megakaryopoiesis

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megakaryocytopoiesis

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英文文献

  • Impact of preeclampsia on megakaryocytopoesis and platelet homeostasis of preterm infants.
  • Yang J1, Zhang H, Niu J, Mu X, Zhang X, Liu Y, Wang J, Chen Y.
  • Platelets.Platelets.2015 Jun 17:1-5. [Epub ahead of print]
  • The aim of this article is to investigate the megakaryopoyesis and thrombopoiesis in preterm infants born to mothers with preeclampsia and the potential effects mediated by soluble fms-like tyrosine kinase 1 (sFlt1) and thrombopoietin (TPO). A perspective case-control study was performed on 26 cord
  • PMID 26083681
  • Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells.
  • Han SH, Kim J, Her Y, Seong I, Park S, Bhattara D, Jin G, Lee K, Chung G, Hwang S, Bae YS, Kim J1.
  • BMB reports.BMB Rep.2015 Jun 16. pii: 3239. [Epub ahead of print]
  • We report that Pytosphingosine, a sphingolipid found in many organisms and implicated in cellular signaling, promotes megakaryocytic differentiation of myeloid leukemia cells. Specifically, Pytosphingosine induced several hallmark changes associated with megakaryopoiesis from K562 and HEL cells incl
  • PMID 26077028

和文文献

  • CLEC-2による生体応答制御 (特集 C型レクチン受容体による生体応答制御)
  • 臨床免疫・アレルギー科 = Clinical immunology & allergology 66(2), 122-128, 2016-08
  • NAID 40020941233
  • GATA-dependent regulation of TPO-induced <i>c-mpl</i> Gene Expression during Megakaryopoiesis
  • Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling.

関連リンク

TPO signaling in megakaryopoiesis Multiple growth factors support megakaryopoesis, the most important of which is thrombopoietin (TPO). TPO belongs to the four-helix bundle family of cytokines, which includes erythropoietin, G ...
megakaryopoiesis megakaryocytopoiesis. ... However, according to more recent studies, these autoantibodies, directed against glycoproteins of the integrin family, also prevent formation of new platelets via inhibited megakaryopoiesis or destruction of megakaryocytes within the bone marrow.

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