major histocompatibility complex molecules

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MHC
MHC

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英文文献

  • Analysis of LC3-Associated Phagocytosis and Antigen Presentation.
  • Ligeon LA1, Romao S1, Münz C2.
  • Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1519:145-168.
  • The noncanonical macroautophagy pathway, LC3-associated phagocytosis (LAP) has recently emerged as an important catabolic process involved during exogenous antigen processing. It has been described that in human macrophages and dendritic cells the direct recruitment of LC3 to the phagosomal membrane
  • PMID 27815878
  • A comparison of cancer stem cell markers and nonclassical major histocompatibility complex antigens in colorectal tumor and noncancerous tissues.
  • Özgül Özdemir RB1, Özdemir AT2, Oltulu F3, Kurt K4, Yiğittürk G3, Kırmaz C5.
  • Annals of diagnostic pathology.Ann Diagn Pathol.2016 Dec;25:60-63. doi: 10.1016/j.anndiagpath.2016.09.012. Epub 2016 Sep 26.
  • Colorectal carcinoma (CRC) is one of the most fatal types of cancer in both women and men, and, unfortunately, patients are often diagnosed at an advanced stage. Cancer stem cells (CSCs) are associated with poor prognosis, metastasis, and recurrence, as well as chemotherapy and radiotherapy resistan
  • PMID 27806848
  • Expression of natural killer cell regulatory microRNA by uveal melanoma cancer stem cells.
  • Joshi P1, Kooshki M2, Aldrich W3, Varghai D1, Zborowski M1, Singh AD4, Triozzi PL5,6.
  • Clinical & experimental metastasis.Clin Exp Metastasis.2016 Dec;33(8):829-838. Epub 2016 Aug 26.
  • Natural killer (NK) cells are implicated in the control of metastasis in uveal melanoma, a process that has been ascribed to its cancer stem cell subpopulation. NK cell activation is regulated by specific microRNA (miR). The NK cell sensitivity and regulatory miR production of uveal melanoma cancer
  • PMID 27565163

和文文献

  • Neuronal major histocompatibility complex class I molecules are implicated in the generation of asymmetries in hippocampal circuitry
  • Kawahara Aiko,Kurauchi Shotaro,Fukata Yuko,Martínez-Hernández José,Yagihashi Terumi,Itadani Yuya,Sho Rui,Kajiyama Taiichi,Shinzato Nao,Narusuye Kenji,Fukata Masaki,Luján Rafael,Shigemoto Ryuichi,Ito Isao,川原 愛子,倉内 翔太郎,深田 優子,八木橋 輝美,板谷 祐也,章 瑠依,梶山 泰一,新里 直,成末 憲治,深田 正紀,重本 隆一,伊藤 功,カワハラ アイコ,クラウチ ショウタロウ,フカタ ユウコ,ヤギハシ テルミ,イタダニ ユウヤ,ショウ ルイ,カジヤマ タイイチ,シンザト ナオ,ナルスエ ケンジ,フカタ マサキ,シゲモト リュウイチ,イトウ イサオ
  • The Journal of Physiology 591(19), 4777-4791, 2013-07-22
  • … To identify key regulators for generating asymmetries, we analysed the hippocampus of β2-microglobulin (β2m)–deficient mice lacking cell surface expression of major histocompatibility complex class I (MHCI). … Our findings provide evidence supporting a critical role of MHCI molecules for generating asymmetries in hippocampal circuitry. …
  • NAID 120005315161
  • Enhanced heterologous protein display on bacterial magnetic particles using a lon protease gene deletion mutant in Magnetospirillum magneticum AMB-1(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
  • Kanetsuki Yuka,Tanaka Tsuyoshi,Matsunaga Tadashi [他],Yoshino Tomoko
  • Journal of bioscience and bioengineering 116(1), 65-70, 2013-07
  • … magneticum AMB-1 cells were transformed using expression plasmids for human proteins, thyroid-stimulating hormone receptor (TSHR) and the class II major histocompatibility complex (MHC II) molecules onto BacMPs. …
  • NAID 110009634747
  • Intratumoral peptide injection enhances tumor cell antigenicity recognized by cytotoxic T lymphocytes: a potential option for improvement in antigen-specific cancer immunotherapy
  • Nobuoka Daisuke,Yoshikawa Toshiaki,Takahashi Mari,Iwama Tatsuaki,Horie Kazutaka,Shimomura Manami,Suzuki Shiro,Sakemura Noriko,Nakatsugawa Munehide,Sadamori Hiroshi,Yagi Takahito,Fujiwara Toshiyoshi,Nakatsura Tetsuya
  • Cancer Immunology, Immunotherapy 62(4), 639-652, 2013-04
  • … Here, we demonstrated that intratumoral peptide injection leads to additional peptide loading onto major histocompatibility complex class I molecules of tumor cells, enhancing tumor cell recognition by antigen-specific CTLs. … In in vivo studies using immunodeficient mice, glypican-3(144-152) and cytomegalovirus(495-503) peptides injected into a solid mass were loaded onto HLA class I molecules of tumor cells. …
  • NAID 120005315577

