methylmalonyl pathway

出典: meddic


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  • Engineering of Ralstonia eutropha for the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) from glucose.
  • Zhang YZ1, Liu GM2, Weng WQ2, Ding JY3, Liu SJ4.
  • Journal of biotechnology.J Biotechnol.2014 Dec 23;195C:82-88. doi: 10.1016/j.jbiotec.2014.12.014. [Epub ahead of print]
  • Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) with Ralstonia eutropha relies on the addition of propionate during fermentation, and propionate consumption is one of the major factors affecting the cost of PHBV production. In this study, 7 strains were obtained by genetic manipula
  • PMID 25541463
  • MicroRNA-9 regulates neural apoptosis in methylmalonic acidemia via targeting BCL2L11.
  • Li Y1, Peng T1, Li L2, Wang X1, Duan R1, Gao H1, Guan W1, Lu J1, Teng J1, Jia Y3.
  • International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience.Int J Dev Neurosci.2014 Aug;36:19-24. doi: 10.1016/j.ijdevneu.2014.04.005. Epub 2014 May 2.
  • Methylmalonic acidemia (MMA) is an autosomal-recessive inborn metabolic disorder that results from a deficiency in methylmalonyl-coenzyme A mutase or its cofactor, adenosylcobalamin. Currently, neurological manifestations in MMA are thought to be associated with neural apoptosis. BCL2L11, which is a
  • PMID 24798023
  • Phylogenetic distribution of three pathways for propionate production within the human gut microbiota.
  • Reichardt N1, Duncan SH2, Young P2, Belenguer A2, McWilliam Leitch C2, Scott KP2, Flint HJ2, Louis P2.
  • The ISME journal.ISME J.2014 Jun;8(6):1323-35. doi: 10.1038/ismej.2014.14. Epub 2014 Feb 20.
  • Propionate is produced in the human large intestine by microbial fermentation and may help maintain human health. We have examined the distribution of three different pathways used by bacteria for propionate formation using genomic and metagenomic analysis of the human gut microbiota and by designin
  • PMID 24553467


  • 12 マクロラクタム配糖体インセドニンの生合成におけるアミノ酸スターター部位構築機構(口頭発表の部)
  • 天然有機化合物討論会講演要旨集 (54), 67-72, 2012-09-01
  • NAID 110010013805
  • ビタミンB_<12>欠乏ラットの脳におけるOtx2遺伝子発現量の変動
  • Aerobic Culture of Propionibacterium freudenreichii ET-3 Can Increase Production Ratio of 1,4-Dihydroxy-2-Naphthoic Acid to Menaquinone (BIOCHEMICAL ENGINEERING)
  • Journal of bioscience and bioengineering 101(6), 464-470, 2006-06-25
  • NAID 110004758118


Methylmalonyl Coenzyme A mutase, also known as MCM is an enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA and it is involved in key metabolic pathways. It requires a vitamin B12-derived prosthetic group, ...
A collection of model organism databases of metabolic pathways, including reactions, enzymes, genes and substrate compounds.


Propionyl-CoA metabolism in plants:Methylmalonyl-CoA mutase deficiency The diagram below summarizes this pathway in the methylmalonyl pathway propionyl Methylmalonyl Coa Mutase Pathways for Methylmalonic Acid The essential amino




methylmalonyl pathway




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