Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/19 18:50:45」(JST)

Mazaticol (Pentona) is an anticholinergic used as an antiparkinsonian agent in Japan.

References

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

Population pharmacokinetics of haloperidol using routine clinical pharmacokinetic data in Japanese patients.

Yukawa E, Hokazono T, Yukawa M, Ichimaru R, Maki T, Matsunaga K, Ohdo S, Anai M, Higuchi S, Goto Y.SourceLaboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Higashi-Ku, Fukuoka, Japan. yukawa@shunsan.phar.kyushu-u.ac.jp
Clinical pharmacokinetics.Clin Pharmacokinet.2002;41(2):153-9.
OBJECTIVE: To clarify the observed variability of haloperidol disposition in patients with psychiatric disorders.DESIGN: Retrospective population pharmacokinetic study.PARTICIPANTS: 218 Japanese patients aged 16 to 82 years who provided 391 serum haloperidol concentrations.METHODS: Routine clinical
PMID 11888334

[A computer-assisted EEG study on psychotropic properties of antiparkinsonian drugs].

Suitsu N.SourceDepartment of Neuropsychiatry, Kansai Medical University.
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.Seishin Shinkeigaku Zasshi.1992;94(3):238-62.
For the purpose of determining psychotropic properties of antiparkinsonian substances, the author has carried out a quantitative analytic study on EEG changes induced by six marketed antiparkinsonian drugs in young normal volunteers. The drugs were six antiparkinsonian agents, l-dopa (LDP) 100 mg, t
PMID 1589555

薬物性と器質性パ-キンソニズムに対するMazaticol hydrochloride(ペントナ)ならびにAmantadine hydrochlorideの治療効果の比較--Cross over法による検討

Mazaticol
Systematic (IUPAC) name
	[(1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(di-2-thienyl)acetate
Clinical data
Routes of; administration	Oral
Legal status	Uncontrolled;
Identifiers
CAS Number	42024-98-6
ATC code	N04AA10 (WHO)
PubChem	CID 68667
ChemSpider	61921
UNII	I6X824OGWZ
Chemical data
Formula	C21H27NO3S2
Molar mass	405.576 g/mol
	SMILES CC1(CC[C@@H]2C[C@H](C[C@H]1N2C)OC(=O)C(c3cccs3)(c4cccs4)O)C ;
	InChI InChI=1S/C21H27NO3S2/c1-20(2)9-8-14-12-15(13-16(20)22(14)3)25-19(23)21(24,17-6-4-10-26-17)18-7-5-11-27-18/h4-7,10-11,14-16,24H,8-9,12-13H2,1-3H3/t14-,15-,16-/m1/s1 ; Key:AMHPTVWBZSYFSS-BZUAXINKSA-N ;
(verify)

Systematic (IUPAC) name

[(1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(di-2-thienyl)acetate
Clinical data
Routes of administration	Oral
Legal status	Uncontrolled
Identifiers
CAS Number	42024-98-6
ATC code	N04AA10 (WHO)
PubChem	CID 68667
ChemSpider	61921
UNII	I6X824OGWZ^Y
Chemical data
Formula	C₂₁H₂₇NO₃S₂
Molar mass	405.576 g/mol
SMILES CC1(CC[C@@H]2C[C@H](C[C@H]1N2C)OC(=O)C(c3cccs3)(c4cccs4)O)C
InChI InChI=1S/C21H27NO3S2/c1-20(2)9-8-14-12-15(13-16(20)22(14)3)25-19(23)21(24,17-6-4-10-26-17)18-7-5-11-27-18/h4-7,10-11,14-16,24H,8-9,12-13H2,1-3H3/t14-,15-,16-/m1/s1 Key:AMHPTVWBZSYFSS-BZUAXINKSA-N
(verify)

リンク元	「マザチコール」
拡張検索	「mazaticol hydrochloride」