mannose-binding lectin pathway

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/07 21:12:07」(JST)

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英文文献

  • MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors.
  • Oroszlán G1, Kortvely E2, Szakács D3, Kocsis A1, Dammeier S4, Zeck A5, Ueffing M6, Závodszky P1, Pál G3, Gál P7, Dobó J7.
  • Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Jan 15;196(2):857-65. doi: 10.4049/jimmunol.1501717. Epub 2015 Dec 16.
  • It had been thought that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propeptide is present in blood. The serum of mannose-binding lectin-associated serine protease (MASP)-1/3(-/-) mice contains pro-FD and has markedly reduced alternative pathway activity. It
  • PMID 26673137
  • Mannose-binding lectin polymorphisms and rheumatoid arthritis: A short review and meta-analysis.
  • Epp Boschmann S1, Goeldner I2, Tuon FF3, Schiel W2, Aoyama F2, de Messias-Reason IJ4.
  • Molecular immunology.Mol Immunol.2016 Jan;69:77-85. doi: 10.1016/j.molimm.2015.10.010. Epub 2015 Nov 19.
  • Mannose-binding lectin (MBL) is a pattern recognition receptor of the lectin pathway of complement system. MBL binds to carbohydrates on microorganism's surfaces leading to complement activation, opsonization and phagocytosis. Polymorphisms in the MBL gene (MBL2) are associated with variations on MB
  • PMID 26608926

和文文献

  • C3 Glomerulonephritis Associated with a Missense Mutation in the Factor H Gene
  • Activation of the alternative complement pathway by mannose-binding lectin via a C2-bypass pathway

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★リンクテーブル★
関連記事binding」「pathway」「lectin」「mannose

binding」

  [★]

  • n.
  • adj.
  • 結合性の
affinityassociatebindbondbondingcombineconjoinconjugateconjugationconjunctionconnectconnectionconnectiveconnectivitycoupledockengageengagementjoinligatelinkagesymphysialsymphysicunion

WordNet   license wordnet

「executed with proper legal authority; "a binding contract"」

WordNet   license wordnet

「the protective covering on the front, back, and spine of a book; "the book had a leather binding"」
book binding, cover, back

WordNet   license wordnet

「strip sewn over or along an edge for reinforcement or decoration」

WordNet   license wordnet

「the capacity to attract and hold something」

PrepTutorEJDIC   license prepejdic

「義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料」


pathway」

  [★]

route

WordNet   license wordnet

「a trodden path」
footpath

PrepTutorEJDIC   license prepejdic

「道,小道(path)」


lectin」

  [★] レクチン

WordNet   license wordnet

「any of several plant glycoproteins that act like specific antibodies but are not antibodies in that they are not evoked by an antigenic stimulus」


mannose」

  [★]

マンノース

D-mannose




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