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  • Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.
  • Juvvadi PR1, Muñoz A2, Lamoth F3, Soderblom EJ4, Moseley MA4, Read ND2, Steinbach WJ5.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Aug;59(8):4946-55. doi: 10.1128/AAC.00263-15. Epub 2015 Jun 8.
  • The echinocandin antifungal drug caspofungin at high concentrations reverses the growth inhibition of Aspergillus fumigatus, a phenomenon known as the "paradoxical effect," which is not consistently observed with other echinocandins (micafungin and anidulafungin). Previous studies of A. fumigatus re
  • PMID 26055379
  • Altered Micafungin Pharmacokinetics in Intensive Care Unit Patients.
  • Lempers VJ1, Schouten JA2, Hunfeld NG3, Colbers A1, van Leeuwen HJ4, Burger DM1, Verweij PE5, Pickkers P6, Brüggemann RJ7.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Aug;59(8):4403-9. doi: 10.1128/AAC.00623-15. Epub 2015 May 11.
  • Micafungin is considered an important agent for the treatment of invasive fungal infections in the intensive care unit (ICU). Little is known on the pharmacokinetics of micafungin. We investigated micafungin pharmacokinetics (PK) in ICU patients and set out to explore the parameters that influence m
  • PMID 25963988
  • Isavuconazole, micafungin, and 8 comparator antifungal agents' susceptibility profiles for common and uncommon opportunistic fungi collected in 2013: temporal analysis of antifungal drug resistance using CLSI species-specific clinical breakpoints and proposed epidemiological cutoff values.
  • Pfaller MA1, Rhomberg PR2, Messer SA2, Jones RN2, Castanheira M2.
  • Diagnostic microbiology and infectious disease.Diagn Microbiol Infect Dis.2015 Aug;82(4):303-13. doi: 10.1016/j.diagmicrobio.2015.04.008. Epub 2015 Apr 29.
  • The in vitro activities of isavuconazole, micafungin, and 8 comparator antifungal agents were determined for 1613 clinical isolates of fungi (1320 isolates of Candida spp., 155 of Aspergillus spp., 103 of non-Candida yeasts, and 35 non-Aspergillus molds) collected during a global survey conducted in
  • PMID 25986029


  • Endotoxin does not alter the pharmacokinetics of micafungin, but it impairs biliary excretion of micafungin via multidrug resistance-associated protein 2 (ABCC2/Mrp2) in rats
  • NODA Takayuki,ABE Fumie,UEYAMA Jun,KATO Miki,KATOH Miki,NADAI Masayuki,SAITO Hiroko,HASEGAWA Takaaki
  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 17(2), 207-213, 2011-04-01
  • NAID 10028171423
  • 急速に進行し菌球様陰影を呈した肺Aspergillus niger症の1例
  • 齋藤 雅俊,四宮 祥平,北楯 祥子,高原 豊,山谷 淳代,小島 好司,藤本 由貴,及川 卓,中川 研,土原 一真,井口 晶晴,長内 和弘,栂 博久
  • 気管支学 : 日本気管支研究会雑誌 33(1), 33-37, 2011-01-25
  • 症例.63歳,男性.3カ月前より乾性咳嗽を自覚し近医受診,間質性肺炎の診断で2カ月前からプレドニゾロン30mg/日の内服を開始された.1カ月前から咳嗽の増悪と全身倦怠感があり当院紹介となった.受診時38℃台の発熱と低酸素血症を認め,両側上肺野に吸気終末cracklesを聴取した.採血では核の左方移動を伴うWBC上昇と炎症反応上昇を認め,アスペルギルス抗原が陽性であった.画像上は両側上葉に空洞形成と …
  • NAID 110008460780
  • FKS2遺伝子内変異による Micafungin 低感受性 Candida glabrata が検出された1例
  • 乾 佐知子,中村 竜也,田辺 公一,大野 秀明,小池 千裕,奥田 和之,中田 千代,藤本 弘子,大倉 ひろ枝,宮崎 義継,高橋 伯夫
  • 感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 85(1), 49-53, 2011-01-20
  • NAID 10028048310


Micafungin (trade name Mycamine) is an echinocandin antifungal drug developed by Astellas Pharma. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. Micafungin is administered intravenously.
最終データ更新日:2011-03-31. Micafungin [MCFG]. ミカファンギンナトリウム, キャンディン系. 1. 商品名. 先発品. ファンガード点滴用25mg/ファンガード点滴用 50mg/ファンガード点滴用75mg 【アステラス製薬】. 2. 日本における発売年. 2002( 平成14)年 ...


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