関連リンク

major histocompatibility complex (MHC), major histocompatibility complex David S. Goodsell/Protein Data Bank/Research Collaboratory for Structural Bioinformatics (RCSB) group of genes that code for proteins found on the surfaces ...
The most rapid and severe rejection of foreign tissue occurs when there is a failure to properly match the donor and recipient for the major histocompatibility molecules. There are two categories: class I and class II. Class I ...

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Major Histocompatibility Complex Mhc Class fig003smc.gif (10513 bytes)Wikipedia Youtube News Books Twitter of « Major histocompatibility complexMajor Histocompatibility Complex Mhc Class Role of MHC molecules.


★リンクテーブル★
先読みMHC
関連記事major」「complex」「molecule」「histocompatibility」「Major

MHC」

  [★] 主要組織適合複合体 major histocompatibility complex


major」

  [★]

  • adj.
  • 主要な、主な、専攻する、メジャーな
cardinalchiefchieflyforemostmainmainlymastermostlypredominantpredominantlyprimarilyprimaryprincipalprincipally

WordNet   license wordnet

「of the field of academic study in which one concentrates or specializes; "his major field was mathematics"」

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「a commissioned military officer in the United States Army or Air Force or Marines; below lieutenant colonel and above captain」

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「a university student who is studying a particular field as the principal subject; "she is a linguistics major"」

WordNet   license wordnet

「the principal field of study of a student at a university; "her major is linguistics"」

PrepTutorEJDIC   license prepejdic

「『大きい』(『多い』)『ほうの』,いっそう重要な / (音階が)長調の,長音階の / 《英》《昔の学校で同姓または兄弟生徒を区別するために姓の後につけて》年長の,兄の / 《しばしばM-》陸軍(空軍)少佐 / 《米》専攻科目;専攻学生 / 《the majors》《米》=major leagues / (科目を)専攻する《+『in』+『名』》」

WordNet   license wordnet

「greater in number or size or amount; "a major portion (a majority) of the population"; "Ursa Major"; "a major portion of the winnings"」

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「greater in scope or effect; "a major contribution"; "a major improvement"; "a major break with tradition"; "a major misunderstanding"」

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「have as one''s principal field of study; "She is majoring in linguistics"」

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「of a scale or mode; "major scales"; "the key of D major"」

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「of full legal age」

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「of greater importance or stature or rank; "a major artist"; "a major role"; "major highways"」

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「of greater seriousness or danger; "a major earthquake"; "a major hurricane"; "a major illness"」

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「of the elder of two boys with the same family name; "Jones major"」


complex」

  [★]

  • n.
  • adj.
  • 複雑な、複合の
complexescomplicatedcompositeconjugateintricate

WordNet   license wordnet

「complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"」

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「a compound described in terms of the central atom to which other atoms are bound or coordinated」
coordination compound

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「a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town"」
composite

WordNet   license wordnet

「(psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a person''s behavior」

PrepTutorEJDIC   license prepejdic

「『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)」


molecule」

  [★]

molmolecularnumerator

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「(physics and chemistry) the simplest structural unit of an element or compound」

PrepTutorEJDIC   license prepejdic

「分子《略》『mol』) / (一般に)(…の)微量《+『of』+『名』》」


histocompatibility」

  [★]

histocompatabilityhistocompatible

WordNet   license wordnet

「condition in which the cells of one tissue can survive in the presence of cells of another tissue; "a successful graft or transplant requires a high degree of histocompatibility"」


Major」

  [★]

WordNet   license wordnet

「British statesman who was prime minister from 1990 until 1997 (born in 1943)」
John Major, John R. Major, John Roy Major



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