magnesium sulfate

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硫酸マグネシウム

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/03 17:47:16」(JST)

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英文文献

  • Influence of sulphate on the composition and antibacterial and antiviral properties of the exopolysaccharide from Porphyridium cruentum.
  • Raposo MF1, de Morais AM1, de Morais RM2.Author information 1CBQF - Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal.2CBQF - Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal. Electronic address: rcmorais@porto.ucp.pt.AbstractAIMS: The influence of two culture media and three different concentrations of sulphate in the medium on the growth of two strains of Porphyridium cruentum and on the production, composition and viscoelastic characteristics, and antimicrobial properties of the sulphated exopolysaccharide (EPS) were studied.
  • Life sciences.Life Sci.2014 Apr 17;101(1-2):56-63. doi: 10.1016/j.lfs.2014.02.013. Epub 2014 Feb 25.
  • AIMS: The influence of two culture media and three different concentrations of sulphate in the medium on the growth of two strains of Porphyridium cruentum and on the production, composition and viscoelastic characteristics, and antimicrobial properties of the sulphated exopolysaccharide (EPS) were
  • PMID 24582595
  • The efficacy of nebulized salbutamol, magnesium sulfate, and salbutamol/magnesium sulfate combination in moderate bronchiolitis.
  • Kose M1, Ozturk MA, Poyrazoğlu H, Elmas T, Ekinci D, Tubas F, Kurt T, Goktas MA.Author information 1Department of Pediatric Pulmonology, Erciyes University Faculty of Medicine, Pediatric Pulmonology Unit, Kayseri, 38000, Turkey, mhmtkose@yahoo.com.AbstractThe aim of this paper is to compare the effect of nebulized magnesium sulfate to nebulized salbutamol and salbutamol/magnesium sulfate on successful discharge from the emergency department. A total of 56 infants were included in this double-blinded, prospective study. Infants were grouped according to the nebulized treatment they received: group 1-salbutamol/normal saline, group 2-magnesium sulfate and normal saline, and group 3-salbutamol plus magnesium sulfate. Heart beat, bronchiolitis, clinical severity scores (CSS), and oxygen saturation of the patients were determined before and after nebulization (0, 1, 4 h). The patients were monitored for adverse reactions. Post-treatment mean CSS results were significantly lower than pre-treatment scores in all groups at 4 h with no significant difference within groups. CSS scores were lower in the salbutamol/magnesium sulfate group when compared with the magnesium sulfate and salbutamol groups (3.4 (2.4-4.3), 4.7 (3.8-5.7), 4.0 (3.2-4.3)). CSS were significantly lower than those from the magnesium sulfate group. Conclusion: Nebulized magnesium sulfate plus salbutamol may have additive effects for improving the short-term CSS.
  • European journal of pediatrics.Eur J Pediatr.2014 Apr 2. [Epub ahead of print]
  • The aim of this paper is to compare the effect of nebulized magnesium sulfate to nebulized salbutamol and salbutamol/magnesium sulfate on successful discharge from the emergency department. A total of 56 infants were included in this double-blinded, prospective study. Infants were grouped according
  • PMID 24687251
  • Treatment of hypomagnesemia.
  • Ayuk J1, Gittoes NJ2.Author information 1Department of Endocrinology, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.2Department of Endocrinology, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom. Electronic address: neil.gittoes@uhb.nhs.uk.AbstractSerum magnesium concentration is determined by the interplay of intestinal absorption and renal excretion. Hypomagnesemia can occur as a result of insufficient magnesium intake, increased gastrointestinal or renal loss, or redistribution from extracellular to intracellular compartments. A number of drugs are known to cause hypomagnesemia, including proton pump inhibitors (PPIs). We report the case of a patient with symptomatic hypomagnesemia due to short bowel syndrome and PPI therapy. Investigations revealed low 24-hour urinary magnesium excretion and secondary hypocalcemia. PPI treatment was withdrawn and the patient was managed with intravenous and oral magnesium and calcium replacement. This teaching case provides an evidence-based discussion of the treatment of hypomagnesemia.
  • American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2014 Apr;63(4):691-5. doi: 10.1053/j.ajkd.2013.07.025. Epub 2013 Oct 4.
  • Serum magnesium concentration is determined by the interplay of intestinal absorption and renal excretion. Hypomagnesemia can occur as a result of insufficient magnesium intake, increased gastrointestinal or renal loss, or redistribution from extracellular to intracellular compartments. A number of
  • PMID 24100128

和文文献

  • Preparation of monodisperse aqueous microspheres containing high concentration of l-ascorbic acid by microchannel emulsification
  • ISP-14-2 Magnesium sulfate enables fetal intrapartum surveillance by suppressing fetal supraventricular extrasystole : Two case reports(Group 14 Perinatology 4,IS Poster,International Session)
  • Hydrochemical characteristics and sources of brines in the Gasikule salt lake, Northwest Qaidam Basin, China

関連リンク

Magnesium Sulfate official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... The potential incompatibility will often be influenced by the changes in the ...
Easy to read patient leaflet for magnesium sulfate. Includes indications, proper use, special instructions, precautions, and possible side effects. ... If OVERDOSE is suspected: Contact 1-800-222-1222 (the American Association of ...

