メサンギウム増殖性糸球体腎炎
WordNet
- nephritis marked by inflammation of the glomeruli of the kidney; characterized by decreased production of urine and by the presence of blood and protein in the urine and by edema
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/11/06 12:53:57」(JST)
[Wiki en表示]
| Mesangial proliferative glomerulonephritis |
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| Renal corpuscle. Intraglomerular mesangium is #5a. |
| Classification and external resources |
| Specialty |
urology |
| ICD-10 |
N00.3-N08.3 |
| DiseasesDB |
31877 |
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[edit on Wikidata]
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Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the mesangium.[1] There is some evidence that interleukin-10 may inhibit it in an animal model.[2] It is classified as type II lupus nephritis by the World Health Organization (WHO).
Contents
- 1 Mechanism
- 2 Diagnosis
- 3 Treatment
- 4 References
Mechanism
Mesangial cells in the renal glomerulus use endocytosis to take up and degrade circulating immunoglobulin. This normal process stimulates mesangial cell proliferation and matrix deposition. Therefore, during times of elevated circulating immunoglobulin (i.e. lupus and IgA nephropathy) one would expect to see an increased number of mesangial cells and matrix in the glomerulus. This is characteristic of nephritic syndromes.
Diagnosis
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Treatment
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References
- ^ "Definition: mesangial proliferative glomerulonephritis from Online Medical Dictionary".
- ^ Kitching AR, Katerelos M, Mudge SJ, Tipping PG, Power DA, Holdsworth SR (April 2002). "Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis". Clin. Exp. Immunol. 128 (1): 36–43. PMC 1906377 . PMID 11982588. doi:10.1046/j.1365-2249.2002.01793.x.
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Lupus nephritis
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- Class I (Minimal mesangial glomerulonephritis)
- Class II (Mesangial proliferative lupus nephritis)
- Class III (Focal proliferative nephritis)
- Class IV (Diffuse proliferative nephritis)
- Class V (Membranous nephritis)
- Class VI (Glomerulosclerosis)
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Diseases of the urinary system (N00–N39, 580–599)
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| Kidney disease |
| Glomerules |
Primarily
nephrotic |
| Non-proliferative |
- Minimal change
- Focal segmental
- Membranous
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| Proliferative |
- Mesangial proliferative
- Endocapillary proliferative
- Membranoproliferative/mesangiocapillary
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| By condition |
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Primarily
nephritic,
RPG |
| Type I RPG/Type II hypersensitivity |
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| Type II RPG/Type III hypersensitivity |
- Post-streptococcal
- Lupus
- IgA/Berger's
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| Type III RPG/Pauci-immune |
- Granulomatosis with polyangiitis
- Microscopic polyangiitis
- Eosinophilic granulomatosis with polyangiitis
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| General |
- glomerulonephritis
- glomerulonephrosis
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| Tubules |
- Renal tubular acidosis
- Acute tubular necrosis
- Genetic
- Fanconi syndrome
- Bartter syndrome
- Gitelman syndrome
- Liddle's syndrome
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| Interstitium |
- Interstitial nephritis
- Pyelonephritis
- Balkan endemic nephropathy
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| General |
| General syndromes |
- Nephritis
- Nephrosis
- Renal failure
- Acute renal failure
- Chronic kidney disease
- Uremic pericarditis
- Uremia
- Diabetes insipidus
- Renal papilla
- Major calyx/pelvis
- Hydronephrosis
- Pyonephrosis
- Reflux nephropathy
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| Vascular |
- Renal artery stenosis
- Renal ischemia
- Hypertensive nephropathy
- Renovascular hypertension
- Renal cortical necrosis
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| Other |
- Analgesic nephropathy
- Renal osteodystrophy
- Nephroptosis
- Abderhalden–Kaufmann–Lignac syndrome
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| Urinary tract |
| Ureter |
- Ureteritis
- Ureterocele
- Megaureter
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| Bladder |
- Cystitis
- Interstitial cystitis
- Hunner's ulcer
- Trigonitis
- Hemorrhagic cystitis
- Neurogenic bladder dysfunction
- Bladder sphincter dyssynergia
- Vesicointestinal fistula
- Vesicoureteral reflux
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| Urethra |
- Urethritis
- Non-gonococcal urethritis
- Urethral syndrome
- Urethral stricture/Meatal stenosis
- Urethral caruncle
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| Any/all |
- Obstructive uropathy
- Urinary tract infection
- Retroperitoneal fibrosis
- Urolithiasis
- Bladder stone
- Kidney stone
- Renal colic
- Malakoplakia
- Urinary incontinence
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UpToDate Contents
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English Journal
- Afadin is localized at cell-cell contact sites in mesangial cells and regulates migratory polarity.
- Tsurumi H1, Kurihara H2, Miura K1, Tanego A1, Ohta Y3, Igarashi T4, Oka A1, Horita S5, Hattori M5, Harita Y1.
- Laboratory investigation; a journal of technical methods and pathology.Lab Invest.2016 Jan;96(1):49-59. doi: 10.1038/labinvest.2015.133. Epub 2015 Nov 16.
- In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, which is the pathological characteristic of mesangial
- PMID 26568295
- Primary Cutaneous Nocardiosis in a Patient With Nephrotic Syndrome: A Case Report and Review of the Literature.
- Chen B1, Tang J, Lu Z, Wang N, Gao X, Wang F.
- Medicine.Medicine (Baltimore).2016 Jan;95(3):e2490. doi: 10.1097/MD.0000000000002490.
- Nocardia infection is not common in clinical practice and most cases occur as an opportunistic infection in immunocompromised patients.We report a case of primary cutaneous nocardiosis characterized by multiple subcutaneous abscesses due to Nocardia brasiliensis in a patient with nephrotic syndrome
- PMID 26817885
- Twenty-eight-year review of childhood renal diseases from renal biopsy data: A single centre in China.
- Jiang M1, Xiao Z2, Rong L1, Xu Y1, Chen L1, Mo Y1, Sun L1, Sun W3, Jiang X1.
- Nephrology (Carlton, Vic.).Nephrology (Carlton).2015 Dec 23. doi: 10.1111/nep.12702. [Epub ahead of print]
- AIMS: This study aimed to investigate the clinicopathologic characteristics of biopsy-proven childhood renal diseases and to compare the trends and changes during 2 different time intervals between 1984 and 2011 at the 1st affiliated hospital of Sun Yat-sen University in China.METHODS: We retrospect
- PMID 26698187
Japanese Journal
- Canine IgA nephropathy: a case report
- Canine IgA nephropathy: a case report
Related Links
- 1. Lab Invest. 1978 Jul;39(1):21-9. Mesangial proliferative glomerulonephritis. Bhasin HK, Abuelo JG, Nayak R, Esparza AR. Eleven cases of mesangial proliferative glomerulonephritis whose kidney biopsies were studied with light ...
- Mesangial proliferative glomerulonephritis information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. ... Mesangial proliferative glomerulonephritis ...
★リンクテーブル★
[★]
- 英
- mesangioproliferative glomerulonephritis, mesangial proliferative glomerulonephritis
- 同
- メサンギウム性糸球体腎炎 mesangiopathic glomerulonephritis
- 関
- メサンギウム
- 病理的な疾患概念
- IgA腎症がほとんどで、非IgA腎症/炎としてIgM腎症などがある。(YN.E-46)
[★]
- 関
- multiplicative、productive、productively、proliferating
[★]
- 関
- glomerular mesangium、mesangium
[★]
糸球体腎炎 GN