メチルチアゾールテトラゾリウム
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- MTT
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English Journal
- Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells.
- Yamazaki H1, Takagi S2, Hosoya K3, Okumura M3.
- Veterinary journal (London, England : 1997).Vet J.2015 Sep;205(3):375-80. doi: 10.1016/j.tvjl.2015.05.003. Epub 2015 May 8.
- Histiocytic sarcoma (HS) in dogs exhibits aggressive biological behaviors and currently few effective treatments are available. Survivin could serve as a potential therapeutic target in several cancers. Sepantronium bromide (YM155) is a potential novel survivin-targeting agent and in this study the
- PMID 26048444
- SiRNA knockdown of the DEK nuclear protein mRNA enhances apoptosis and chemosensitivity of canine transitional cell carcinoma cells.
- Yamazaki H1, Iwano T1, Otsuka S2, Kagawa Y3, Hoshino Y4, Hosoya K1, Okumura M1, Takagi S5.
- Veterinary journal (London, England : 1997).Vet J.2015 Apr;204(1):60-5. doi: 10.1016/j.tvjl.2015.02.009. Epub 2015 Feb 12.
- Transitional cell carcinoma (TCC) in dogs is an aggressive malignant neoplasm, originating in the epithelium of the urinary bladder. The DEK nuclear protein is overexpressed in several types of human bladder cancer, where it is involved in chromatin reconstruction, gene transcription and apoptosis.
- PMID 25773167
- Chojalactones A-C, cytotoxic butanolides isolated from Streptomyces sp. cultivated with mycolic acid containing bacterium.
- Hoshino S1, Wakimoto T1, Onaka H2, Abe I1.
- Organic letters.Org Lett.2015 Mar 20;17(6):1501-4. doi: 10.1021/acs.orglett.5b00385. Epub 2015 Mar 5.
- The soil-derived bacterium, Streptomyces sp. CJ-5, was cocultured with the mycolic acid-containing bacterium Tsukamurella pulmonis TP-B0596. The combined culture method significantly enhanced the production of the secondary metabolites in Streptomyces sp. CJ-5, leading to the isolation of three nove
- PMID 25742189
Japanese Journal
- Inhibition of Survivin Influences the Biological Activities of Canine Histiocytic Sarcoma Cell Lines
- Yamazaki Hiroki,Takagi Satoshi,Hoshino Yuki,Hosoya Kenji,Okumura Masahiro
- PLoS One 8(11), 2013-11-15
- … We comparatively analyzed the expression of 6 selected anti-apoptotic genes, including survivin, in specimens from 30 dogs with histiocytic sarcoma and performed annexin V staining to evaluate apoptosis, methylthiazole tetrazolium assays to assess cell viability and chemosensitivity, and latex bead assays to measure changes in phagocytic activities in 4 CHS cell lines and normal canine fibroblasts transfected with survivin siRNA. …
- NAID 120005372282
Related Links
- MTT: Methylthiazole Tetrazolium, メチルチアゾールテトラゾリウム mRNA: messenger Ribonucleic Acid PBS: Phosphate-buffered Saline, リン酸緩衝生理食塩水 ROC: Receiver Operating Characteristic, 受信者動作特性 RT-PCR 3 ...
- 時間での生存細胞の存在をmethylthiazole tetrazolium （MTT）法に基づいて検出した。 4．皮下移植腫瘍モデルを用いたin vivo抗腫瘍効果の評価 継代培養したHuH-7細胞を回収し、無血清DMEMに懸濁した。50 %マトリゲル（Becton 6 ...
- MTT : methylthiazole tetrazolium NMDG : N-methyl-D-glucamin NTCP : sodium taurocholate cotransporting polypeptide PBS : phosphate buffered saline 5 PEG : polyethylene glycol pgRNA : pregenomic RNA RaPID : random 6 ...
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- methylthiazole tetrazolium、MTT