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Intrathecal liposomal cytarabine and leptomeningeal medulloblastoma relapse: a valuable therapeutic option.

Mastronuzzi A, Del Bufalo F, Iacono A, Secco DE, Serra A, Colafati GS, DE Ioris MA, Corsetti T.SourceDivision of Hematology/Oncology and Stem Cell Transplantation, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio, 4-00165, Rome, Italy. angela.mastronuzzi@opbg.net.
Anticancer research.Anticancer Res.2013 Aug;33(8):3515-8.
BACKGROUND: Relapsed medulloblastoma (MB) is a highly lethal disease, requiring for new effective treatment strategies. Intrathecal (IT) therapy both for de novo or relapsed brain tumors with meningeal metastasis is rarely used in first line and relapse protocols.PATIENTS AND METHODS: We report on t
PMID 23898128

147 Gamma Knife Treatment Results for Multiple Brain Metastases: A Multi-Institutional Prospective Study in Japan (Abbreviation; JLGK0901, UMIN ID; 00001812).

Yamamoto M.AbstractINTRODUCTION: This study was designed to examine whether gamma knife radiosurgery (GKRS) alone for patients with 5-10 brain metastases (BMs) is not inferior to that for patients with 2-4 BMs in terms of overall survival and other clinical results.
Neurosurgery.Neurosurgery.2013 Aug;60 Suppl 1:168-9. doi: 10.1227/01.neu.0000432738.94699.2b.
INTRODUCTION: This study was designed to examine whether gamma knife radiosurgery (GKRS) alone for patients with 5-10 brain metastases (BMs) is not inferior to that for patients with 2-4 BMs in terms of overall survival and other clinical results.METHODS: This was a prospective observational study o
PMID 23839414

Marginal zone B-cell lymphoma involving a longstanding fibrous meningioma: an initial manifestation of systemic disease.

Martin SE, Khalidi HS, Hattab EM.SourceDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202.
Human pathology.Hum Pathol.2013 Jul 11. pii: S0046-8177(13)00190-1. doi: 10.1016/j.humpath.2013.04.016. [Epub ahead of print]
The combined presence of meningioma and lymphoma involving the dura is exceptionally rare. A 62-year-old woman, radiologically diagnosed with meningioma 14 years prior but never treated, presented with headaches and visual symptoms. Magnetic resonance imaging demonstrated significant growth of the m
PMID 23850496

久保秀文,中須賀千代,多田耕輔,宮原誠,長谷川博康,原田有彦
山口医学 63(1), 25-30, 2014-02-01
… 6ヵ月後に突然の頭痛に続いて視力低下を来したため再入院となった.造影MRI検査と髄液細胞診から乳癌による髄膜癌腫症と診断した.MRIでは両側視神経に限局した転移も疑われた.急速に全身状態が悪化し入院後わずか7日目に死亡した.乳癌髄膜播種の予後は極めて不良で集学的治療を行っても6ヵ月以内にほとんどが死亡し予後の改善が得られていないのが現状である.Meningeal dissemination from breast cancer is reportedly rare in …
NAID 120005435143

小原健太,大重英行,岩田亮一,吉村晋一,淺井昭雄
Neuro-Oncologyの進歩 21(2), 44-47, 2014
… The mass was surgically resected.Histologically, the mass comprised meningeal elements and fibrous tissue and did not include glial tissue. …
NAID 130004690735

河本圭司
Neuro-Oncologyの進歩 20(1), 40-45, 2014
… system is not clear, but which tumors are accepted as pathological entities showing many blood vessels among the tumor cells.Vascular tumors are listed as hemangioma,hemangioblastoma, hemangiopericytoma, hemangioendothelioma, angiomatous meningioma, atypical meningioma, anaplastic meningioma, which tumors are made a different diagnosis on MRI, light microscopy, and electron microscopy.The correct diagnosis among the meningeal tumors is necessary at pre and post operative stage for neurosurgeons, because of the good …
NAID 130004648354