metabotropic glutamate receptor

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/02 01:10:58」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/10/14 12:39:42」(JST)

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  • The two faces of the pharmacological interaction of mGlu2 and 5-HT2A - Relevance of receptor heterocomplexes and interaction through functional brain pathways.
  • Delille HK, Mezler M, Marek GJ.SourceAbbott Diagnostics Division, Max-Planck-Ring 2, 65205 Wiesbaden, Germany.
  • Neuropharmacology.Neuropharmacology.2013 Jul;70:296-305. doi: 10.1016/j.neuropharm.2013.02.005. Epub 2013 Mar 4.
  • Important functional interactions between the metabotropic glutamate 2 (mGlu2) and 5-hydroxytryptamine2A (5-HT2A) neurotransmitter receptors have been established based on electrophysiological, biochemical and behavioral evidence. Over the last several years, dimerization between 5-HT2A and mGlu2 re
  • PMID 23466331
  • Effect of an mGlu2/3 receptor antagonist on depressive behavior induced by withdrawal from chronic treatment with methamphetamine.
  • Iijima M, Koike H, Chaki S.SourceDiscovery Pharmacology І, Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan.
  • Behavioural brain research.Behav Brain Res.2013 Jun 1;246:24-8. doi: 10.1016/j.bbr.2013.02.039. Epub 2013 Mar 5.
  • Withdrawal from chronic treatment with a psychostimulant precipitates behavioral and physiological conditions similar to the symptoms of major depressive disorder (MDD). Accumulated studies have indicated that withdrawal from a psychostimulant in rodents elicits depressive phenotypes including despa
  • PMID 23473878
  • Expression of CRFR1 and Glu5R mRNA in different brain areas following repeated testing in mice that differ in habituation behaviour.
  • Salomons AR, Arndt SS, Lavrijsen M, Kirchhoff S, Ohl F.SourceDepartment of Animals in Science and Society, Division of Animal Welfare and Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands; Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands. Electronic address:
  • Behavioural brain research.Behav Brain Res.2013 Jun 1;246:1-9. doi: 10.1016/j.bbr.2013.02.023. Epub 2013 Feb 28.
  • Our recent studies revealed a profound impairment to habituate in 129P3 mice compared to BALB/c mice after repeated exposure to an initially novel environment. This was accompanied by strain-specific c-Fos expression in the prelimbic cortex, a brain area related to emotional and cognitive processing
  • PMID 23458743


  • 受賞講演総説 mGluR機能の可視化と探索 : 代謝型グルタミン酸受容体シグナリングの可視化解析
  • 大久保 洋平
  • 日本薬理学雑誌 = Folia pharmacologica Japonica : くすりとからだ : ファーマコロジカ 144(2), 76-80, 2014-08
  • NAID 40020174062
  • Synthesis and Biological Evaluation of 2-Substituted Quinoline 6-Carboxamides as Potential mGluR1 Antagonists for the Treatment of Neuropathic Pain
  • Kim Younghee,Son Jiwon,Kim Juhyeon [他]
  • Chemical and pharmaceutical bulletin 62(6), 508-518, 2014-06
  • NAID 40020073439
  • Regulation and functional roles of rebound potentiation at cerebellar stellate cell—Purkinje cell synapses
  • Hirano Tomoo,Kawaguchi Shin-ya
  • Frontiers in Cellular Neuroscience 8, 2014-02-18
  • … The increase in intracellular Ca[2+] concentration caused by depolarization induces RP through enhancement of GABAA receptor (GABAAR) responsiveness. … Whether RP is induced or not is determined by the balance between phosphorylation and de-phosphorylation activities regulated by intracellular Ca[2+] and by metabotropic GABA and glutamate receptors. …
  • NAID 120005385884


 metabotropic glutamate receptors (Table 1, Metabotropic Glutamate; Glutamate , Metabotropic Glutamate; Glutamate Metabotropic Glutamate ReceptorsGPCR, the metabotropic glutamate receptor Glutamate Receptor Glutamate receptor

関連記事receptor」「glutamate」「metabotropic」「glutamate receptor



metabotropic glutamate receptormGluR
Metabotropic glutamate receptors



metabotropic glutamate receptormGluR



metabotropic glutamate receptor



metabotropic glutamate receptor
Metabotropic glutamate receptors


  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」




WordNet   license wordnet

「a salt or ester of glutamic acid」



  • 代謝調節型の、代謝型の、向代謝性の

glutamate receptor」

  [★] グルタミン酸受容体