metabotropic glutamate receptor

出典: meddic


Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/02 01:10:58」(JST)

wiki en

[Wiki en表示]

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.


  • The two faces of the pharmacological interaction of mGlu2 and 5-HT2A - Relevance of receptor heterocomplexes and interaction through functional brain pathways.
  • Delille HK, Mezler M, Marek GJ.SourceAbbott Diagnostics Division, Max-Planck-Ring 2, 65205 Wiesbaden, Germany.
  • Neuropharmacology.Neuropharmacology.2013 Jul;70:296-305. doi: 10.1016/j.neuropharm.2013.02.005. Epub 2013 Mar 4.
  • Important functional interactions between the metabotropic glutamate 2 (mGlu2) and 5-hydroxytryptamine2A (5-HT2A) neurotransmitter receptors have been established based on electrophysiological, biochemical and behavioral evidence. Over the last several years, dimerization between 5-HT2A and mGlu2 re
  • PMID 23466331
  • Effect of an mGlu2/3 receptor antagonist on depressive behavior induced by withdrawal from chronic treatment with methamphetamine.
  • Iijima M, Koike H, Chaki S.SourceDiscovery Pharmacology І, Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama, Saitama 331-9530, Japan.
  • Behavioural brain research.Behav Brain Res.2013 Jun 1;246:24-8. doi: 10.1016/j.bbr.2013.02.039. Epub 2013 Mar 5.
  • Withdrawal from chronic treatment with a psychostimulant precipitates behavioral and physiological conditions similar to the symptoms of major depressive disorder (MDD). Accumulated studies have indicated that withdrawal from a psychostimulant in rodents elicits depressive phenotypes including despa
  • PMID 23473878
  • Expression of CRFR1 and Glu5R mRNA in different brain areas following repeated testing in mice that differ in habituation behaviour.
  • Salomons AR, Arndt SS, Lavrijsen M, Kirchhoff S, Ohl F.SourceDepartment of Animals in Science and Society, Division of Animal Welfare and Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands; Rudolf Magnus Institute of Neuroscience, Utrecht, The Netherlands. Electronic address:
  • Behavioural brain research.Behav Brain Res.2013 Jun 1;246:1-9. doi: 10.1016/j.bbr.2013.02.023. Epub 2013 Feb 28.
  • Our recent studies revealed a profound impairment to habituate in 129P3 mice compared to BALB/c mice after repeated exposure to an initially novel environment. This was accompanied by strain-specific c-Fos expression in the prelimbic cortex, a brain area related to emotional and cognitive processing
  • PMID 23458743


  • 受賞講演総説 mGluR機能の可視化と探索 : 代謝型グルタミン酸受容体シグナリングの可視化解析
  • 大久保 洋平
  • 日本薬理学雑誌 = Folia pharmacologica Japonica : くすりとからだ : ファーマコロジカ 144(2), 76-80, 2014-08
  • NAID 40020174062
  • Synthesis and Biological Evaluation of 2-Substituted Quinoline 6-Carboxamides as Potential mGluR1 Antagonists for the Treatment of Neuropathic Pain
  • Kim Younghee,Son Jiwon,Kim Juhyeon [他]
  • Chemical and pharmaceutical bulletin 62(6), 508-518, 2014-06
  • NAID 40020073439
  • Regulation and functional roles of rebound potentiation at cerebellar stellate cell—Purkinje cell synapses
  • Hirano Tomoo,Kawaguchi Shin-ya
  • Frontiers in Cellular Neuroscience 8, 2014-02-18
  • … The increase in intracellular Ca[2+] concentration caused by depolarization induces RP through enhancement of GABAA receptor (GABAAR) responsiveness. … Whether RP is induced or not is determined by the balance between phosphorylation and de-phosphorylation activities regulated by intracellular Ca[2+] and by metabotropic GABA and glutamate receptors. …
  • NAID 120005385884




関連記事receptor」「glutamate」「metabotropic」「glutamate receptor



metabotropic glutamate receptormGluR
Metabotropic glutamate receptors



metabotropic glutamate receptormGluR



metabotropic glutamate receptor



metabotropic glutamate receptor
Metabotropic glutamate receptors


  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」




WordNet   license wordnet

「a salt or ester of glutamic acid」



  • 代謝調節型の、代謝型の、向代謝性の

glutamate receptor」

  [★] グルタミン酸受容体