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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/30 21:42:51」(JST)
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In neurobiology, a mesaxon is a pair of parallel plasma membranes of a Schwann cell, marking the point of edge-to-edge contact by the Schwann cell encircling the axon. A single Schwann cell of the peripheral nervous system will wrap around and support only one individual axon (then myelinated; ratio of 1:1), while the oligodendrocytes found in the central nervous system can wrap around and support 5-8 axons. Thin unmyelinated axons are often bundled, with several unmyelinated axons to a single mesaxon (and several such groups to a single Schwann cell).
The outer mesaxon (Terminologia histologica: Mesaxon externum) is the connection of the outer cell membrane to the compact myelin sheath. The inner mesaxon (Terminologia histologica: Mesaxon internum) is the connection between the myelin sheath and the inner part of the cell membrane of the Schwann cell which is directly opposite the axolemma, i.e. the cell membrane of the nerve fibre ensheathed by the Schwann cell.
English Journal
- KV1 channels identified in rodent myelinated axons, linked to Cx29 in innermost myelin: Support for electrically-active myelin in mammalian saltatory conduction.
- Rash JE1, Vanderpool KG2, Yasumura T2, Hickman J2, Beatty JT2, Nagy JI3.
- Journal of neurophysiology.J Neurophysiol.2016 Jan 13:jn.01077.2015. doi: 10.1152/jn.01077.2015. [Epub ahead of print]
- Saltatory conduction in mammalian myelinated axons was thought to be well understood before recent discoveries revealed unexpected subcellular distributions and molecular identities of the K+-conductance pathways that provide for rapid axonal repolarization. Here, we visualize, identify, localize, q
- PMID 26763782
- Altered trafficking of abnormal prion protein in atypical scrapie: Prion protein accumulation in oligodendroglial inner mesaxons.
- Jeffrey M1, González L1, Simmons MM2, Hunter N3, Martin S1, McGovern G1.
- Neuropathology and applied neurobiology.Neuropathol Appl Neurobiol.2016 Jan 10. doi: 10.1111/nan.12302. [Epub ahead of print]
- AIMS: Prion diseases exist in classical and atypical disease forms. Both forms are characterised by disease-associated accumulation of a host membrane sialoglycoprotein known as prion protein (PrPd ). In classical forms of prion diseases, PrPd can accumulate in the extracellular space as fibrillar a
- PMID 26750308
Japanese Journal
- Numbers of Olfactory Receptor Cells and Fine Structure of Olfactory Nerves in Various Birds
- Matsuzaki Osamu
- Zoological science 12(1), 117-123, 1995-02-15
- … Each small bundle was separated into several divisions by mesaxon which originated from Schwann cells. … In the anterior part of the nerve, the number of axons surrounded by mesaxon ranged between one and several dozen. …
- NAID 110003323280
- Number of Olfactory Receptor Cells and Fine Structure of Olfactory Nerve Fibers in the Pigeon, Columba livia
- Matsuzaki Osamu,Shibuya Tatsuaki,Hatanaka Tsuneo
- 動物学雑誌 91(3), 221-229, 1982-09-25
- … A small bundle was separated into several divisions by the mesaxon which is a part of a Schwann cell. … In the anterior portion of the nerve, the number of axons surrounded by the mesaxon was several to several dozens. …
- NAID 110003366214
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- Mesaxon definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! Added to Favorites Dictionary Thesaurus Word Dynamo Quotes Reference Translator Spanish Log In n. ...
- mesaxon /mes·ax·on/ (mes-ak´son) a pair of parallel membranes marking the line of edge-to-edge contact of Schwann cells encircling an axon. mes·ax·on (mĕz-ăk′sŏn′) n. The plasma membrane of the neurolemma that surrounds a ...
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