts.12390. [Epub ahead of print]
  • Increasing costs of drug development and ethical concerns about the risks of exposing humans and animals to novel chemical entities favor limited exposure clinical trials such as microdosing and other Phase-0 trials. An increasing body of research supports the validity of extrapolation from the limi
  • PMID 26918865

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MicrodosingMicrodosing (Phase 0) studiesMicrodosing Proves Superior to Animal Drug PRECLINICAL TESTS INFORMATION: MicrodosingPLP Microdosing equipment in human microdosing of development drugs


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リンク元マイクロドーズ臨床試験」「マイクロドージング」「microdose study

マイクロドーズ臨床試験」

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microdose studymicrodosing
マイクロドージング


マイクロドージング」

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microdosing
マイクロドーズ臨床試験

microdose study」

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microdosing




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