出典: meddic


Flagyl, Metro-IV

WordNet   license wordnet

「antiprotozoal medication (trade name Flagyl) used to treat trichomoniasis and giardiasis」

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/11/27 14:07:49」(JST)

wiki en

[Wiki en表示]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/07/19 17:50:00」(JST)

wiki en

[Wiki en表示]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/12/03 16:21:42」(JST)

wiki en

[Wiki en表示]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/12/14 04:22:42」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • Carbon paste electrode modified with duplex molecularly imprinted polymer hybrid film for metronidazole detection.
  • Xiao N1, Deng J2, Cheng J3, Ju S1, Zhao H1, Xie J1, Qian D1, He J1.
  • Biosensors & bioelectronics.Biosens Bioelectron.2016 Jul 15;81:54-60. doi: 10.1016/j.bios.2016.02.041. Epub 2016 Feb 17.
  • A novel electrochemical sensor based on duplex molecularly imprinted polymer (DMIP) hybrid film modified carbon paste electrode (CPE) has been developed for highly sensitive and selective determination of metronidazole (MNZ). A conductive poly(anilinomethyltriethoxysilane) film is firstly electrodep
  • PMID 26921552
  • Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology.
  • Lal N1, Jangir S1, Bala V2, Mandalapu D1, Sarswat A1, Kumar L1, Jain A3, Kumar L3, Kushwaha B3, Pandey AK4, Krishna S5, Rawat T1, Shukla PK4, Maikhuri JP3, Siddiqi MI5, Gupta G3, Sharma VL6.
  • European journal of medicinal chemistry.Eur J Med Chem.2016 Jun 10;115:275-90. doi: 10.1016/j.ejmech.2016.03.012. Epub 2016 Mar 9.
  • Trichomoniasis and candidiasis are amongst the most common morbidity-causing reproductive tract infections, generally treated by Metronidazole and Fluconazole respectively. Poor vaginal efficacy, drug-resistance and non-spermicidal nature limit their use as topical microbicidal contraceptives. Bis(d
  • PMID 27084496
  • Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids.
  • Negi B1, Kumar D1, Kumbukgolla W2, Jayaweera S2, Ponnan P1, Singh R3, Agarwal S3, Rawat DS4.
  • European journal of medicinal chemistry.Eur J Med Chem.2016 Jun 10;115:426-37. doi: 10.1016/j.ejmech.2016.03.041. Epub 2016 Mar 18.
  • MRSA causes 60-70% of Staphylococcus aureus infection in hospitals and it has developed resistance against the currently available drugs. Interestingly, a series of 35 metronidazole-triazole hybrids on screening against MRSA were found to be active. Compound 22 was found to be effective at 4 μg/mL
  • PMID 27046397


  • 4-2.がん皮膚浸潤に対する異臭菌同定とmetronidazoleの有効性の検討
  • 眞中 章弘,小林 剛,奥澤 直美,間島 竹彦,佐橋 幸子
  • The Kitakanto medical journal 62(3), 355-355, 2012-08-01
  • NAID 120004606925
  • Clostridium difficile Colitis and Neutropenic Fever Associated with Docetaxel Chemotherapy in a Patient with Advanced Extramammary Paget’s Disease
  • Nonomura Yumi,Otsuka Atsushi,Endo Yuichiro,Fujisawa Akihiro,Tanioka Miki,Kabashima Kenji,Miyachi Yoshiki
  • Case Reports in Dermatology 4(2), 177-180, 2012-08
  • … The patient showed complete resolution of her symptoms within 2 weeks with an oral metronidazole therapy. …
  • NAID 120004873859
  • 症例報告 女性に発症した感染経路不明のアメーバ性肝膿瘍の1例
  • 松村 篤,井村 健一郎,山岡 延樹 [他]
  • 京都府立医科大学雑誌 121(6), 331-336, 2012-06
  • NAID 40019369434


Metronidazole [MNZ,MTZ]. メトロニダゾール, 抗原虫剤. 1. 商品名 ... 用法・用量. トリコモナス症(腟トリコモナスによる感染症):通常,成人にはメトロニダゾールとして,1 クールとして,1回250mgを1日2回,10日間経口投与する。 胃潰瘍・十二指腸潰瘍 における ...


Order Metronidazole Online, Best Online Metronidazole Vaginal Cream MetronidazoleMetronidazole 250 mg (Per Tablet)Metronidazole for Dogs & Cats (Generic Metronidazole antiprotozoal tablets for All About Metronidazole For Dogs | Tex Dot

拡張検索metronidazole-induced encephalopathy



metronidazole, MTZ
フラジール Flagyl, Metro-IV、アスゾールランピオンパック(ランソプラゾールアモキシシリンメトロニダゾール)
  • first aid step1 2006 p.139,142,148,165,172,178,208,276,282



作用機序 PPC. 641, 647

  • メトロニダゾールの活性化には嫌気性生物の発酵に関与する酵素 pyruvate-derredocin oxidoreductase,PFORが必要
  • pyruvate-ferredoxin oxidoreductaseはferredoxinをreduced ferredoxinに変換するが、これに共役してメトロニダゾールがreduced metronidazole(活性型)に変換される。
  • 微生物の蛋白質、膜、DNAに傷害を与える


USMLE (first aid step1 2006 p.172)

H. pylori:bismuth + amoxicillin/tetracycline + metronidazole


  • disulfiram-like reaction with alcohol; headache,metallic taste (first aid step1 2006 p.172)




WordNet   license wordnet

「based on the meter as a standard of measurement; "the metric system"; "metrical equivalents"」

PrepTutorEJDIC   license prepejdic

「メートル法の / =metrical」

metronidazole-induced encephalopathy」

  [★] メトロニダゾール脳症