関連画像

Magnesium Sulfate : United Nuclear de magnesium le sulfate de magnesium Magnesium sulfate (anhydrous); Magnesium Magnesium Sulfate InjectionDescription Magnesium Sulfate (1).JPGMagnesium Sulfate - Home


★リンクテーブル★
リンク元硫酸マグネシウム」「マグネシウム
拡張検索magnesium sulfate hydrate
関連記事sulfate」「magnesium」「sulfated」「sulfa

硫酸マグネシウム」

  [★]

magnesium sulfate
MgSO4
マグネゾール硫酸マグネシウム水和物、(子宮収縮抑制剤)マグセント
アミグランドアミノトリパ1号アミノフリードアミノレバンEN配合エルネオパ1号エレンタールP乳幼児用配合オペガードコントミンサイリジンツインパルツインラインNF配合ツインライン配合トリパレン1号ネオパレン1号ハイカリック液-1号パレセーフピーエヌツイン-1号ビーフリードピシバニールフェニルアラニン除去ミルク配合プロモーションヘパンED配合マグセントマグネゾールミキシッドLユニカリックLロイシン・イソロイシン・バリン除去ミルク配合硫酸Mg硫酸マグネシウム水和物
マグネシウム

作用機序

瀉下薬として

  • イオンの吸収は、PO43-<SO42-<NO3-<Br-<Cl-、Mg2+<Ca2+<Na+<K+の順に吸収されにくいので、MgSO4は腸管で吸収されにくい。難吸収性の塩類は腸管内水分および分泌液の吸収を阻止し、また塩濃度が高い場合等張となるまで水分を腸管に引き込む。この結果、腸管内容量が増し、反射的に蠕動が亢進し水様便が排泄される。(SPC.309)

子宮収縮の抑制薬として

  • カルシウムと拮抗して平滑筋を弛緩させる
  • 硫酸マグネシウムの投与により、急速に血中濃度を治療域まで上昇させ、その後1-2g/hrぐらいで維持する。血中Mg濃度を測定し、子宮収縮や副作用を見ながら増減する。
  • 腎臓から排泄されるため、腎機能低下や尿量減少により副作用が出やすくなる。

参考1

  • 詳細な機序は不明。細胞膜の電位依存性チャネルでCa2+と競合すると考えられている。細胞膜を過分極させ、そしてこの場所で(細胞膜のレベルで?)細胞内のカルシウムと競合してミオシン軽鎖キナーゼ活性を抑制する。

副作用

子宮収縮の抑制薬として

  • 母体:顔面紅潮、嘔気、嘔吐、頭痛、筋力低下、深部反射の消失、呼吸抑制
  • 胎児:胎児心拍数の基線細変動の現象、胎児呼吸様運動の抑制
  • 新生児:新生児の高マグネシウム血症、呼吸障害、筋緊張低下、消化管の運動障害、低カルシウム血症

参考

  • 1. Inhibition of acute preterm labor - uptodate [1]




マグネシウム」

  [★]

magnesium Mg
硫酸マグネシウム magnesium sulfate電解質異常
クエン酸マグネシウム 緩下剤

基準値

  • 血漿/血清:1.5-2mEq/L 1.8-2.4mg/dl, 1.5-2.0mEq/L 1.7-2.4mg/dl(HIM.2372)

臨床関連

参考

  • 1. [charged] Regulation of magnesium balance - uptodate [2]
腎臓におけるマグネシウムの再吸収メカニズムがよく分かる





magnesium sulfate hydrate」

  [★]

magnesium sulfateMgSO4


sulfate」

  [★]

  • n.
H2SO4inorganic sulfatesulfate estersulfatedsulfationsulfuric acidsulfuric acid estersulphatesulphuric acid


WordNet   license wordnet

「convert into a sulfate」

WordNet   license wordnet

「a salt or ester of sulphuric acid」
sulphate


magnesium」

  [★] マグネシウムMg+

WordNet   license wordnet

「a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine)」
Mg, atomic number 12

PrepTutorEJDIC   license prepejdic

「マグネシウム(金属元素;化学記号は『Mg』)」


sulfated」

  [★]

  • adj.
  • 硫酸化の
sulfatesulfationsulphate


sulfa」

  [★]

スルファサルファ




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