WordNet
- dangerous to health; characterized by progressive and uncontrolled growth (especially of a tumor)
- what an organism looks like as a consequence of the interaction of its genotype and the environment
PrepTutorEJDIC
- 悪意のある,敵意のある / (病気が)悪性の
- 表現型(遺伝子の作用と環境によって表面に出る性質)
UpToDate Contents
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English Journal
- Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?
- Ratajczak MZ1,2, Suszynska M3,4, Kucia M3,4.
- Clinical and translational medicine.Clin Transl Med.2016 Dec;5(1):28. doi: 10.1186/s40169-016-0113-6. Epub 2016 Aug 10.
- The major problem with cancer progression and anti-cancer therapy is the inherent ability of cancer cells to migrate and establish distant metastases. This ability to metastasize correlates with the presence in a growing tumor of cells with a more malignant phenotype, which express certain cancer st
- PMID 27510263
- Cell Polarity Proteins in Breast Cancer Progression.
- Rejon C1, Al-Masri M1, McCaffrey L1.
- Journal of cellular biochemistry.J Cell Biochem.2016 Oct;117(10):2215-23. doi: 10.1002/jcb.25553. Epub 2016 Jun 30.
- Breast cancer, one of the leading causes of cancer related death in women worldwide, is a heterogeneous disease with diverse subtypes that have different properties and prognoses. The developing mammary gland is a highly proliferative and invasive tissue, and some of the developmental programs may b
- PMID 27362918
- Rap2b promotes proliferation, migration, and invasion of lung cancer cells.
- Peng YG1,2, Zhang ZQ2, Chen YB1, Huang JA1.
- Journal of receptor and signal transduction research.J Recept Signal Transduct Res.2016 Oct;36(5):459-64. doi: 10.3109/10799893.2015.1122044. Epub 2015 Dec 16.
- Rap2b, a member of the guanosine triphosphate-binding proteins, is widely up-regulated in many types of tumors. However, the functional role of Rap2b in tumorigenesis of lung cancer remains to be fully elucidated. In this study, we investigated the effect of Rap2b on the lung cancer malignant phenot
- PMID 26671640
Japanese Journal
- Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer
- A novel RET gene mutation in a patient with apparently sporadic pheochromocytoma
- Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome
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- 関
- malignantly、pernicious