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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/11 10:17:45」(JST)

Mannosidase is an enzyme which hydrolyzes mannose.^[1]

There are two types:

A deficiency is associated with mannosidosis.

References

^ Mannosidases at the US National Library of Medicine Medical Subject Headings (MeSH)

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1. 慢性閉塞性肺疾患（COPD）：危険因子およびリスク低減 chronic obstructive pulmonary disease risk factors and risk reduction
2. ゴーシェ病：治療 gaucher disease treatment

The signaling pathways underlying starvation-induced upregulation of α-mannosidase Ams1 in Saccharomyces cerevisiae.

Umekawa M1, Ujihara M2, Makishima K2, Yamamoto S2, Takematsu H3, Wakayama M2.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Jun;1860(6):1192-201. doi: 10.1016/j.bbagen.2016.02.018. Epub 2016 Mar 4.
BACKGROUND: Cells have evolved the mechanisms to survive nutritional shortages in the environment. In Saccharomyces cerevisiae, α-mannosidase Ams1 is known to play a role in catabolism of N-linked free oligosaccharides in the cytosol. Although, this enzyme is also known to be transported selectivel
PMID 26947009

Aleksanyan H1, Liang J1, Metzenberg S1, Oppenheimer SB2.
Zygote (Cambridge, England).Zygote.2016 May 18:1-8. [Epub ahead of print]
The sea urchin embryo is a United States National Institutes of Health (NIH) designated model system to study mechanisms that may be involved in human health and disease. In order to examine the importance of high-mannose glycans and polysaccharides in gastrulation, Lytechinus pictus embryos were in
PMID 27189235

Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars.

Qian BC1, Kamori A2, Kinami K2, Kato A2, Li YX3, Fleet GW4, Yu CY5.
Organic & biomolecular chemistry.Org Biomol Chem.2016 May 11;14(19):4488-98. doi: 10.1039/c6ob00531d.
Epimerization of C5 of an N-hydroxypyrrolidine ring by regioselective oxidation to a nitrone followed by diastereoselective reduction provides a new approach to the synthesis of swainsonine and related compounds. The only protection in the synthesis of the potent mannosidase inhibitor DIM (1,4-dideo
PMID 27093691

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.

Ninagawa Satoshi,Okada Tetsuya,Sumitomo Yoshiki,Kamiya Yukiko,Kato Koichi,Horimoto Satoshi,Ishikawa Tokiro,Takeda Shunichi,Sakuma Tetsushi,Yamamoto Takashi,Mori Kazutoshi
The Journal of cell biology 206(3), 347-356, 2014-08-04
… We therefore conducted transcription activator-like effector nuclease-mediated gene knockout analysis in human cell line and found that all endogenous EDEMs possess mannosidase activity. …
NAID 120005468381